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List of works by Patrick Meraldi

A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators.

scientific article published in January 1998

Anti-angiogenic effects of crenolanib are mediated by mitotic modulation independently of PDGFR expression

scientific article published on 25 June 2019

Aurora kinases link chromosome segregation and cell division to cancer susceptibility

scientific article published on February 2004

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

scientific article

Bub1 regulates chromosome segregation in a kinetochore-independent manner

scientific article

Bub1-the zombie protein that CRISPR cannot kill

scientific article published on 08 March 2019

C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2

scientific article

CLASPs prevent irreversible multipolarity by ensuring spindle-pole resistance to traction forces during chromosome alignment.

scientific article published on 5 February 2012

CRL4(RBBP7) is required for efficient CENP-A deposition at centromeres.

scientific article published on 20 March 2015

Cell polarity-dependent centrosome separation in the C. elegans embryo

scientific article published on 23 October 2019

Centrosome age regulates kinetochore-microtubule stability and biases chromosome mis-segregation

scientific article published on 19 August 2015

Centrosome cohesion is regulated by a balance of kinase and phosphatase activities ⬇️

scientific article published on October 1, 2001

Centrosomes in spindle organization and chromosome segregation: a mechanistic view

scientific article

Combination of ruthenium(II)-arene complex [Ru(η6-p-cymene)Cl2(pta)] (RAPTA-C) and the epidermal growth factor receptor inhibitor erlotinib results in efficient angiostatic and antitumor activity

scientific article published on 22 February 2017

Complete microtubule-kinetochore occupancy favours the segregation of merotelic attachments.

scientific article

Coordinate regulation of the mother centriole component nlp by nek2 and plk1 protein kinases

scientific article

Double-trouble in mitosis caused by von Hippel-Lindau tumor-suppressor protein inactivation

scientific article published on 01 November 2009

Dynamics of CENP-N kinetochore binding during the cell cycle

scientific article

Effect of Cell Shape and Dimensionality on Spindle Orientation and Mitotic Timing

scientific article (publication date: 2013)

Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant

scientific article

Finding the middle ground: how kinetochores power chromosome congression.

scientific article

Human TPX2 is required for targeting Aurora-A kinase to the spindle

scientific article

Human chromokinesins promote chromosome congression and spindle microtubule dynamics during mitosis ⬇️

scientific article published on September 3, 2012

Identification of a Synergistic Multi-Drug Combination Active in Cancer Cells via the Prevention of Spindle Pole Clustering

scientific article published on 22 October 2019

Keeping kinetochores on track.

scientific article

Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases

scientific article

Kinetochore-generated pushing forces separate centrosomes during bipolar spindle assembly

scientific article published on February 2009

Kinetochores accelerate centrosome separation to ensure faithful chromosome segregation ⬇️

scientific article published on February 15, 2012

Location of Mutation in BRCA2 Gene and Survival in Patients with Ovarian Cancer.

scientific article published on 30 October 2017

Mechanisms of aneuploidy and its suppression by tumour suppressor proteins ⬇️

scientific article published on 08 March 2011

Mild replication stress causes chromosome mis-segregation via premature centriole disengagement

scientific article published on 08 August 2019

Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function

scientific article published in October 2017

Mitotic live-cell imaging at different timescales

scientific article published on 01 January 2018

Mitotic spindle (DIS)orientation and DISease: cause or consequence?

scientific article

Modulation of the Chromatin Phosphoproteome by the Haspin Protein Kinase

scientific article

Molecular control of kinetochore-microtubule dynamics and chromosome oscillations

scientific article

Nonautonomous movement of chromosomes in mitosis

scientific article published in October 2013

Phylogenetic and structural analysis of centromeric DNA and kinetochore proteins

scientific article

Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation

scientific journal article

Spindle-Length-Dependent HURP Localization Allows Centrosomes to Control Kinetochore-Fiber Plus-End Dynamics

scientific article published on 24 October 2019

Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex

scientific article

Symmetry Does not Come for Free: Cellular Mechanisms to Achieve a Symmetric Cell Division.

scientific article published on January 2017

TRAIP is a regulator of the spindle assembly checkpoint

scientific article published on 21 October 2014

The CCAN complex: Linking centromere specification to control of kinetochore–microtubule dynamics ⬇️

scientific article published on October 19, 2011

The CENP-A NAC/CAD kinetochore complex controls chromosome congression and spindle bipolarity

scientific article

The Elephant in the Room: The Role of Microtubules in Cancer

scientific article published on January 2017

The Ska complex promotes Aurora B activity to ensure chromosome biorientation.

scientific article published on 3 October 2016

The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation

scientific article

The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation

The spindle assembly checkpoint: clock or domino?

scientific article published on January 2011

Timing and checkpoints in the regulation of mitotic progression

scientific article

Two Ways to Get Mad at Kinetochores

scientific article published in December 2015

VHL loss causes spindle misorientation and chromosome instability.

scientific article

p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment

scientific article published on 30 September 2011

p37/UBXN2B regulates spindle orientation by limiting cortical NuMA recruitment via PP1/Repo-Man.

scientific article published on 8 December 2017

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