Search filters

List of works by Stefano Santaguida

A general framework for inhibitor resistance in protein kinases.

scientific article

A high throughput, whole cell screen for small molecule inhibitors of the mitotic spindle checkpoint identifies OM137, a novel Aurora kinase inhibitor

scientific article

A monoclonal antibody specific for prophase phosphorylation of histone deacetylase 1: a readout for early mitotic cells.

scientific article published on 14 October 2015

A screen for kinetochore-microtubule interaction inhibitors identifies novel antitubulin compounds

scientific article

A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B

scientific article

Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis.

scientific article published on 3 August 2017

Aneuploid senescent cells activate NF-κB to promote their immune clearance by NK cells

scientific article published on 08 June 2021

Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition

scientific article published on 27 January 2021

Aneuploidy triggers a TFEB-mediated lysosomal stress response

scientific article published on 16 November 2015

Aneuploidy-induced cellular stresses limit autophagic degradation

scientific article

Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System

scientific article published in June 2017

Crystal Structure of Human Aurora B in Complex with INCENP and VX-680

scientific article

Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine

scientific article

Dynamic phosphorylation of Histone Deacetylase 1 by Aurora kinases during mitosis regulates zebrafish embryos development.

scientific article published on 26 July 2016

Early cerebrovascular and parenchymal events following prenatal exposure to the putative neurotoxin methylazoxymethanol

scientific article

Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction ⬇️

scientific article

Generation and Isolation of Cell Cycle-arrested Cells with Complex Karyotypes

scientific article published on 13 April 2018

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Homeostatic Control of Mitotic Arrest

scientific article published on 01 December 2011

Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex

scientific article

Norepinephrine-mediated regulation of 5HT1 receptor functioning in human platelets.

scientific article

Protein aggregation mediates stoichiometry of protein complexes in aneuploid cells

scientific article published on 13 June 2019

Selective Aurora Kinase Inhibitors Identified Using a Taxol-Induced Checkpoint Sensitivity Screen

scientific article

Short- and long-term effects of chromosome mis-segregation and aneuploidy

scientific article

Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery

scientific article

Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction

scientific article

Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex

scientific article

The Aurora B kinase activity is required for the maintenance of the differentiated state of murine myoblasts.

scientific article

The MIS12 complex is a protein interaction hub for outer kinetochore assembly

scientific article

The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint

scientific article

The life and miracles of kinetochores

scientific article

The pleiotropic deubiquitinase Ubp3 confers aneuploidy tolerance

scientific article

Paulina is supported by:

About Paulina

Help