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List of works by Giorgia Simonetti

5'UTR point substitutions and N-terminal truncating mutations of ANKRD26 in acute myeloid leukemia

scientific article published on 18 January 2017

A WEE1 family business: regulation of mitosis, cancer progression, and therapeutic target

scientific article published on 21 September 2020

A novel Rag2-/-gammac-/--xenograft model of human CLL.

scientific article

Aneuploidy: Cancer strength or vulnerability?

scientific article published on 31 October 2018

Axitinib in Ponatinib-Resistant B-Cell Acute Lymphoblastic Leukemia Harboring a T315L Mutation

scientific article published on 20 December 2020

Chromothripsis in acute myeloid leukemia: biological features and impact on survival

scientific article published on 23 February 2018

Chronic myeloid leukemia stem cells

scientific article published on 24 May 2019

Efficacy of Azacitidine in the treatment of adult patients aged 65 years or older with AML.

scientific article published on 10 November 2016

Epigenetically induced ectopic expression of UNCX impairs the proliferation and differentiation of myeloid cells

scientific article

Fanconi anemia gene variants in therapy-related myeloid neoplasms.

scientific article published on 3 July 2015

Germinal center B cell maintenance and differentiation are controlled by distinct NF-κB transcription factor subunits

scientific article

HS1 has a central role in the trafficking and homing of leukemic B cells

scientific article

IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity.

scientific article published on 09 December 2013

Identification of Two DNMT3A Mutations Compromising Protein Stability and Methylation Capacity in Acute Myeloid Leukemia

scientific article published on 30 October 2019

Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models.

scientific article published on 7 June 2011

Loss of PALB2 predicts poor prognosis in acute myeloid leukemia and suggests novel therapeutic strategies targeting the DNA repair pathway

scientific article published on 07 January 2021

Mouse models in the study of chronic lymphocytic leukemia pathogenesis and therapy

scientific article published on 8 July 2014

Network integration of multi-tumour omics data suggests novel targeting strategies

scientific article published in Nature Communications

Optimized pipeline of MuTect and GATK tools to improve the detection of somatic single nucleotide polymorphisms in whole-exome sequencing data

scientific article

Revealing very small FLT3 ITD mutated clones by ultra-deep sequencing analysis has important clinical implications in AML patients

scientific article published on 5 September 2015

SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders

scientific article published on 23 May 2014

Synergism Through WEE1 and CHK1 Inhibition in Acute Lymphoblastic Leukemia

scientific article published on 25 October 2019

Targeting Macrophages Sensitizes Chronic Lymphocytic Leukemia to Apoptosis and Inhibits Disease Progression

scientific article published on 10 February 2016

Targeting the p53-MDM2 interaction by the small-molecule MDM2 antagonist Nutlin-3a: a new challenged target therapy in adult Philadelphia positive acute lymphoblastic leukemia patients

scientific article published on 12 February 2016

The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia

scientific article published on 6 December 2017

The diverse roles of IRF4 in late germinal center B‐cell differentiation

scientific article published on May 1, 2012

The human Smoothened inhibitor PF-04449913 induces exit from quiescence and loss of multipotent Drosophila hematopoietic progenitor cells

scientific article published on 28 July 2016

The role of toll-like receptors in chronic B-cell malignancies

scientific article published on October 2009

Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4

scientific article published on 16 May 2013