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List of works by Giuseppe Lazzarino

A new T677C mutation of the aspartoacylase gene encodes for a protein with no enzymatic activity.

scientific article

An ion-pairing high-performance liquid chromatographic method for the direct simultaneous determination of nucleotides, deoxynucleotides, nicotinic coenzymes, oxypurines, nucleosides, and bases in perchloric acid cell extracts.

scientific article published on November 1995

Antioxidant Therapies in Traumatic Brain Injury

scientific article published on 22 March 2020

Arctic adaptation in reindeer The energy saving of a hemoglobin

scientific article published on 01 April 1989

Assessment of metabolic brain damage and recovery following mild traumatic brain injury: a multicentre, proton magnetic resonance spectroscopic study in concussed patients

scientific article published on 23 August 2010

Biochemical analysis of the cerebrospinal fluid: evidence for catastrophic energy failure and oxidative damage preceding brain death in severe head injury: a case report

scientific article published in January 2005

Biochemical and neurochemical sequelae following mild traumatic brain injury: summary of experimental data and clinical implications

scientific article

Carnosine Decreases PMA-Induced Oxidative Stress and Inflammation in Murine Macrophages

scientific article published on 06 August 2019

Carnosine Prevents Aβ-Induced Oxidative Stress and Inflammation in Microglial Cells: A Key Role of TGF-β1

scientific article published on 17 January 2019

Cerebral oxidative stress and depression of energy metabolism correlate with severity of diffuse brain injury in rats

scientific article published in March 2005

Chromosomal 17p13.3 microdeletion unmasking recessive Canavan disease mutation

Clinical, biochemical and molecular diagnosis of a compound homozygote for the 254 bp deletion-8 bp insertion of the APRT gene suffering from severe renal failure.

scientific article published on 19 October 2006

Clobetasol promotes neuromuscular plasticity in mice after motoneuronal loss via sonic hedgehog signaling, immunomodulation and metabolic rebalancing

scientific article published on 16 June 2021

Cobalt-Protoporphyrin Improves Heart Function by Blunting Oxidative Stress and Restoring NO Synthase Equilibrium in an Animal Model of Experimental Diabetes

scientific article

Comparison of nitrite/nitrate concentration in human plasma and serum samples measured by the enzymatic batch Griess assay, ion-pairing HPLC and ion-trap GC–MS: The importance of a correct removal of proteins in the Griess assay

scientific article published on 15 February 2007

Cyanidin-3-O-beta-glucopyranoside protects myocardium and erythrocytes from oxygen radical-mediated damages

scientific article published in April 2003

Cyanidins: metabolism and biological properties

scientific article published on January 2004

Decrease in N-acetylaspartate following concussion may be coupled to decrease in creatine

scientific article published in July 2013

Determination of Boronophenylalanine in Biological Samples Using Precolumn o-Phthalaldehyde Derivatization and Reversed-Phase High-Performance Liquid Chromatography

scientific article published on 01 September 2000

Differentiation of human melanoma cells induced by cyanidin-3-O-beta-glucopyranoside

scientific article published on 27 September 2004

Discriminating formation of HNO from other reactive nitrogen oxide species

scientific article published on 21 November 2005

Effect of exogenous fructose-1,6-bisphosphate on glycolysis in the isolated perfused rat heart

scientific article published on 01 August 1991

Effectiveness of thrombolysis is associated with a time-dependent increase of malondialdehyde in peripheral blood of patients with acute myocardial infarction

scientific article published on 01 April 1993

Energy metabolism and lipid peroxidation of human erythrocytes as a function of increased oxidative stress

scientific article published on 01 February 2000

Evaluation of biochemical parameters in platelet concentrates stored in glucose solution

scientific article published on January 2007

Exogenous fructose-1,6-bisphosphate is a metabolizable substrate for the isolated normoxic rat heart

scientific article published on 01 May 1992

Extracellular N-acetylaspartate depletion in traumatic brain injury

scientific article published on 20 December 2005

Fructose-1,6-Bisphosphate Protects Hippocampal Rat Slices from NMDA Excitotoxicity ⬇️

scientific article published on 07 May 2019

Fusion or Fission: The Destiny of Mitochondria In Traumatic Brain Injury of Different Severities.

scientific article

Glucose ameliorates the metabolic profile and mitochondrial function of platelet concentrates during storage in autologous plasma

scientific article published on 13 April 2012

HPLC Analysis for the Clinical–Biochemical Diagnosis of Inborn Errors of Metabolism of Purines and Pyrimidines

scientific article published on 01 January 2011

High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury

scientific article published on 24 March 2008

Hypothesis of the postconcussive vulnerable brain: experimental evidence of its metabolic occurrence

scientific article published in July 2005

Increase of uric acid and purine compounds in biological fluids of multiple sclerosis patients

scientific article

Inhibiting metalloproteases with PD 166793 in heart failure: impact on cardiac remodeling and beyond.

scientific article published on January 2008

Inhibition of TLR4 Signaling Affects Mitochondrial Fitness and Overcomes Bortezomib Resistance in Myeloma Plasma Cells

scientific article published on 22 July 2020

Ion-Pairing High-Performance Liquid Chromatographic Method for the Detection of N-Acetylaspartate and N-Acetylglutamate in Cerebral Tissue Extracts

scientific article published on 01 January 2000

Is adenine phophorybosiltransferase deficiency a still underdiagnosed cause of urolithiasis and chronic renal failure? A report of two cases in a family with an uncommon novel mutation

scientific article published on 19 June 2008

Ischemia and reperfusion: effect of fructose-1,6-bisphosphate

scientific article published on January 1, 1992

L-DOPA preloading increases the uptake of borophenylalanine in C6 glioma rat model: a new strategy to improve BNCT efficacy.

scientific article

Low Molecular Weight Dextran Sulfate (ILB®) Administration Restores Brain Energy Metabolism Following Severe Traumatic Brain Injury in the Rat

scientific article published on 10 September 2020

Malondialdehyde is a biochemical marker of peroxidative damage in the isolated reperfused rat heart

scientific article published on 01 October 1992

Malondialdehyde production and ascorbate decrease are associated to the reperfusion of the isolated postischemic rat heart ⬇️

scientific article published on January 1, 1992

Metalloproteinase inhibitor counters high-energy phosphate depletion and AMP deaminase activity enhancing ventricular diastolic compliance in subacute heart failure

scientific article published on 25 January 2006

Microfluidics as a Novel Tool for Biological and Toxicological Assays in Drug Discovery Processes: Focus on Microchip Electrophoresis

scientific article published on 15 June 2020

Mitochondrial Functions, Energy Metabolism and Protein Glycosylation are Interconnected Processes Mediating Resistance to Bortezomib in Multiple Myeloma Cells

scientific article published on 30 April 2020

Modulation of circulating purines and pyrimidines by physical exercise in the horse

scientific article published on 08 October 2010

Modulation of peripheral markers of the serotoninergic system in healthy horses

scientific article published on 14 July 2010

New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity.

scientific article

Non-toxic engineered carbon nanodiamond concentrations induce oxidative/nitrosative stress, imbalance of energy metabolism, and mitochondrial dysfunction in microglial and alveolar basal epithelial cells.

scientific article published on 14 February 2018

Oxidant stress from nitric oxide synthase–3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load

Potentially neuroprotective gene modulation in an in vitro model of mild traumatic brain injury

scientific article

Pyruvate Dehydrogenase and Tricarboxylic Acid Cycle Enzymes Are Sensitive Targets of Traumatic Brain Injury Induced Metabolic Derangement

scientific article published on 16 November 2019

Receptor-mediated toxicity of human amylin fragment aggregated by short- and long-term incubations with copper ions

scientific article published on November 2016

Reply to: Comments on "Glucose ameliorates the metabolic profile and mitochondrial function of platelet concentrates during storage in autologous plasma".

scientific article

Serum Compounds of Energy Metabolism Impairment Are Related to Disability, Disease Course and Neuroimaging in Multiple Sclerosis.

scientific article published on 8 November 2016

Severity of experimental traumatic brain injury modulates changes in concentrations of cerebral free amino acids

scientific article published on 3 October 2016

Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism.

scientific article

Single-sample preparation for simultaneous cellular redox and energy state determination

scientific article

Sports-related concussion: ongoing debate

scientific article published on 15 March 2013

Sub-Toxic Human Amylin Fragment Concentrations Promote the Survival and Proliferation of SH-SY5Y Cells via the Release of VEGF and HspB5 from Endothelial RBE4 Cells ⬇️

article

Synthesis and antioxidant activity of new homocarnosine β-cyclodextrin conjugates

scientific article published on 21 January 2007

TEMPORAL WINDOW OF METABOLIC BRAIN VULNERABILITY TO CONCUSSION

scholarly article by Roberto Vagnozzi et al published June 2008 in Neurosurgery

Temporal window of metabolic brain vulnerability to concussions: mitochondrial-related impairment--part I.

scientific article published in August 2007

Temporal window of metabolic brain vulnerability to concussions: oxidative and nitrosative stresses--part II.

scientific article published in August 2007

The activation of metabolites of nitric oxide synthase by metals is both redox and oxygen dependent: a new feature of nitrogen oxide signaling

scientific article published on July 2006

The effect of holding live sea urchins (Evechinus chloroticus) in air prior to gonad removal on gonad adenine nucleotide profiles during storage at 4°C

scientific article published on 26 March 2013

The molecular mechanisms affecting N-acetylaspartate homeostasis following experimental graded traumatic brain injury

scientific article published on 24 March 2014

The pathophysiology of concussion

scientific article

The protective effect of cyclosporin A upon N-acetylaspartate and mitochondrial dysfunction following experimental diffuse traumatic brain injury

scientific article

Time dependence of plasma malondialdehyde, oxypurines, and nucleosides during incomplete cerebral ischemia in the rat.

scientific article published on December 1994

Transcriptomics of traumatic brain injury: gene expression and molecular pathways of different grades of insult in a rat organotypic hippocampal culture model

scientific article

Transient alterations of creatine, creatine phosphate, N-acetylaspartate and high-energy phosphates after mild traumatic brain injury in the rat.

scientific article published on 18 August 2009

Water- and Fat-Soluble Antioxidants in Human Seminal Plasma and Serum of Fertile Males.

scientific article

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