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List of works by Xianglin Shi

A Shope Fibroma virus PYRIN-only protein modulates the host immune response

journal article published in 2007

A critical role of PI-3K/Akt/JNKs pathway in benzo[a]pyrene diol-epoxide (B[a]PDE)-induced AP-1 transactivation in mouse epidermal Cl41 cells

scientific article published in May 2004

AKT1 amplification regulates cisplatin resistance in human lung cancer cells through the mammalian target of rapamycin/p70S6K1 pathway

scientific article

Accelerated tissue aging and increased oxidative stress in broiler chickens fed allopurinol

journal article published in 2001

Actions of a histone deacetylase inhibitor NSC3852 (5-nitroso-8-quinolinol) link reactive oxygen species to cell differentiation and apoptosis in MCF-7 human mammary tumor cells

journal article published in 2006

Activation of AP-1 through the MAP kinase pathway: a potential mechanism of the carcinogenic effect of arenediazonium ions

journal article published in 2000

Activation of Akt/GSK3β and Akt/Bcl-2 signaling pathways in nickel-transformed BEAS-2B cells

scientific article

Activation of Epidermal Growth Factor Receptor/p38/Hypoxia-inducible Factor-1α Is Pivotal for Angiogenesis and Tumorigenesis of Malignantly Transformed Cells Induced by Hexavalent Chromium

scientific article published on 25 May 2016

Activation of JNK and c-Jun is involved in glucose oxidase-mediated cell death of human lymphoma cells

scientific article published on 19 November 2009

Activation of JNK by vanadate induces a Fas-associated death domain (FADD)- dependent death of cerebellar granule progenitors in vitro ⬇️

journal article published in 2003

Activation of a PKC is required for vanadate-induced phosphorylation of protein kinase B (Akt), but not p70S6k in mouse epidermal JB6 cells

journal article published in 2004

Activation of activator protein-1 by reactive oxygen species associated with asbestos ⬇️

abstract published in 2000

Activation of androgen response element by cadmium: a potential mechanism for a carcinogenic effect of cadmium in the prostate ⬇️

journal article published in 2000

Activation of mitogen-activated protein kinase p38 and extracellular signal-regulated kinase is involved in glass fiber-induced tumor necrosis factor-alpha production in macrophages

journal article published in 2001

Alcohol-induced oxidative stress and cell responses

scientific article published on October 2006

An integrative genomic and proteomic approach to chemosensitivity prediction

journal article published in 2009

Antioxidant Activity of Lazaroid (U-75412E) and its Protective Effects Against Crystalline Silica-Induced Cytotoxicity ⬇️

scientific article published on March 1, 1998

Antioxidant activity of tetrandrine and its inhibition of quartz-induced lipid-peroxidation

journal article published in 1995

Antioxidant properties of (-)-epicatechin-3-gallate and its inhibition of Cr(VI)-induced DNA damage and Cr(IV)- or TPA-stimulated NF-kB activation

journal article published in 2000

Antioxidant properties of aspirin: characterization of the ability of aspirin to inhibit silica-induced lipid peroxidation, DNA damage, NF-KB activation, and TNF-alpha production

journal article published in 1999

Antioxidant properties of fruit and vegetable juices: more to the story than ascorbic acid ⬇️

journal article published in 2002

Antioxidant properties of pyrrolidine dithiocarbamate and its protection against Cr(VI)-induced DNA strand breakage ⬇️

journal article published in 2000

Antisense inhibition of silica-induced tumor necrosis factor in alveolar macrophages

journal article published in 1997

Apigenin induces apoptosis in human leukemia cells and exhibits anti-leukemic activity in vivo

scientific article published on 14 November 2011

Apigenin inhibits expression of vascular endothelial growth factor and angiogenesis in human lung cancer cells: implication of chemoprevention of lung cancer

scientific article published on 9 June 2005

Apigenin inhibits tumor angiogenesis through decreasing HIF-1alpha and VEGF expression

scientific article published on 27 October 2006

Apigenin suppresses migration and invasion of transformed cells through down-regulation of C-X-C chemokine receptor 4 expression

scientific article

Arsenic activates NADPH oxidase through CDC42 and their involvement in actin filament remodeling and cell motility in endothelial cells ⬇️

abstract published in 2004

Arsenic and chromium in drinking water promote tumorigenesis in a mouse colitis-associated colorectal cancer model and the potential mechanism is ROS-mediated Wnt/β-catenin signaling pathway

scientific article published on 19 April 2012

Arsenic induced an increase in endothelial cell permeability: involvement of cytoskeleton signaling ⬇️

abstract published in 2008

Arsenic inhibits neurite outgrowth by inhibiting the LKB1-AMPK signaling pathway

scientific article

Arsenic promotes angiogenesis in vitro via a heme oxygenase-1-dependent mechanism

scientific article published on 18 January 2010

Arsenic-induced NFkB transactivation through Erks- and JNKs-dependent pathways in mouse epidermal JB6 cells

journal article published in 2001

Arsenite causes DNA damage in keratinocytes via generation of hydroxyl radicals

journal article published in 2004

Arsenite induces HIF-1a and VEGF through PI3K, Akt and reactive oxygen species in DU145 human prostate carcinoma cells

journal article published in 2004

Arsenite induces a cell stress-response gene, RTP801, through reactive oxygen species and transcription factors Elk-1 and CCAAT/enhancer-binding protein

journal article published in 2005

Arsenite induces p70S6K1 activation and HIF-1alpha expression in prostate cancer cells

journal article published in 2004

Arsenite modulation of the integrity of actin filaments and the increase in cell motility may be mediated through CDC42 ⬇️

conference abstract published in 2002

Arsenite stabilizes HIF-1α protein through p85α-mediated up-regulation of inducible Hsp70 protein expression

scientific article published on 12 September 2010

Arsenite-induced Cdc25C degradation is through the KEN-box and ubiquitin-proteasome pathway ⬇️

journal article published in 2002

As(III) transcriptionally activates the gadd45a gene via the formation of H2O2

journal article published in 2006

Asbestos induces AP-1 activation in cell culture and transgenic mice

abstract published in 1999

Asbestos induces activator protein-1 transactivation in transgenic mice ⬇️

journal article published in 1999

Autophagy is a cell self-protective mechanism against arsenic-induced cell transformation

scientific article

Autophagy is a protective response to ethanol neurotoxicity

scientific article

Benzo(a)pyrene-caused increased G(1)-S transition requires the activation of c-Jun through p53-dependent PI-3K/Akt/ERK pathway in human embryo lung fibroblasts

journal article published in 2008

Benzo[a]pyrene-3,6-dione inhibited VEGF expression through inducing HIF-1alpha degradation

scientific article published on 9 April 2007

Blackberry extract inhibits UVB-induced oxidative damage and inflammation through MAP kinases and NF-κB signaling pathways in SKH-1 mice skin

scientific article

Blackberry extracts inhibit activating protein 1 activation and cell transformation by perturbing the mitogenic signaling pathway

journal article published in 2004

Brain-derived neurotrophic factor suppresses tunicamycin-induced upregulation of CHOP in neurons

scientific article

C8-arylguanine and C8-aruladenine formation in calf thymus DNA from arenediazonium ions

journal article published in 1999

Cadmium induces autophagy through ROS-dependent activation of the LKB1-AMPK signaling in skin epidermal cells

scientific article

Cadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/β-catenin signaling

scientific article

Cadmium induces intracellular Ca2+- and H2O2-dependent apoptosis through JNK- and p53-mediated pathways in skin epidermal cell line

scientific article

Calpain contributes to silica-induced IkB-a degradation and nuclear factor-kB activation

journal article published in 1997

Cancer Stem-Like Cells Accumulated in Nickel-Induced Malignant Transformation

scientific article

Cancer stem cells in the mechanism of metal carcinogenesis

scientific article published on January 1, 2012

Carcinogenic effect of nickel compounds

scientific article

Carcinogenic metals and NF-kB activation

journal article published in 2001

Catalytic asymmetric Petasis reactions of vinylboronates

scientific article

Cdc42 regulates arsenic-induced NADPH oxidase activation and cell migration through actin filament reorganization

journal article published in 2005

Cdc42-Dependent Activation of NADPH Oxidase Is Involved in Ethanol-Induced Neuronal Oxidative Stress ⬇️

scientific article published on May 25, 2012

Cell apoptosis induced by carcinogenic metals

journal article published in 2001

Cell cycle alterations of human embryo lung fibroblasts induced by benzo(a)pyrene is positively regulated by cyclin D1 and CDK4

scientific article published in July 2008

Cellular delivery of oligonucleotides by synthetic import peptide carrier

journal article published in 1997

Cellular mechanisms of the cytotoxic effects of the zearalenone metabolites α-zearalenol and β-zearalenol on RAW264.7 macrophages

scientific article published on 31 January 2013

Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation

scientific article

Changes in bronchoalveolar lavage indices associated with radiographic classification in coal miners

journal article published in 2000

Characterization of an alternatively spliced GADD45 alpha, GADD45 alpha 1 isoform, inarsenic-treated epithelial cells

journal article published in 2009

Chemopreventive activity of parthenolide against UVB-induced skin cancer and its mechanisms

journal article published in 2004

Chromium (VI) induces insulin resistance in 3T3-L1 adipocytes through elevated reactive oxygen species generation

scientific article

Chronic ethanol exposure enhances the aggressiveness of breast cancer: the role of p38γ

scientific article

Chronic insulin treatment causes insulin resistance in 3T3-L1 adipocytes through oxidative stress

scientific article

Chronic plus binge ethanol exposure causes more severe pancreatic injury and inflammation

scientific article published on 15 August 2016

Cobalt-mediated generation of reactive oxygen species and its possible mechanism

journal article published in 1998

Combining drosophila melanogaster somatic-mutation-recombination and electron-spin-resonance-spectroscopy data to interpret epidemiologic observations on chromium carcinogenicity

journal article published in 2001

Concentrations of arsenic, chromium, and nickel in toenail samples from Appalachian Kentucky residents

scientific article

Conference overview: molecular mechanisms of metal toxicity and carcinogenesis

journal article published in 2005

Confirmation of gene expression-based prediction of survival in non-small cell lung cancer

journal article published in 2008

Constitutive activation of epidermal growth factor receptor promotes tumorigenesis of Cr(VI)-transformed cells through decreased reactive oxygen species and apoptosis resistance development

scientific article

Continuously generated H2O2 stimulates the proliferation and osteoblastic differentiation of human periodontal ligament fibroblasts

scientific article published in April 2012

Contrasting roles of NF-kB and JNK in arsenite-induced p53-independent expression of GADD45alpha ⬇️

journal article published in 2001

Cr(III)-mediated hydroxyl radical generation via Haber-Weiss cycle

journal article published in 1998

Cr(IV) causes activation of nuclear transcription factor-kappa B, DNA strand breaks and dG hydroxylation via free radical reactions

journal article published in 1999

Cr(VI) increases tyrosine phosphorylation through reactive oxygen species-mediated reactions

journal article published in 2001

Cr(VI) induces cell growth arrest through hydrogen peroxide-mediated reactions

journal article published in 2001

Cr(VI) induces mitochondrial-mediated and caspase-dependent apoptosis through reactive oxygen species-mediated p53 activation in JB6 Cl41 cells

scientific article (publication date: June 2010)

Critical role of fiber length in the bioactivity and cytotoxicity of glass fibers ⬇️

conference proceedings item published in 2000

Critical role of fiber length in the bioactivity and cytotoxicity of glass fibers ⬇️

abstract published in 2000

Critical role of glass fiber length in TNF-alpha production and transcription factor activation in macrophages

journal article published in 1999

Critical role of poly(ADP-ribose) polymerase-1 in modulating the mode of cell death caused by continuous oxidative stress

scientific article

Cyanidin-3-Glucoside inhibits ethanol-induced invasion of breast cancer cells overexpressing ErbB2 ⬇️

scientific article published on October 29, 2010

Cyanidin-3-glucoside inhibits UVB-induced oxidative damage and inflammation by regulating MAP kinase and NF-κB signaling pathways in SKH-1 hairless mice skin

scientific article

Cyanidin-3-glucoside reverses ethanol-induced inhibition of neurite outgrowth: role of glycogen synthase kinase 3 beta

journal article published in 2009

Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity

journal article published in 2006

Cyanidin‐3‐glucoside ameliorates ethanol neurotoxicity in the developing brain ⬇️

scientific article published on June 10, 2011

Cytoplasm-localized SIRT1 enhances apoptosis

scientific article published on October 2007

DNA cleavage by the photolysis of cyclopentadienyl metal complexes: mechanistic studies and sequence selectivity of strand scission by CpW(CO)3CH3

journal article published in 2005

Deficiency in Ikk beta gene enhances arsenic-induced gadd45alpha expression

journal article published in 2005

Detection of hydroxyl radicals in aqueous suspensions of fresh silica dust and its implication to lipid peroxidation in silicosis ⬇️

conference proceedings item published in 1990

Dietary flavonoids as cancer prevention agents

scientific article published on January 2011

Different roles of ROS and Nrf2 in Cr(VI)-induced inflammatory responses in normal and Cr(VI)-transformed cells

scientific article published on 25 July 2016

Differential role of hydrogen peroxide in UV-induced signal transduction

journal article published in 2002

Diseases caused by silica: mechanisms of injury and disease development

journal article published in 2002

Do silicon-oxygen radicals play a role in the quartz-induced hemolysis and fibrogenicity? ⬇️

conference proceedings item published in 1990

Double-Stranded RNA-Dependent Protein Kinase Regulates the Motility of Breast Cancer Cells ⬇️

scientific article published on October 24, 2012

Downregulation of cyclin D1-CDK4 protein in human embryonic lung fibroblasts (HELF) induced by silica is mediated through the ERK and JNK pathway

scientific article published on 25 July 2008

Dual Roles of Oxidative Stress in Metal Carcinogenesis

scientific article published in January 2017

ERKs activation and calcium signaling are both required for VEGF induction by vanadium in mouse epidermal Cl41 cells

scientific article published on November 2005

Effect of Cr(VI) exposure on sperm quality: human and animal studies

journal article published in 2001

Effect of antioxidant protection by p-coumaric acid on low-density lipoprotein cholesterol oxidation

journal article published in 2000

Effect of stainless steel manual metal arc welding fume on free radical production, DNA damage, and apoptosis induction

journal article published in 2005

Effects of soluble and insoluble fractions of a stainless steel manual metal arc welding fume on free radical production and lung injury and inflammation ⬇️

abstract published in 2003

Effects of stainless steel manual metal arc welding fumes on DNA damage and apoptosis induction in vitro and in vivo ⬇️

abstract published in 2004

Effects of the lung carcinogen silica on cyclooxygenase-2 and prostaglandin E2 expression in RAW 264.7 cells ⬇️

conference abstract published in 2002

Effects of welding fumes on lung injury and inflammation: the possible role of free radical production ⬇️

abstract published in 2002

Efficacy of taurine and hypotaurine as hydroxyl radical scavengers ⬇️

abstract published in 1998

Efficacy of taurine based compounds as hydroxyl radical scavengers in silica induced peroxidation ⬇️

scientific article published on September 1, 1997

Enhanced Generation of Free Radicals from Phagocytes Induced by Mineral Dusts ⬇️

scientific article published on April 1, 1992

Environmental health research in the post-genome era: new fields, new challenges, and new opportunities

journal article published in 2005

Epidermal growth factor up-regulates the transcription of mouse lon homology ATP-dependent protease through extracellular signal-regulated protein kinase- and phosphatidylinositol-3-kinase-dependent pathways

scientific article published on October 2002

Epigenetic targets of arsenic: emphasis on epigenetic modifications during carcinogenesis

scientific article

ErbB2 and p38γ MAPK mediate alcohol-induced increase in breast cancer stem cells and metastasis

scientific article

Essential role of PI-3K, ERKs and calcium signal pathways in nickel-induced VEGF expression

scientific article published on November 2005

Essential roles of ERKs and p38K in up-regulation of GST A1 expression by Maotai content in human hepatoma cell line Hep3B.

scientific article published on 20 June 2006

Essiac tea: scavenging of reactive oxygen species and effects on DNA damage

journal article published in 2006

Ethanol Disrupts Vascular Endothelial Barrier: Implication in Cancer Metastasis ⬇️

scientific article published on February 13, 2012

Ethanol Induces Endoplasmic Reticulum Stress in the Developing Brain ⬇️

scientific article published on May 20, 2011

Ethanol enhances arsenic-induced cyclooxygenase-2 expression via both NFAT and NF-κB signalings in colorectal cancer cells

scientific article

Ethanol enhances the interaction of breast cancer cells over-expressing ErbB2 with fibronectin

scientific article

Ethanol enhances tumor angiogenesis in vitro induced by low-dose arsenic in colon cancer cells through hypoxia-inducible factor 1 alpha pathway

scientific article published on 7 August 2012

Ethanol promotes endoplasmic reticulum stress-induced neuronal death: involvement of oxidative stress

scientific article

Ethanol promotes mammary tumor growth and angiogenesis: the involvement of chemoattractant factor MCP-1 ⬇️

scientific article published on December 9, 2011

Free radical generation by wood smoke particles and in vitro DNA damage ⬇️

abstract published in 1999

Free radical scavenging, DNA protection, and inhibition of lipid peroxidation mediated by uric acid ⬇️

journal article published in 2005

Free radical-mediated transgene inactivation of macrophages by endotoxin

journal article published in 2000

Freshly fractured crystalline silica induces activator protein-1 activation through ERKs and p38 MAPK

journal article published in 1999

Fzrl/Cdh links to redox-independent Cdc25C ubiquitination and degradation induced by arsenic

abstract published in 2004

GADD45 is an oxidative stress response protein ⬇️

abstract published in 2003

GSK3β signaling is involved in ultraviolet B-induced activation of autophagy in epidermal cells ⬇️

scientific article published on September 5, 2012

Gene expression profile in response to chromium-induced cell stress in A549 cells

journal article published in 2001

Generation of Free Radicals in Reactions of Ni (II)-thiol

publication published in 1993

Generation of free radicals from phagocytes induced by occupational minerals ⬇️

abstract published in 1992

Generation of metal-induced reactive oxygen species by residual oil fly ash ⬇️

abstract published in 2002

Generation of reactive oxygen species by quartz particles and its implication for cellular damage

journal article published in 1995

Generation of reactive oxygen species in the enzymatic reduction of PbCrO4 and related DNA damage

journal article published in 2002

Genetic and cellular mechanisms in chromium and nickel carcinogenesis considering epidemiologic findings

scientific article published on January 2004

Hemoglobin potentiates the generation of reactive oxygen species by alveolar macrophages ⬇️

conference abstract published in 1999

Hemoglobin potentiates the production of reactive oxygen species by alveolar macrophages

journal article published in 2000

Hexavalent chromium induces malignant transformation of human lung bronchial epithelial cells via ROS-dependent activation of miR-21-PDCD4 signaling

scientific article published on 13 June 2016

High-efficiency gene transfection of macrophages by lipoplexes

journal article published in 2000

Hydrogen peroxide formation and actin filament reorganization by Cdc42 are essential for ethanol-induced in vitro angiogenesis ⬇️

journal article published in 2003

Hydrogen peroxide formation and actin filament reorganization by Cdc42 are essential for ethanol-induced in vitro angiogenesis.

scientific article published in December 2007

Hydrogen peroxide mediates activation of nuclear factor of activated T cells (NFAT) by nickel subsulfide ⬇️

journal article published in 2001

Hydroxytyrosol protects against oxidative damage by simultaneous activation of mitochondrial biogenesis and phase II detoxifying enzyme systems in retinal pigment epithelial cells

scientific article

IKK[beta] deficiency causes oxidative stress and prolonged JNK activation induced by arsenic

conference abstract published in 2003

ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling

journal article published in 2005

Identification of a critical site in Wld(s): essential for Nmnat enzyme activity and axon-protective function

scientific article published on 15 December 2006

Impairment of NF-kB activation and modulation of gene expression by calpastatin

journal article published in 2000

In vivo bioassays of acute asbestosis and its correlation with ESR spectroscopy and imaging in redox status

journal article published in 2002

In vivo reduction of chromium (VI) and its related free radical generation

journal article published in 2001

Incorporation of an internal ribosome entry site-dependent mechanism in arsenic-induced GADD45alpha expression

journal article published in 2007

Individualized survival and treatment response predictions for breast cancers using phospho-EGFR, phospho-ER, phospho-HER2/neu, phospho-IGF-IR/In, phospho-MAPK, and phospho-p70S6K proteins

journal article published in 2007

Individualized survival and treatment response predictions in breast cancer patients: involvements of phospho-EGFR and phospho-Her2/neu proteins

journal article published in 2008

Induction of TNFalpha in macrophages by vanadate is dependent on activation of transcription factor NF-KB and free radical reactions

journal article published in 1999

Induction of a cell stress response gene RTP801 by DNA damaging agent methyl methanesulfate through CCAA/enhancer binding protein

journal article published in 2005

Induction of activator protein-1 through reactive oxygen species by crystalline silica in JB6 cells ⬇️

journal article published in 2001

Induction of apoptosis in human leukemia cells by grape seed extract occurs via activation of c-Jun NH2-terminal kinase

scientific article

Induction of miR-21-PDCD4 signaling by UVB in JB6 cells involves ROS-mediated MAPK pathways

journal article published in 2013

Induction of miR-21-PDCD4 signaling by tungsten carbide-cobalt nanoparticles in JB6 cells involves ROS-mediated MAPK pathways

journal article published in 2013

Inhibition of AP-1 and MAPK signaling and activation of Nrf2/ARE pathway by quercitrin

journal article published in 2010

Inhibition of AP-1 and neoplastic transformation by fresh apple peel extract

journal article published in 2004

Inhibition of NF-kappa B stabilizes gadd45 alpha mRNA

journal article published in 2005

Inhibition of benzo(a)pyrene-induced cell cycle progression by all-trans retinoic acid partly through cyclin D1/E2F-1 pathway in human embryo lung fibroblasts

scientific article published on 6 January 2006

Inhibition of endotoxin-induced lung inflammation by interleukin-10 gene transfer in mice

journal article published in 2000

Inhibitor of nuclear factor kB kinase deficiency enhances oxidative stress and prolongs c-Jun NH2-terminal kinase activation induced by arsenic ⬇️

journal article published in 2003

Interaction between ERK and GSK3beta mediates basic fibroblast growth factor-induced apoptosis in SK-N-MC neuroblastoma cells

scientific article

Interleukin-10-mediated Inhibition of free radical generation in macrophages

journal article published in 2001

Intracellular signal transduction of cells in response to carcinogenic metals

journal article published in 2002

Intratracheal amiodarone administration to F344 rats causes acute damage to airway and parenchymal cells: the possible role of free radical generation ⬇️

abstract published in 2001

Intratracheal amiodarone administration to F344 rats directly damages lung airway and parenchymal cells ⬇️

scientific article published on April 15, 2003

Involvement of 5'-flanking kB-like sites within bcl-x gene in silica-induced bcl-x expression ⬇️

journal article published in 1999

Involvement of Erks activation in cadmium-induced AP-1 transactivation in vitro and in vivo

journal article published in 2001

Involvement of NF-kappaB in silica-induced cyclooxygenase II gene expression in rat alveolar macrophages

journal article published in 1997

Involvement of hydrogen peroxide in asbestos-induced NFAT activation

journal article published in 2002

Involvement of vanadate-mediated reactive oxygen species in the activation of transcription factor AP-1 ⬇️

conference abstract published in 1999

Iron oxide nanoparticles induce human microvascular endothelial cell permeability through reactive oxygen species production and microtubule remodeling

journal article published in 2009

JNK1 activation predicts the prognostic outcome of the human hepatocellular carcinoma

journal article published in 2009

Lipoamide or lipoic acid stimulates mitochondrial biogenesis in 3T3‐L1 adipocytes via the endothelial NO synthase‐cGMP‐protein kinase G signalling pathway ⬇️

scientific article published on March 1, 2011

Lung cancer-associated JmjC domain protein mdig suppresses formation of tri-methyl lysine 9 of histone H3

journal article published in 2009

Luteolin and chrysin differentially inhibit cyclooxygenase-2 expression and scavenge reactive oxygen species but similarly inhibit prostaglandin-E2 formation in RAW 264.7 cells

journal article published in 2006

Luteolin inhibits Cr(VI)-induced malignant cell transformation of human lung epithelial cells by targeting ROS mediated multiple cell signaling pathways

scientific article published on 23 October 2014

Luteolin inhibits human prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis

scientific article

MAPKs mediate S phase arrest induced by vanadate through a p53-dependent pathway in mouse epidermal C141 cells

journal article published in 2002

MMP-2 mediates ethanol-induced invasion of mammary epithelial cells over-expressing ErbB2.

scientific article published in July 2006

Metal composition and solubility determine lung toxicity induced by residual oil fly ash collected from different sites within a power plant

journal article published in 2004

Metal-induced oxidative stress and cellular responses ⬇️

abstract published in 2006

Metal-induced oxidative stress and signal transduction

journal article published in 2004

Metal-induced toxicity, carcinogenesis, mechanisms and cellular responses

journal article published in 2004

Metallic nickel nano- and fine particles induce JB6 cell apoptosis through a caspase-8/AIF mediated cytochrome c-independent pathway

journal article published in 2009

Metallic nickel particles induce cell apoptosis through a caspase-8/AIF-mediated cytochrome c-independent pathway ⬇️

abstract published in 2009

Metals, metalloids, and cancer

chapter published in 2004

Microarray profiling in breast cancer patients

chapter published in 2008

Molecular activation of activator protein-1 in silica and asbestos-induced carcinogenesis

journal article published in 2000

Molecular mechanism of Cr(VI)-induced carcinogenesis

conference abstract published in 2000

Molecular mechanism of tumor necrosis factor-alpha production in 1-->3-B-glucan (zymosan)-activated macrophages

journal article published in 2001

Molecular mechanisms of Cr(VI)-induced carcinogenesis

journal article published in 2002

Molecular mechanisms of arsenic carcinogenesis

journal article published in 2004

Molecular mechanisms of metal toxicity and carcinogenesis

journal article published in 2001

Molecular mechanisms of metal toxicity and carcinogenesis

journal article published in 2004

Molecular targeting of nuclear transcriptional regulators

chapter published in 2000

Mycotoxin zearalenone induces AIF- and ROS-mediated cell death through p53- and MAPK-dependent signaling pathways in RAW264.7 macrophages

scientific article

NADPH oxidase 4 mediates insulin-stimulated HIF-1α and VEGF expression, and angiogenesis in vitro

scientific article

NADPH oxidase activation is required in reactive oxygen species generation and cell transformation induced by hexavalent chromium

scientific article

NF-kB, a pivotal transcription factor in silica-induced diseases

journal article published in 2002

NF-kappaB prevents cells from undergoing Cr(VI)-induced apoptosis

journal article published in 2004

New Developments in Mechanisms of Prostate Cancer Progression

scientific article published on 10 September 2018

New insights into the role of nuclear factor-KB, a ubiquitous transcription factor in the initiation of diseases ⬇️

journal article published in 1999

New insights into the role of nuclear factor-kB in cell growth regulation

journal article published in 2001

New perspectives in arsenic-induced cell signal transduction

journal article published in 2003

Nickel compounds act through phosphatidylinositol-3-kinase/Akt-dependent, p70(S6k)-independent pathway to induce hypoxia inducible factor transactivation and Cap43 expression in mouse epidermal Cl41 cells

scientific article published on January 2004

Nickel-induced down-regulation of ΔNp63 and its role in the proliferation of keratinocytes

scientific article

Nitric oxide inhibits HIV tat-induced NF-kB activation

journal article published in 1999

Nucleolin links to arsenic-induced stabilization of GADD5alpha mRNA

journal article published in 2006

Occupational toxicology of nickel and nickel compounds

journal article published in 2009

On the mechanism of Cr (VI)-induced carcinogenesis: dose dependence of uptake and cellular responses

journal article published in 2001

On the role of hydroxyl radical and the effect of tetrandrine on nuclear factor-kappaB activation by phorbol 12-myristate-13- acetate ⬇️

journal article published in 2000

One-electron reduction of chromium(VI) by alpha-lipoic acid and related hydroxyl radical generation, dG hydroxylation and nuclear transcription factor-kB activation

journal article published in 1997

One-electron reduction of vanadium (V) by flavoenzymes/NADPH

journal article published in 1993

Opposite effect of NF-kB and c-Jun N-terminal kinase on p53-independent GADD45 induction by arsenite

journal article published in 2001

Over-expression of erbB2 enhances ethanol-stimulated intracellular signaling and invasion of human mammary epithelial and breast cancer cells

conference abstract published in 2003

Overexpression of ErbB2 enhances ethanol-stimulated intracellular signaling and invasion of human mammary epithelial and breast cancer cells in vitro

journal article published in 2003

Overexpression of cyclin D1-CDK4 in silica-induced transformed cells is due to activation of ERKs, JNKs/AP-1 pathway

scientific article published on 25 August 2005

Overexpression of glycogen synthase kinase 3beta sensitizes neuronal cells to ethanol toxicity

scientific article

Oxidative mechanism of arsenic toxicity and carcinogenesis

journal article published in 2004

Oxidative stress and chromium(VI) carcinogenesis

scientific article published on January 2008

Oxidative stress and metal carcinogenesis

scientific article published on 15 June 2012

Oxidative stress in acute silicosis: correlation with toxicity and oxidative stress ⬇️

conference abstract published in 2006

Oxygen radical-mediated pulmonary toxicity induced by some cationic liposomes

journal article published in 2000

Oxygen/nitrogen radicals

book published in 2004

PI-3K and Akt are mediators of AP-1 induction by 5-MCDE in mouse epidermal Cl41 cells

scientific article

PI-3K/Akt pathway-dependent cyclin D1 expression is responsible for arsenite-induced human keratinocyte transformation

scientific article

PKC phosphorylation increases the ability of AFAP-110 to cross-link action filaments

journal article published in 2002

Participation of MAP kinase p38 and IkB kinase in chromium (VI)-induced NF-kB and AP-1 activation ⬇️

journal article published in 2000

PbCrO4 mediates cellular responses via reactive oxygen species

journal article published in 2004

Perfluorooctane sulfonate (PFOS) induces reactive oxygen species (ROS) production in human microvascular endothelial cells: role in endothelial permeability

journal article published in 2010

Phosphatidylinositol 3-kinase signaling is involved in neurogenesis during Xenopus embryonic development

scientific article

Phosphatidylinositol 3-kinase/Akt positively regulates fas (CD95)-mediated apoptosis in epidermal Cl41 cells

journal article published in 2006

Phosphatidylinositol-3 kinase/Akt/p70S6K/AP-1 signaling pathway mediated benzo(a)pyrene-induced cell cycle alternation via cell cycle regulatory proteins in human embryo lung fibroblasts.

scientific article published on 21 February 2007

Population-based molecular prognosis of breast cancer by transcriptional profiling

journal article published in 2007

Predicting cancer drug response by protoeomic profiling

journal article published in 2006

Predisposing factors in occupational lung cancer: inorganic minerals and chromium ⬇️

journal article published in 2000

Preface

scientific article (publication date: 2004)

Preface (Molecular Mechanisms of Metal Toxicity and Carcinogenesis)

publication published in 2001

Preface (The 3rd International Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis)

journal article published in 2005

Preface - special issue on environmental toxicology of metals and metalloids

journal article published in 2003

Prevention of Polyphenols Against Carcinogenesis Induced by Environmental Carcinogens

scientific article

Progress and prospects of reactive oxygen species in metal carcinogenesis

scientific article

Protection from Cr(VI)-induced malignant cell transformation and tumorigenesis of Cr(VI)-transformed cells by luteolin through Nrf2 signaling

scientific article

Protection of DNA and cellular membranes from reactive oxygen species mediated damage by uric acid ⬇️

abstract published in 2003

Protective roles of NF-kB for chromium (VI)-induced cytotoxicity is revealed by expression of IkB kinase-B mutant ⬇️

journal article published in 2002

Quercetin induces tumor-selective apoptosis through downregulation of Mcl-1 and activation of Bax.

scientific article

Quercetin inhibits Cr(VI)-induced malignant cell transformation by targeting miR-21-PDCD4 signaling pathway

scientific article published on 17 June 2016

Quercetin inhibits angiogenesis mediated human prostate tumor growth by targeting VEGFR- 2 regulated AKT/mTOR/P70S6K signaling pathways

scientific article

Quercitrin protects skin from UVB-induced oxidative damage

scientific article published on 29 March 2013

RETRACTED ARTICLE: Oncogenic transformation of human lung bronchial epithelial cells induced by arsenic involves ROS-dependent activation of STAT3-miR-21-PDCD4 mechanism

retracted scholarly article

RETRACTED: Antioncogenic and Oncogenic Properties of Nrf2 in Arsenic-induced Carcinogenesis

retracted article

RETRACTED: Nrf2/p62 signaling in apoptosis resistance and its role in cadmium-induced carcinogenesis

retracted article

RETRACTED: Nuclear factor erythroid 2-related factor 2 enhances carcinogenesis by suppressing apoptosis and promoting autophagy in nickel-transformed cells

retracted article

Rapid and sensitive assay of tumor necrosis factor-x gene transcription

journal article published in 2001

Reactive Oxygen Species and Silica-induced Carcinogenesis

book or book chapter published in 2001

Reactive oxygen species and molecular mechanism of silica-induced lung injury ⬇️

journal article published in 2001

Reactive oxygen species and silica-induced carcinogenesis

journal article published in 1998

Reactive oxygen species in the aerobic decomposition of sodium hydroxymethanesulfinate

journal article published in 1999

Reactive oxygen species mediate Cr(VI)-induced carcinogenesis through PI3K/AKT-dependent activation of GSK-3β/β-catenin signaling

scientific article

Reactive oxygen species mediate arsenic induced cell transformation and tumorigenesis through Wnt/β-catenin pathway in human colorectal adenocarcinoma DLD1 cells

scientific article

Reactive oxygen species regulate insulin-induced VEGF and HIF-1alpha expression through the activation of p70S6K1 in human prostate cancer cells

scientific article published on 13 June 2006

Reactive oxygen species-activated Akt/ASK1/p38 signaling pathway in nickel compound-induced apoptosis in BEAS 2B cells

journal article published in 2010

Reactive oxygen species: their relation to pneumoconiosis and carcinogenesis

journal article published in 1998

Reactivity of free radicals on hydroxylated quartz surface and its implications for pathogenicity of silicas: experimental and quantum mechanical study ⬇️

journal article published in 2001

Redox-dependent regulation of interleukin-8 by tumor necrosis factor-alpha in lung epithelial cells ⬇️

journal article published in 1999

Reduced reactive oxygen species-generating capacity contributes to the enhanced cell growth of arsenic-transformed epithelial cells

journal article published in 2010

Reduction of carcinogenic chromium(vi) on the skin of living rats ⬇️

scientific article published on October 1, 1997

Reduction of chromium(VI) and its relationship to carcinogenesis

journal article published in 1999

Regulation of Fas (CD95)-induced apoptosis by nuclear factor-KB and tumor necrosis factor- alpha in macrophages

journal article published in 2002

Regulation of Fas (CD95)-induced apoptotic and necrotic cell death by reactive oxygen species in macrophages

journal article published in 2005

Regulation of a cell type-specific silencer in the human iInterleukin-3 gene promoter by the transcription factor YY1 and an AP2 sequence-recognizing factor ⬇️

journal article published in 1999

Regulation of angiogenesis and tumor growth by p110 alpha and AKT1 via VEGF expression

journal article published in 2006

Resveratrol scavenges reactive oxygen species and effects radical-induced cellular responses

journal article published in 2003

Retracted: 3, 3'-Diindolylmethane Exhibits Antileukemic Activity In Vitro and In Vivo through a Akt-Dependent Process

retracted article

Role of MCP-1 in alcohol-induced aggressiveness of colorectal cancer cells

scientific article

Role of PI3K/AKT/mTOR signaling in G1 cell cycle progression in human ovarian cancer cells

conference abstract published in 2003

Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer

scientific article published in October 2003

Role of hydroxyl radical in silica-induced NF-kappa B activation in macrophages ⬇️

scientific article published on January 1, 1998

Role of metal-induced reactive oxygen species generation in lung responses caused by residual oil fly ash ⬇️

journal article published in 2003

Role of molecular oxygen in the generation of hydroxyl and superoxide anion radicals during enzymatic Cr(VI) reduction and its implication to Cr(VI)-induced carcinogenesis ⬇️

journal article published in 2000

Role of neutrophil apoptosis in vanadium-induced pulmonary inflammation in mice ⬇️

journal article published in 2002

Role of reactive oxygen species and Cr(VI) in Ras-mediated signal transduction

journal article published in 2004

Role of reactive oxygen species and MAPKs in vanadate-induced G2/M phase arrest ⬇️

scientific article published on May 15, 2003

Role of reactive oxygen species and p53 in chromium(VI)-induced apoptosis ⬇️

journal article published in 1999

Role of reactive oxygen species in arsenic-induced transformation of human lung bronchial epithelial (BEAS-2B) cells

scientific article

Role of transcription factor NF-KB in asbestos-induced TNF-alpha response from macrophages

journal article published in 1999

Roles of the ERK, JNK/AP‐1/cyclin D1–CDK4 pathway in silica‐induced cell cycle changes in human embryo lung fibroblast cells ⬇️

scientific article published on July 1, 2011

SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B

scientific article

Scavenging of superoxide anion radical by chaparral

journal article published in 1999

Selection of nutrients for prevention or amelioration of lead-induced learning and memory impairment in rats

scientific article

Signaling by carcinogenic metals and metal-induced reactive oxygen species

journal article published in 2003

Signaling from toxic metals to NF-kappaB and beyond: not just a matter of reactive oxygen species ⬇️

journal article published in 2002

Silica induces cell cycle changes through PI-3K/AP-1 pathway in human embryo lung fibroblast cells

journal article published in 2010

Silica radical-induced DNA damage and lipid peroxidation ⬇️

journal article published in 1994

Silica-induced pulmonary inflammation in rats: activation of NF Kappa B and its supression by dexamethasone ⬇️

abstract published in 1998

Single-walled carbon nanotubes: geno- and cyto-toxic effects in lung fibroblast V79 cells ⬇️

abstract published in 2008

Sodium fluoride induces apoptosis in mouse embryonic stem cells through ROS-dependent and caspase- and JNK-mediated pathways

scientific article published on 21 January 2012

Studies on three structurally related phenylenediamines with the mouse micronucleus assay system ⬇️

journal article published in 1991

Sulforaphane inhibited expression of hypoxia-inducible factor-1alpha in human tongue squamous cancer cells and prostate cancer cells

scientific article

Superoxide-independent reduction of vanadate by rat liver microsomes/NAD(P)H: Vanadate reductase activity ⬇️

scientific article published on May 15, 1992

Suppressed NF-kB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-a induced apoptosis in human cancer cells

journal article published in 2004

Sustained JNK1 activation is associated with altered histone H3 methylations in human liver cancer

journal article published in 2009

Synergistic antileukemic interactions between 2-medroxyestradiol (2-ME) and histone deacetylase inhibitors involve Akt down-regulation and oxidative stress

journal article published in 2006

Synthesis of Cr(IV)-GSH, its identification and its free hydroxyl radical generation: a model compound for Cr(VI) carcinogenicity

journal article published in 1997

Tetrandrine inhibits signal-induced NF-kB activation in rat alveolar macrophages

journal article published in 1997

The 9th Conference on Metal Toxicity and Carcinogenesis: The conference overview.

scientific article published on 12 April 2017

The Autophagy Receptor Adaptor p62 is Up-regulated by UVA Radiation in Melanocytes and in Melanoma Cells

scientific article

The dual roles of c-Jun NH2-terminal kinase signaling in Cr(VI)-induced apoptosis in JB6 cells

scientific article

The human mineral dust-induced gene, mdig, is a cell growth regulating gene associated with lung cancer

journal article published in 2005

The role of NF-kappaB in 1-->3-beta-glucan(zymosan)induced TNF-alpha production ⬇️

conference proceedings item published in 2000

The role of NFkB in (1-->3)-B-glucan (Zymosan A) induced TNF-alpha production

conference abstract published in 2000

The role of epidermal growth factor receptor in ethanol-mediated inhibition of activator protein-1 transactivation

scientific article

The role of hydroxyl radical as a messenger in Cr(VI)-induced p53 activation

journal article published in 2000

The role of hydroxyl radical as a messenger in the activation of nuclear transcription factor NFKB

journal article published in 1999

The role of phosphatidylinositol-3 kinase in vanadate-promoted S phase entry

journal article published in 2004

The role of superoxide radical in TNF-alpha induced NF-kappaB activation ⬇️

journal article published in 1999

Transactivation of RARE and GRE in the cellular response to arsenic

journal article published in 2001

Transplacental genotoxicity of triethylenemelamine, benzene, and vinblastine in mice

journal article published in 1992

Tungsten carbide-cobalt particles activate Nrf2 and its downstream target genes in JB6 cells possibly by ROS generation

journal article published in 2010

Tunicamycin-induced unfolded protein response in the developing mouse brain

scientific article

UV induces phosphorylation of protein kinase B (Akt) at Ser-473 and Thr-308 in mouse epidermal C1 41 cells through hydrogen peroxide ⬇️

journal article published in 2001

Ultraviolet-induced phosphorylation of p70(S6k) at Thr(389) and Thr(421)/Ser(424) involves hydrogen peroxide and mammalian target of rapamycin but not Akt and atypical protein kinase c ⬇️

journal article published in 2002

Upregulation of histone-lysine methyltransferases plays a causal role in hexavalent chromium-induced cancer stem cell-like property and cell transformation

scientific article published on 29 January 2018

Upstream Signal Transduction of NF-κB Activation ⬇️

scientific article published on June 1, 2002

Ursolic acid induces apoptosis in human leukaemia cells and exhibits anti‐leukaemic activity in nude mice through the PKB pathway ⬇️

scientific article published on March 1, 2012

Vanadate activated Akt and promoted S phase entry

journal article published in 2004

Vanadate induces G2/M phase arrest in p53-deficient mouse embryo fibroblasts ⬇️

journal article published in 2002

Vanadate induces apoptosis in epidermal JB6 P+ cells via hydrogen peroxide-mediated reactions

journal article published in 1999

Vanadate induces cell growth arrest through MAPKs and reactive oxygen species

conference abstract published in 2001

Vanadate induces p53 transactivation through hydrogen peroxide and causes apoptosis

journal article published in 2000

Vanadate induction of NF-kB involves IkB kinase B and SAPK/ERK kinasa 1 in macrophages ⬇️

journal article published in 1999

Vanadate-Induced Cell Growth Arrest is p53-dependent through Activation of p21 in C141 Cells

journal article published in 2002

Vanadate-induced cell growth regulation and the role of reactive oxygen species

journal article published in 2001

Vanadate-induced expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor through phosphatidylinositol 3-kinase/Akt pathway and reactive oxygen species ⬇️

journal article published in 2002

Vanadium (IV) formation in the reduction of vanadate by glutathione reductase/NADPH and the role of molecular oxygen ⬇️

scientific article published on November 1, 1997

Vanadium-induced apoptosis and pulmonary inflammation in mice: role of reactive oxygen species

journal article published in 2003

Vanadium-induced nuclear factor of activated T cells activation through hydrogen peroxide ⬇️

journal article published in 2001

Vanadium-induced pulmonary inflammation and apoptosis in mice ⬇️

abstract published in 2002

Withdrawal: Antioncogenic and oncogenic properties of Nrf2 in arsenic-induced carcinogenesis

scientific article published in Journal of Biological Chemistry

Withdrawal: Nrf2/p62 signaling in apoptosis resistance and its role in cadmium-induced carcinogenesis

scientific article published in Journal of Biological Chemistry

Withdrawal: Nuclear factor erythroid 2-related factor 2 enhances carcinogenesis by suppressing apoptosis and promoting autophagy in nickel-transformed cells

scientific article published in Journal of Biological Chemistry

Wood smoke particles generate free radicals and cause lipid peroxidation, DNA damage, NFkappaB activation and TNF-alpha release in macrophages

journal article published in 2000

[Role of telomerase in silica induced human cell transformation].

scientific article

miR-190-Mediated Downregulation of PHLPP Contributes to Arsenic-Induced Akt Activation and Carcinogenesis ⬇️

scientific article published on July 12, 2011

p27 suppresses arsenite-induced Hsp27/Hsp70 expression through inhibiting JNK2/c-Jun- and HSF-1-dependent pathways

scientific article

p62 as a therapeutic target for inhibition of autophagy in prostate cancer

scientific article

trans-3,4,5'-Trihydroxystibene inhibits hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in human ovarian cancer cells

scientific article published on August 2004

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