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List of works by Niels Behrendt

A 55,000-60,000 Mr receptor protein for urokinase-type plasminogen activator. Identification in human tumor cell lines and partial purification

scientific article published on 01 February 1988

A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor

scientific article

A monoclonal antibody interferes with TIMP-2 binding and incapacitates the MMP-2-activating function of multifunctional, pro-tumorigenic MMP-14/MT1-MMP.

scientific article published on 02 December 2013

A novel polymorphism of human complement component C3 detected by means of a monoclonal antibody

scientific article published on 01 January 1986

A novel, specific pro-urokinase complex on monocyte-like cells, detected by transglutaminase-catalyzed cross-linking

scientific article

A urokinase receptor-associated protein with specific collagen binding properties

scientific article

Advances in targeted delivery of small interfering RNA using simple bioconjugates

scientific article published on 26 March 2014

Antibody-mediated Targeting of the Urokinase-type Plasminogen Activator Proteolytic Function Neutralizes Fibrinolysisin Vivo

scientific article published on 17 September 2008

Binding of the urokinase-type plasminogen activator to its cell surface receptor is inhibited by low doses of suramin.

scientific article published in March 1993

Cell-surface acceleration of urokinase-catalyzed receptor cleavage

scientific article published on 01 January 1997

Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol ⬇️

scientific article published on January 25, 1991

Complementary roles of intracellular and pericellular collagen degradation pathways in vivo.

scientific article

Complex determinants in specific members of the mannose receptor family govern collagen endocytosis

scientific article published on 05 February 2014

Conformational regulation of urokinase receptor function: impact of receptor occupancy and epitope-mapped monoclonal antibodies on lamellipodia induction.

scientific article

Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding

scientific article

Defective TAFI activation in hemophilia A mice is a major contributor to joint bleeding

scientific article published on 19 July 2018

Different mechanisms are involved in the antibody mediated inhibition of ligand binding to the urokinase receptor: a study based on biosensor technology

scientific article published on 01 January 1999

Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasis

scientific article

Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells

scientific article

Domain interplay in the urokinase receptor. Requirement for the third domain in high affinity ligand binding and demonstration of ligand contact sites in distinct receptor domains.

scientific article published on September 1996

ELISA for complexes between urokinase-type plasminogen activator and its receptor in lung cancer tissue extracts

scientific article published on 01 July 1997

Effect of purified, soluble urokinase receptor on the plasminogen-prourokinase activation system

scientific article published on 01 September 1996

Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis

scientific article published on 17 February 2012

Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation.

scientific article

Ficolin-1-PTX3 complex formation promotes clearance of altered self-cells and modulates IL-8 production

scientific article published in July 2013

Human complement component C3: characterization of active C3 S and C3 F, the two common genetic variants

Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins

scientific article published on 26 October 2018

Increased Expression of the Collagen Internalization Receptor uPARAP/Endo180 in the Stroma of Head and Neck Cancer

scientific article published on 22 December 2006

Inhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo ⬇️

scientific article published on June 28, 2012

Localization and functional significance of a polymorphic determinant in the third component of human complement.

scientific article published in October 1987

M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway

scientific article

MT1-MMP and type II collagen specify skeletal stem cells and their bone and cartilage progeny.

scientific article

Matrix metalloproteinase 2 and membrane type 1 matrix metalloproteinase co-regulate axonal outgrowth of mouse retinal ganglion cells.

scientific article published on 27 March 2014

New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment.

scientific article published on 17 July 2012

Phagocytosis of Collagen Fibrils by Fibroblasts In Vivo Is Independent of the uPARAP/Endo180 Receptor.

scientific article published on 6 December 2016

Plasminogen activation and cancer

scientific article published on 01 April 2005

Plasminogen activation by receptor-bound urokinase. A kinetic study with both cell-associated and isolated receptor ⬇️

scientific article published on July 5, 1991

Plasminogen-independent initiation of the pro-urokinase activation cascade in vivo. Activation of pro-urokinase by glandular kallikrein (mGK-6) in plasminogen-deficient mice

scientific article published on 01 January 2000

Quantitation of the receptor for urokinase plasminogen activator by enzyme-linked immunosorbent assay

scientific article published on 01 January 1994

Reply to comment on 'Effect of purified, soluble urokinase receptor on the plasminogen-prourokinase activation system' (A. A-R. Higazi)

scientific article published on 01 February 1997

TAFI deficiency causes maladaptive vascular remodeling after hemophilic joint bleeding

scientific article published on 03 October 2019

Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180

Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis

scientific article published on 14 February 2013

The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers.

scientific article

The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review)

scientific article (publication date: October 2015)

The collagen receptor uPARAP/Endo180.

scientific article published on January 2009

The intact urokinase receptor is required for efficient vitronectin binding: receptor cleavage prevents ligand interaction

scientific article published on 01 December 1997

The ligand-binding domain of the cell surface receptor for urokinase-type plasminogen activator ⬇️

scientific article published on April 25, 1991

The non-phagocytic route of collagen uptake: a distinct degradation pathway

scientific article

The pro-urokinase plasminogen-activation system in the presence of serpin-type inhibitors and the urokinase receptor: rescue of activity through reciprocal pro-enzyme activation.

scientific article published in April 2003

The urokinase receptor (uPAR) and the uPAR-associated protein (uPARAP/Endo180): membrane proteins engaged in matrix turnover during tissue remodeling

scientific article

The urokinase receptor and regulation of cell surface plasminogen activation.

scientific article published on December 1990

Urokinase receptor-associated protein (uPARAP) is expressed in connection with malignant as well as benign lesions of the human breast and occurs in specific populations of stromal cells

scientific article published on 01 April 2002

Urokinase-catalysed cleavage of the urokinase receptor requires an intact glycolipid anchor.

scientific article published in September 2001

uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion

scientific article

uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis

scientific article published in Nature Communications

uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV.

scientific article

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