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List of works by Yoshinori Fukui

A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress

scientific article

A functional genomics predictive network model identifies regulators of inflammatory bowel disease

scientific article published on 11 September 2017

ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation.

scientific article

Ablation of the microglial protein DOCK2 reduces amyloid burden in a mouse model of Alzheimer's disease.

scientific article published on 11 January 2013

Addendum: defective Dock2 expression in a subset of ASC-deficient mouse lines.

scientific article published on July 2012

Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse

scientific article

Antigen Availability and DOCK2-Driven Motility Govern CD4+ T Cell Interactions with Dendritic Cells In Vivo.

scientific article published on 12 June 2017

Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion

scientific article

Blockade of inflammatory responses by a small-molecule inhibitor of the Rac activator DOCK2.

scientific article

CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway

scientific article

Cholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye

scientific article published on 31 July 2018

Comprehensive analysis of lymph node stroma-expressed Ig superfamily members reveals redundant and nonredundant roles for ICAM-1, ICAM-2, and VCAM-1 in lymphocyte homing

scientific article

Correction: Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse.

scientific article published on 14 March 2017

Corrigendum to "Thymic epithelial cell-specific deletion of Jmjd6 reduces aire protein expression and exacerbates disease development in a mouse model of autoimmune diabetes" [Biochemical and Biophysical Research Communications 489/1 (2017) 8-13].

scientific article published on 7 August 2017

DOCK family proteins: key players in immune surveillance mechanisms

scientific article published on 01 January 2020

DOCK1 inhibition suppresses cancer cell invasion and macropinocytosis induced by self-activating Rac1P29S mutation

scientific article published on 9 February 2018

DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4.

scientific article published on 9 September 2010

DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formation

scientific article

DOCK2 confers immunity and intestinal colonization resistance to Citrobacter rodentium infection

scientific article published on 13 June 2016

DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis

scientific article

DOCK2 is a microglial specific regulator of central nervous system innate immunity found in normal and Alzheimer's disease brain.

scientific article published on 03 September 2009

DOCK2 is critical for CD8(+) TCR(-) graft facilitating cells to enhance engraftment of hematopoietic stem and progenitor cells.

scientific article published in October 2014

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

scientific journal article

DOCK2 regulates Rac activation and cytoskeletal reorganization through interaction with ELMO1

scientific article (publication date: 15 October 2003)

DOCK2 regulates chemokine-triggered lateral lymphocyte motility but not transendothelial migration

scientific article

DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation

scientific article

DOCK8 Protein Regulates Macrophage Migration through Cdc42 Protein Activation and LRAP35a Protein Interaction

scientific article published on 27 December 2016

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

scientific article

Dedicator of cytokinesis 2, a novel regulator for smooth muscle phenotypic modulation and vascular remodeling.

scientific article published on 18 March 2015

Defective fetal liver erythropoiesis and T lymphopoiesis in mice lacking the phosphatidylserine receptor

scientific journal article

Deletion of DOCK2, a regulator of the actin cytoskeleton in lymphocytes, suppresses cardiac allograft rejection

scientific article published on October 2005

Development of peptide vaccines inducing production of neutralizing antibodies against HIV-1 viruses in HLA-DQ6 mice ⬇️

scientific article published on October 1, 1998

Differential requirement for DOCK2 in migration of plasmacytoid dendritic cells versus myeloid dendritic cells

scientific article

Differential requirement of MHC class II molecules expressed on hematopoietic cells for positive selection of CD4+ thymocytes in TCR alpha beta and TCR beta transgenic mice.

scientific article published in September 1997

Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing

scientific article published in September 2004

Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration.

scientific article

Diversity of T cell repertoire shaped by a single peptide ligand is critically affected by its amino acid residue at a T cell receptor contact.

scientific article published on December 2000

Dock2 participates in bone marrow lympho-hematopoiesis

scientific article published on 26 December 2007

Emerging role of interleukin-31 and interleukin-31 receptor in pruritus in atopic dermatitis

scientific article published on 3 July 2017

Functional interaction between human histocompatibility leukocyte antigen (HLA) class II and mouse CD4 molecule in antigen recognition by T cells in HLA-DR and DQ transgenic mice.

scientific article published on July 1994

GLYCOSURIA AND INSULITIS IN NOD MICE EXPRESSING THE HLA-DQw6 MOLECULE

scientific article published on 01 December 1989

Global lymphoid tissue remodeling during a viral infection is orchestrated by a B cell-lymphotoxin-dependent pathway

scientific article published on 25 February 2010

Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

scientific journal article

Highly Restricted T Cell Repertoire Shaped by a Single Major Histocompatibility Complex–Peptide Ligand in the Presence of a Single Rearranged T Cell Receptor β Chain ⬇️

scientific article published on September 7, 1998

Hla-DR2-restricted responses to proteolipid protein 95-116 peptide cause autoimmune encephalitis in transgenic mice

scientific article published on April 2000

Id2-, RORgammat-, and LTbetaR-independent initiation of lymphoid organogenesis in ocular immunity

scientific article published on 12 October 2009

Immune regulatory functions of DOCK family proteins in health and disease

scientific article published on 02 August 2013

Involvement of the lysophosphatidic acid-generating enzyme autotaxin in lymphocyte-endothelial cell interactions

scientific article published on 25 September 2008

Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6)

scientific article published on 9 January 2013

Methylprednisolone injection via the portal vein suppresses inflammation in acute liver failure induced in rats by lipopolysaccharide and d-galactosamine

scientific article published on 26 September 2007

Mitochondrial p32/C1qbp Is a Critical Regulator of Dendritic Cell Metabolism and Maturation

scientific article published on 01 November 2018

Neutrophils scan for activated platelets to initiate inflammation.

scientific article published on 4 December 2014

Next-generation sequencing coupled with a cell-free display technology for high-throughput production of reliable interactome data

scientific article

Organ-specific autoimmunity in mice whose T cell repertoire is shaped by a single antigenic peptide

scientific article

P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils.

scientific article published on 21 March 2014

Parallel Regulation of von Hippel-Lindau Disease by pVHL-Mediated Degradation of B-Myb and Hypoxia-Inducible Factor α.

scientific article published on 18 April 2016

Phosphatidic acid-dependent recruitment and function of the Rac activator DOCK1 during dorsal ruffle formation

scientific article published on 29 January 2013

Positive and Negative CD4+ Thymocyte Selection by a Single MHC Class II/Peptide Ligand Affected by Its Expression Level in the Thymus

scientific article published on 01 April 1997

Prevention of infection of influenza virus in DQ6 mice, a human model, by a peptide vaccine prepared according to the cassette theory.

scientific article published in March 1999

Quantitative Analysis of the T Cell Repertoire Selected by a Single Peptide–Major Histocompatibility Complex ⬇️

scientific article published on June 1, 1998

Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis

scientific article published on 16 April 2013

Restricted expression of transgenic HLA-DRA gene in thymic epithelial cells and its role in acquisition of T cell tolerance to self-superantigens and processed DRα-derived peptide

article

Role of DOCK2 and DOCK180 in fetal thymus colonization

scientific article published on 01 October 2009

Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation.

scientific article

Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis.

scientific article

Shigella IpgB1 promotes bacterial entry through the ELMO-Dock180 machinery.

scientific article published on 17 December 2006

Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms

scientific article

T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-alpha subunit controlled by the Rac activator Dock2.

scientific article published on 2 September 2007

T-cell repertoire in a strain of transgenic C57BL/6 mice with the HLA-DRA gene on the X-chromosome

article

Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1.

scientific article

The A3 allele of the HLA-DQA1 locus is associated with susceptibility to type 1 diabetes in Japanese

scientific article

The AP-1 transcription factor JunB is required for Th17 cell differentiation

scientific article published on 12 December 2017

The Rac Activator DOCK2 Mediates Plasma Cell Differentiation and IgG Antibody Production.

scientific article published on 16 February 2018

The Rac activator DOCK2 regulates natural killer cell-mediated cytotoxicity in mice through the lytic synapse formation

scientific article

The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo

scientific article

The cell polarity protein mInsc regulates neutrophil chemotaxis via a noncanonical G protein signaling pathway

scientific article published on 25 July 2013

The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization

scientific journal article

The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction

scientific article

Thromboxane A2 acts as tonic immunoregulator by preferential disruption of low-avidity CD4+ T cell-dendritic cell interactions

scientific article

Thymic epithelial cell-specific deletion of Jmjd6 reduces Aire protein expression and exacerbates disease development in a mouse model of autoimmune diabetes.

scientific article published on 22 May 2017

Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2.

scientific article

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