List of works - Aiwu Zhou

14-3-3τ promotes surface expression of Cav2.2 (α1B) Ca2+ channels

scientific article

A novel "mosaic-type" nanoparticle for selective drug release targeting hypoxic cancer cells

scientific article published on 01 January 2019

A redox mechanism underlying nucleolar stress sensing by nucleophosmin

scientific article

A redox switch in angiotensinogen modulates angiotensin release

scientific article

Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid-binding Globulins

scientific article

Antithrombin 'DREUX' (Lys 114Glu): a variant with complete loss of heparin affinity.

scientific article published in September 2002

Characterization of PPIB interaction in the P3H1 ternary complex and implications for its pathological mutations

scientific article published on 16 April 2019

Crystal Structures of PI3Kα Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design

scientific article

Crystal structure of protein Z-dependent inhibitor complex shows how protein Z functions as a cofactor in the membrane inhibition of factor X

scientific article

Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes

scientific article

Crystallization and crystallographic studies of kallistatin

scientific article published on 25 August 2015

DUSP6 SUMOylation protects cells from oxidative damage via direct regulation of Drp1 dephosphorylation

scientific article published on 25 March 2020

Dimers initiate and propagate serine protease inhibitor polymerisation.

scientific article published on 25 October 2007

Formation of the antithrombin heterodimer in vivo and the onset of thrombosis.

scientific article

Functional structure of the somatomedin B domain of vitronectin

scientific article

Glyceraldehyde 3-phosphate dehydrogenase is required for band 3 (anion exchanger 1) membrane residency in the mammalian kidney

scientific journal article

Helix D elongation and allosteric activation of antithrombin.

scientific article published on 10 December 2001

Heparin Blocks the Inhibition of Tissue Kallikrein 1 by Kallistatin through Electrostatic Repulsion

scientific article published on 28 May 2020

Heparin binds lamprey angiotensinogen and promotes thrombin inhibition through a template mechanism

scientific article

How changes in affinity of corticosteroid-binding globulin modulate free cortisol concentration

scientific article

How small peptides block and reverse serpin polymerisation.

scientific article published in September 2004

How vitronectin binds PAI-1 to modulate fibrinolysis and cell migration

scientific article

Human H+ATPase a4 subunit mutations causing renal tubular acidosis reveal a role for interaction with phosphofructokinase-1 ⬇️

scientific article

Insights into Hunter syndrome from the structure of iduronate-2-sulfatase

scientific article

Modulation of serpin reaction through stabilization of transient intermediate by ligands bound to alpha-helix F.

scientific article published on 5 July 2007

Molecular Mechanism of Z α1-Antitrypsin Deficiency

scientific article published on 31 May 2016

Physical and functional links between anion exchanger-1 and sodium pump

scientific article

Plasminogen activator inhibitor-1 fused with erythropoietin (EPO) mimetic peptide (EMP) enhances the EPO activity of EMP

scientific article published on 01 August 2000

Polymerization of plasminogen activator inhibitor-1.

scientific article

Probing nanosecond motions of plasminogen activator inhibitor-1 by time-resolved fluorescence anisotropy

scientific article published on 07 May 2009

Serpin polymerization is prevented by a hydrogen bond network that is centered on his-334 and stabilized by glycerol

scientific article (publication date: 25 April 2003)

Serpins as hormone carriers: modulation of release

scientific article published on 01 January 2011

Serpins show structural basis for oligomer toxicity and amyloid ubiquity.

scientific article published on 23 June 2008

Snail recruits Ring1B to mediate transcriptional repression and cell migration in pancreatic cancer cells

scientific article

Solving serpin crystal structures

scientific article published in January 2011

Structural basis for catalytic activation of protein Z-dependent protease inhibitor (ZPI) by protein Z

scientific article

Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis

scientific article published on 23 October 2019

Structural basis for the specificity of renin-mediated angiotensinogen cleavage.

scientific article

Structural basis of a novel PD-L1 nanobody for immune checkpoint blockade

scientific article published on 07 March 2017

Structural mechanism for the carriage and release of thyroxine in the blood

scientific article

Structure of the cytochrome aa 3 -600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site

scientific article published on 30 December 2019

Temperature-responsive release of cortisol from its binding globulin: a protein thermocouple.

scientific article published on 14 July 2010

Temperature-responsive release of thyroxine and its environmental adaptation in Australians

article

The S-to-R transition of corticosteroid-binding globulin and the mechanism of hormone release

scientific article

The a-subunit of the V-type H+-ATPase interacts with phosphofructokinase-1 in humans

scientific article

Thermodynamic and kinetic characterization of the protein Z-dependent protease inhibitor (ZPI)-protein Z interaction reveals an unexpected role for ZPI Lys-239.

scientific article

Towards engineering hormone-binding globulins as drug delivery agents

scientific article

List of works by Aiwu Zhou

14-3-3τ promotes surface expression of Cav2.2 (α1B) Ca2+ channels

A novel "mosaic-type" nanoparticle for selective drug release targeting hypoxic cancer cells

A redox mechanism underlying nucleolar stress sensing by nucleophosmin

A redox switch in angiotensinogen modulates angiotensin release

Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid-binding Globulins

Antithrombin 'DREUX' (Lys 114Glu): a variant with complete loss of heparin affinity.

Characterization of PPIB interaction in the P3H1 ternary complex and implications for its pathological mutations

Crystal Structures of PI3Kα Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design

Crystal structure of protein Z-dependent inhibitor complex shows how protein Z functions as a cofactor in the membrane inhibition of factor X

Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes

Crystallization and crystallographic studies of kallistatin

DUSP6 SUMOylation protects cells from oxidative damage via direct regulation of Drp1 dephosphorylation

Dimers initiate and propagate serine protease inhibitor polymerisation.

Formation of the antithrombin heterodimer in vivo and the onset of thrombosis.

Functional structure of the somatomedin B domain of vitronectin

Glyceraldehyde 3-phosphate dehydrogenase is required for band 3 (anion exchanger 1) membrane residency in the mammalian kidney

Helix D elongation and allosteric activation of antithrombin.

Heparin Blocks the Inhibition of Tissue Kallikrein 1 by Kallistatin through Electrostatic Repulsion

Heparin binds lamprey angiotensinogen and promotes thrombin inhibition through a template mechanism

How changes in affinity of corticosteroid-binding globulin modulate free cortisol concentration

How small peptides block and reverse serpin polymerisation.

How vitronectin binds PAI-1 to modulate fibrinolysis and cell migration

Human H+ATPase a4 subunit mutations causing renal tubular acidosis reveal a role for interaction with phosphofructokinase-1 ⬇️

Insights into Hunter syndrome from the structure of iduronate-2-sulfatase

Modulation of serpin reaction through stabilization of transient intermediate by ligands bound to alpha-helix F.

Molecular Mechanism of Z α1-Antitrypsin Deficiency

Physical and functional links between anion exchanger-1 and sodium pump

Plasminogen activator inhibitor-1 fused with erythropoietin (EPO) mimetic peptide (EMP) enhances the EPO activity of EMP

Polymerization of plasminogen activator inhibitor-1.

Probing nanosecond motions of plasminogen activator inhibitor-1 by time-resolved fluorescence anisotropy

Serpin polymerization is prevented by a hydrogen bond network that is centered on his-334 and stabilized by glycerol

Serpins as hormone carriers: modulation of release

Serpins show structural basis for oligomer toxicity and amyloid ubiquity.

Snail recruits Ring1B to mediate transcriptional repression and cell migration in pancreatic cancer cells

Solving serpin crystal structures

Structural basis for catalytic activation of protein Z-dependent protease inhibitor (ZPI) by protein Z

Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis

Structural basis for the specificity of renin-mediated angiotensinogen cleavage.

Structural basis of a novel PD-L1 nanobody for immune checkpoint blockade

Structural mechanism for the carriage and release of thyroxine in the blood

Structure of the cytochrome aa 3 -600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site

Temperature-responsive release of cortisol from its binding globulin: a protein thermocouple.

Temperature-responsive release of thyroxine and its environmental adaptation in Australians

The S-to-R transition of corticosteroid-binding globulin and the mechanism of hormone release

The a-subunit of the V-type H+-ATPase interacts with phosphofructokinase-1 in humans

Thermodynamic and kinetic characterization of the protein Z-dependent protease inhibitor (ZPI)-protein Z interaction reveals an unexpected role for ZPI Lys-239.

Towards engineering hormone-binding globulins as drug delivery agents