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List of works by Andrew J Roe

A Highly Conserved Bacterial D-Serine Uptake System Links Host Metabolism and Virulence

scientific article

A highly conserved complete accessory Escherichia coli type III secretion system 2 is widespread in bloodstream isolates of the ST69 lineage

scientific article published on 05 March 2020

A highly conserved complete accessoryEscherichia colitype III secretion system 2 is widespread in bloodstream isolates of the ST69 lineage

Aldehyde-alcohol dehydrogenase forms a high-order spirosome architecture critical for its activity

scientific article published on 04 October 2019

Aldehyde-alcohol dehydrogenase undergoes structural transition to form extended spirosomes for substrate channeling

scientific article published on 10 June 2020

Analysis of the expression, regulation and export of NleA-E in Escherichia coli O157 : H7.

scientific article published in May 2007

Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis

scientific article

Characterization of the Mode of Action of Aurodox, a Type III Secretion System Inhibitor from Streptomyces goldiniensis

scientific article published on 24 January 2019

Co-ordinate single-cell expression of LEE4- and LEE5-encoded proteins of Escherichia coli O157:H7.

scientific article published in October 2004

Control freaks-signals and cues governing the regulation of virulence in attaching and effacing pathogens.

scientific article

Cultured enterocytes internalise bacteria across their basolateral surface for, pathogen-inhibitable, trafficking to the apical compartment

scientific article published on 27 November 2015

Distinct intraspecies virulence mechanisms regulated by a conserved transcription factor

scientific article published on 09 September 2019

Diversity in the structures and ligand-binding sites of nematode fatty acid and retinol-binding proteins revealed by Na-FAR-1 from Necator americanus

scientific article

Enhancement of bacterial competitive fitness by apramycin resistance plasmids from non-pathogenic Escherichia coli.

scientific article published on September 2006

Escherichia coli O157 : H7 forms attaching and effacing lesions at the terminal rectum of cattle and colonization requires the LEE4 operon.

scientific article

Express your LOV: an engineered flavoprotein as a reporter for protein expression and purification.

scientific article

Expression and regulation of the Escherichia coli O157:H7 effector proteins NleH1 and NleH2

scientific article (publication date: 2012)

Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase from Yersinia pseudotuberculosis

scientific article published on 25 November 2010

FolX from Pseudomonas aeruginosa is octameric in both crystal and solution

scientific article

Genomic plasticity of pathogenic Escherichia coli mediates d-serine tolerance via multiple adaptive mechanisms

scientific article published on 26 August 2020

Glutathione is involved in environmental stress responses in Rhizobium tropici, including acid tolerance.

scientific article

Heterogeneity in populations of enterohaemorrhagic Escherichia coli undergoing D-serine adaptation

scientific article published on 21 November 2020

Heterogeneous Surface Expression of EspA Translocon Filaments by Escherichia coli O157:H7 Is Controlled at the Posttranscriptional Level

scientific article published on October 1, 2003

Hierarchal type III secretion of translocators and effectors from Escherichia coli O157:H7 requires the carboxy terminus of SepL that binds to Tir.

scientific article published on 30 July 2008

High-throughput identification of purification conditions leads to preliminary crystallization conditions for three inner membrane proteins.

scientific article

Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion

scientific article published in Nature Communications

Identification and Characterization of Novel Compounds Blocking Shiga Toxin Expression in Escherichia coli O157:H7.

scientific article

Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence-blocking compounds.

scientific article published on July 2011

Increased adherence and actin pedestal formation by dam-deficient enterohaemorrhagic Escherichia coli O157:H7.

scientific article published in March 2007

Inhibition of Escherichia coli growth by acetic acid: a problem with methionine biosynthesis and homocysteine toxicity.

scientific article published on July 2002

Intracellular d-Serine Accumulation Promotes Genetic Diversity via Modulated Induction of RecA in Enterohemorrhagic Escherichia coli.

scientific article published on 3 October 2016

Lighting Up Clostridium Difficile: Reporting Gene Expression Using Fluorescent Lov Domains.

scientific article

Lysogeny with Shiga toxin 2-encoding bacteriophages represses type III secretion in enterohemorrhagic Escherichia coli.

scientific article

Mutation of toxB and a truncated version of the efa-1 gene in Escherichia coli O157:H7 influences the expression and secretion of locus of enterocyte effacement-encoded proteins but not intestinal colonization in calves or sheep.

scientific article published on September 2004

Novel compounds targeting the enterohemorrhagic Escherichia coli type three secretion system reveal insights into mechanisms of secretion inhibition

scientific article published on 29 May 2017

Perturbation of Anion Balance during Inhibition of Growth of Escherichia coli by Weak Acids

scientific article published on February 1, 1998

Postgenomics Characterization of an Essential Genetic Determinant of Mammary Pathogenic Escherichia coli.

scientific article published on 3 April 2018

Rapid inactivation of the Escherichia coli Kdp K+ uptake system by high potassium concentrations

scientific article published on 01 March 2000

Salmonella Transforms Follicle-Associated Epithelial Cells into M Cells to Promote Intestinal Invasion

scientific article (publication date: November 2012)

Structural Characterisation of Tpx from Yersinia pseudotuberculosis Reveals Insights into the Binding of Salicylidene Acylhydrazide Compounds

scientific article

Structure and ligand binding of As-p18, an extracellular fatty acid binding protein from the eggs of a parasitic nematode

scientific article published on 23 July 2019

The host metabolite D-serine contributes to bacterial niche specificity through gene selection.

scientific article

The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7

scientific article

Tracking elusive cargo: Illuminating spatio-temporal Type 3 effector protein dynamics using reporters.

scientific article published on 31 October 2017

Transcriptional regulators of the GAD acid stress island are carried by effector protein-encoding prophages and indirectly control type III secretion in enterohemorrhagic Escherichia coli O157:H7

article

Two crystal forms of a helix-rich fatty acid- and retinol-binding protein, Na-FAR-1, from the parasitic nematode Necator americanus

scientific article

Use of a dual reporter plasmid to demonstrate Bactofection with an attenuated AroA(-) derivative of Pasteurella multocida B:2

scientific article

Useable diffraction data from a multiple microdomain-containing crystal of Ascaris suum As-p18 fatty-acid-binding protein using a microfocus beamline

scientific article

Visualizing the Translocation and Localization of Bacterial Type III Effector Proteins by Using a Genetically Encoded Reporter System

scientific article

Widespread Strain-Specific Distinctions in Chromosomal Binding Dynamics of a Highly Conserved Escherichia coli Transcription Factor

scientific article published on 23 June 2020

d-Serine induces distinct transcriptomes in diverse Escherichia coli pathotypes

scientific article published in 2021