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List of works by Amalia Azzariti

4-Biphenyl and 2-naphthyl substituted 6,7-dimethoxytetrahydroisoquinoline derivatives as potent P-gp modulators

scientific article published on 2 February 2008

A new generation of MDR modulating agents with dual activity: P-gp inhibitor and iNOS inducer agents

scientific article published on 13 November 2010

Anti-EGFR monoclonal antibody in cancer treatment: in vitro and in vivo evidence

scientific article published on January 2011

Antitumor potential of conjugable valinomycins bearing hydroxyl sites: in vitro studies.

scientific article

Aurora B kinase inhibitor AZD1152: determinants of action and ability to enhance chemotherapeutics effectiveness in pancreatic and colon cancer.

scientific article

Aurora kinase B inhibition reduces the proliferation of metastatic melanoma cells and enhances the response to chemotherapy

scientific article

Biomarkers of chemotherapeutics efficacy and toxicity in colorectal cancer

scientific article published on 01 December 2011

Carcinogenesis of pancreatic adenocarcinoma: precursor lesions.

scientific article published on 30 September 2013

Characterization of sequence-dependent synergy between ZD1839 ("Iressa") and oxaliplatin.

scientific article published in August 2003

Circulating extracellular vesicles expressing PD1 and PD-L1 predict response and mediate resistance to checkpoint inhibitors immunotherapy in metastatic melanoma

scientific article published on 18 January 2022

Co‐expression of CD133+/CD44+ in human colon cancer and liver metastasis ⬇️

scientific article published on February 1, 2013

Cumulative effects of mutations in newly synthesised mitochondrial aspartate aminotransferase on uptake into mitochondria

scientific article published on 01 September 1995

Cyclohexylpiperazine derivative PB28, a sigma2 agonist and sigma1 antagonist receptor, inhibits cell growth, modulates P-glycoprotein, and synergizes with anthracyclines in breast cancer.

scientific article

Cytochrome c is released from mitochondria in a reactive oxygen species (ROS)-dependent fashion and can operate as a ROS scavenger and as a respiratory substrate in cerebellar neurons undergoing excitotoxic death

scientific journal article

EGFR and VEGFR as potential target for biological therapies in HCC cells.

scientific article published on 11 January 2008

EGFR tyrosine kinases inhibitors in cancer treatment: in vitro and in vivo evidence.

scientific article published on January 2011

Expression of proteins involved in DNA damage response in familial and sporadic breast cancer patients.

scientific article published on 6 August 2015

Extracellular ADP prevents neuronal apoptosis via activation of cell antioxidant enzymes and protection of mitochondrial ANT-1.

scientific article

High-Throughput Analysis of the Drug Mode of Action of PB28, MC18 and MC70, Three Cyclohexylpiperazine Derivative New Molecules

Hydroxy-Propil-β-Cyclodextrin Inclusion Complexes of two Biphenylnicotinamide Derivatives: Formulation and Anti-Proliferative Activity Evaluation in Pancreatic Cancer Cell Models

scientific article published on 07 September 2020

Interaction of the sigma(2) receptor ligand PB28 with the human nucleosome: computational and experimental probes of interaction with the H2A/H2B dimer

scientific article

Intracellular trafficking of MDR transporters and relevance of SNPs.

scientific article published on January 2009

Irradiation-induced angiosarcoma and anti-angiogenic therapy: a therapeutic hope?

scientific article published on 31 December 2013

Kinase activation profile associated with TGF-β-dependent migration of HCC cells: a preclinical study.

scientific article published on 16 September 2010

Laminin-5 offsets the efficacy of gefitinib ('Iressa') in hepatocellular carcinoma cells.

scientific article published on November 2004

Laminin-5 stimulates hepatocellular carcinoma growth through a different function of alpha6beta4 and alpha3beta1 integrins.

scientific article published on December 2007

MC70 potentiates doxorubicin efficacy in colon and breast cancer in vitro treatment

scientific article published on 5 September 2011

Metastatic melanoma cells with BRAF G469A mutation: nab-paclitaxel better than vemurafenib?

scientific article published on 13 June 2015

MicroRNA expression in BRAF-mutated and wild-type metastatic melanoma and its correlation with response duration to BRAF inhibitors

scientific article published in January 2015

MicroRNA in pancreatic adenocarcinoma: predictive/prognostic biomarkers or therapeutic targets?

scientific article (publication date: 15 September 2015)

Natural history of malignant bone disease in gastric cancer: final results of a multicenter bone metastasis survey

scientific article

New insight into the role of metabolic reprogramming in melanoma cells harboring BRAF mutations

scientific article published on 16 August 2016

New vascular disrupting agents in upper gastrointestinal malignancies.

scientific article published on January 2014

Optimize radiochemotherapy in pancreatic cancer: PARP inhibitors a new therapeutic opportunity ⬇️

scientific article published on October 29, 2012

Optimized granulocyte colony-stimulating factor prophylaxis in adult cancer patients: from biological principles to clinical guidelines.

scientific article published on 23 March 2012

PI3K class IB controls the cell cycle checkpoint promoting cell proliferation in hepatocellular carcinoma

scientific article published on 24 January 2012

Pharmacokinetic and Metabolism Determinants of Fluoropyrimidines and Oxaliplatin Activity in Treatment of Colorectal Patients ⬇️

scientific article published on December 1, 2011

Phosphatidylinositol 3-kinase in breast cancer: where from here?

scientific article published on October 2007

Potential predictive role of chemotherapy-induced changes of soluble CD40 ligand in untreated advanced pancreatic ductal adenocarcinoma

scientific article published on 28 July 2016

Predictive factors to targeted treatment in gastrointestinal carcinomas.

scientific article published on January 2014

Proteomic profile and in silico analysis in metastatic melanoma with and without BRAF mutation

scientific article

Sigma-2 receptor agonists as possible antitumor agents in resistant tumors: hints for collateral sensitivity

scientific article published on 19 September 2013

Small P-gp modulating molecules: SAR studies on tetrahydroisoquinoline derivatives

scientific article

Sporadic melanoma in South-Eastern Italy: the impact of melanocortin 1 receptor (MC1R) polymorphism analysis in low-risk people and report of three novel variants

scholarly article by Stefania Guida et al published August 2015 in Archives of Dermatological Research

Synthesis, Characterization, and Cytotoxicity of the First Oxaliplatin Pt(IV) Derivative Having a TSPO Ligand in the Axial Position.

scientific article published on 25 June 2016

Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activity

scientific article

Synthetic lethality to overcome cancer drug resistance.

scientific article published on January 2012

Target therapies in pancreatic carcinoma.

scientific article published on January 2014

Targeted therapies in upper gastrointestinal malignancies

scientific article published on 01 January 2014

Targeting human liver cancer cells with lactobionic acid-G(4)-PAMAM-FITC sorafenib loaded dendrimers.

scientific article

The Coordinated Role of CYP450 Enzymes and P-gp in Determining Cancer Resistance to Chemotherapy ⬇️

scientific article published on October 1, 2011

The EGFR pathway regulates BCRP expression in NSCLC cells: role of erlotinib

scientific article

The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells.

scientific article

The Role of Non-Coding RNAs as Prognostic Factor, Predictor of Drug Response or Resistance and Pharmacological Targets, in the Cutaneous Squamous Cell Carcinoma

scientific article published on 08 September 2020

The clinical development of inhibitors of poly(ADP-ribose) polymerase.

scientific article published on January 2011

The impact of folate status on the efficacy of colorectal cancer treatment.

scientific article published on December 2011

The interaction of celecoxib with MDR transporters enhances the activity of mitomycin C in a bladder cancer cell line

scientific article published on 24 May 2013

The next generation of metastatic melanoma: uncovering the genetic variants for anti-BRAF therapy response

scientific article

Total and not bevacizumab-bound vascular endothelial growth factor as potential predictive factors to bevacizumab-based chemotherapy in colorectal cancer

scientific article published on July 2016

Trimethoxybenzanilide-based P-glycoprotein modulators: an interesting case of lipophilicity tuning by intramolecular hydrogen bonding

scientific article

Update on capecitabine alone and in combination regimens in colorectal cancer patients

scientific article

Use of protease sensitivity to probe the conformations of newly synthesised mutant forms of mitochondrial aspartate aminotransferase

scientific article published on 01 October 1995

miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives

scientific article published on 30 April 2014

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