List of works - Takafumi Suzuki

Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells

scientific article published on 03 October 2016

Author Correction: Nrf2 contributes to the weight gain of mice during space travel

scientific article published on 07 October 2020

Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response.

scientific article published on 2 November 2015

Deletion of the selenocysteine tRNA gene in macrophages and liver results in compensatory gene induction of cytoprotective enzymes by Nrf2.

scientific article published on 26 November 2007

Environmental pollutants and the immune response

scientific article published on 12 October 2020

Genetic analysis of cytoprotective functions supported by graded expression of Keap1

scientific article

Global downstream pathway analysis reveals a dependence of oncogenic NF-E2-related factor 2 mutation on the mTOR growth signaling pathway.

scientific article published on 9 November 2010

Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus.

scientific article published on 24 February 2017

Hyperactivation of Nrf2 leads to hypoplasia of bone in vivo.

scientific article published on 15 March 2018

Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system.

scientific article

Keap1 inhibition attenuates glomerulosclerosis.

scientific article published on 11 February 2014

Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth.

scientific article

Mitochondrial SKN-1/Nrf Mediates a Conserved Starvation Response ⬇️

scientific article published on October 3, 2012

Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap1

scientific article published on 01 July 2019

Molecular basis of the Keap1-Nrf2 system.

scientific article

Myeloid lineage-specific deletion of antioxidant system enhances tumor metastasis.

scientific article

Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia

scientific journal article

Nrf2 contributes to the weight gain of mice during space travel

scientific article published on 08 September 2020

Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production

scientific article published on 09 December 2020

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

scientific article

Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung.

scientific article

Nuclear factor E2-related factor 2 (NRF2) deficiency accelerates fast fibre type transition in soleus muscle during space flight

scientific article published on 24 June 2021

Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity

scientific article

Pi class glutathione S-transferase genes are regulated by Nrf 2 through an evolutionarily conserved regulatory element in zebrafish.

scientific article

Regulatory nexus of synthesis and degradation deciphers cellular Nrf2 expression levels.

scientific article published on 09 April 2013

Roles of Keap1-Nrf2 system in upper aerodigestive tract carcinogenesis

scientific article published on 18 December 2012

Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo.

scientific article published on 21 December 2010

The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin.

scientific article published on 21 November 2016

The distal sequence element of the selenocysteine tRNA gene is a tissue-dependent enhancer essential for mouse embryogenesis

scientific article

The novel Nrf2 inducer TFM-735 ameliorates experimental autoimmune encephalomyelitis in mice.

scientific article

The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1.

scientific article published on 24 November 2015

Validation of the multiple sensor mechanism of the Keap1-Nrf2 system ⬇️

scientific article published on June 23, 2012

p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming

scientific article

List of works by Takafumi Suzuki

Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells

Author Correction: Nrf2 contributes to the weight gain of mice during space travel

Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response.

Deletion of the selenocysteine tRNA gene in macrophages and liver results in compensatory gene induction of cytoprotective enzymes by Nrf2.

Environmental pollutants and the immune response

Genetic analysis of cytoprotective functions supported by graded expression of Keap1

Global downstream pathway analysis reveals a dependence of oncogenic NF-E2-related factor 2 mutation on the mTOR growth signaling pathway.

Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus.

Hyperactivation of Nrf2 leads to hypoplasia of bone in vivo.

Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system.

Keap1 inhibition attenuates glomerulosclerosis.

Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth.

Mitochondrial SKN-1/Nrf Mediates a Conserved Starvation Response ⬇️

Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap1

Molecular basis of the Keap1-Nrf2 system.

Myeloid lineage-specific deletion of antioxidant system enhances tumor metastasis.

Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia

Nrf2 contributes to the weight gain of mice during space travel

Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung.

Nuclear factor E2-related factor 2 (NRF2) deficiency accelerates fast fibre type transition in soleus muscle during space flight

Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity

Pi class glutathione S-transferase genes are regulated by Nrf 2 through an evolutionarily conserved regulatory element in zebrafish.

Regulatory nexus of synthesis and degradation deciphers cellular Nrf2 expression levels.

Roles of Keap1-Nrf2 system in upper aerodigestive tract carcinogenesis

Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo.

The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin.

The distal sequence element of the selenocysteine tRNA gene is a tissue-dependent enhancer essential for mouse embryogenesis

The novel Nrf2 inducer TFM-735 ameliorates experimental autoimmune encephalomyelitis in mice.

The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1.

Validation of the multiple sensor mechanism of the Keap1-Nrf2 system ⬇️

p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming