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List of works by Loris De Cecco

A functional gene expression analysis in epithelial sinonasal cancer: Biology and clinical relevance behind three histological subtypes

article

A novel crosstalk between CCAR2 and AKT pathway in the regulation of cancer cell proliferation

scientific article

Activity and safety of afatinib in a window pre-operative EORTC study in patients with squamous cell carcinoma of the head and neck (SCCHN).

scientific article published on 15 January 2018

Adaptive Immunity in Fibrosarcomatous Dermatofibrosarcoma Protuberans and Response to Imatinib Treatment.

scientific article published on 5 September 2016

Age-Related Alterations in Immune Contexture Are Associated with Aggressiveness in Rhabdomyosarcoma

scientific article published on 17 September 2019

Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer.

scientific article published in September 2004

Analysis of gene expression identifies PLAB as a mediator of the apoptotic activity of fenretinide in human ovarian cancer cells.

scientific article published on 8 January 2007

Are Fusion Transcripts in Relapsed/Metastatic Head and Neck Cancer Patients Predictive of Response to Anti-EGFR Therapies?

scientific article published on 12 November 2017

Association of lung adenocarcinoma clinical stage with gene expression pattern in noninvolved lung tissue

article

Augmentation of response to chemotherapy by microRNA-506 through regulation of RAD51 in serous ovarian cancers

scientific article

CDCP1 is a novel marker of the most aggressive human triple-negative breast cancers

scientific article published on 10 September 2016

CTAB-urea method purifies RNA from melanin for cDNA microarray analysis

scientific article

Challenges in projecting clustering results across gene expression-profiling datasets

scientific article

Choline kinase-alpha by regulating cell aggressiveness and drug sensitivity is a potential druggable target for ovarian cancer.

scientific article

Circulating miR-375 as a novel prognostic marker for metastatic medullary thyroid cancer patients

scientific article published on 3 January 2018

Comparison of microarray platforms for measuring differential microRNA expression in paired normal/cancer colon tissues.

scientific article

Complex genetic control of lung tumorigenesis in resistant mice strains.

scientific article published on 10 August 2017

Comprehensive gene expression meta-analysis of head and neck squamous cell carcinoma microarray data defines a robust survival predictor.

scientific article

Cost-effectiveness of Molecular Profile Patient Selection for First-line Treatment of Recurrent/Metastatic Head and Neck Cancer

scientific article published on 17 October 2019

Development and validation of a microRNA-based signature (MiROvaR) to predict early relapse or progression of epithelial ovarian cancer: a cohort study.

scientific article published on 8 July 2016

Effects of warm ischemic time on gene expression profiling in colorectal cancer tissues and normal mucosa

scientific article

Expression and prognostic significance of the autoimmune regulator gene in breast cancer cells

scientific article published on 18 October 2016

Expression quantitative trait analysis reveals fine germline transcript regulation in mouse lung tumors

scientific article published on 7 March 2016

Extracellular Matrix Features Discriminate Aggressive HER2-Positive Breast Cancer Patients Who Benefit from Trastuzumab Treatment

scientific article published on 13 February 2020

FGFR4 Gly388Arg polymorphism may affect the clinical stage of patients with lung cancer by modulating the transcriptional profile of normal lung.

scientific article published in June 2009

Feasibility of circulating miRNA microarray analysis from archival plasma samples

scientific article published on 13 March 2013

Focal Recurrent Copy Number Alterations Characterize Disease Relapse in High Grade Serous Ovarian Cancer Patients with Good Clinical Prognosis: A Pilot Study

scientific article published on 05 September 2019

Functional Genomics Uncover the Biology behind the Responsiveness of Head and Neck Squamous Cell Cancer Patients to Cetuximab.

scientific article

Gene Expression Clustering and Selected Head and Neck Cancer Gene Signatures Highlight Risk Probability Differences in Oral Premalignant Lesions

scientific article published on 03 August 2020

Gene Expression Signatures for Head and Neck Cancer Patient Stratification: Are Results Ready for Clinical Application?

scientific article

Gene expression analysis reveals a different transcriptomic landscape in female and male breast cancer.

scientific article published on 13 July 2010

Gene expression profile identifies a rare epithelioid variant case of pleomorphic liposarcoma carrying FUS-CHOP transcript.

scientific article

Gene expression profiling integrated into network modelling reveals heterogeneity in the mechanisms of BRCA1 tumorigenesis

scientific article published on October 2009

Gene expression profiling of advanced ovarian cancer: characterization of a molecular signature involving fibroblast growth factor 2.

scientific article published on October 2004

Gene expression signature of non-involved lung tissue associated with survival in lung adenocarcinoma patients.

scientific article published on 25 August 2013

Gene signatures and expression of miRNAs associated with efficacy of panitumumab in a head and neck cancer phase II trial

scientific article published on 28 May 2018

Genomic Landscape of Ovarian Cancer

Head and neck cancer subtypes with biological and clinical relevance: Meta-analysis of gene-expression data

scientific article

Heterogeneous expression of the collagen receptor DDR1 in chronic lymphocytic leukaemia and correlation with progression.

scientific article published on 06 January 2017

Increased sensitivity to chemotherapy induced by CpG-ODN treatment is mediated by microRNA modulation

scientific article

Induction of Paneth cell degranulation by orally administered Toll-like receptor ligands

scientific article published on 01 March 2012

Integrated transcriptional-phenotypic analysis captures systemic immunomodulation following antiangiogenic therapy in renal cell carcinoma patients

scientific article published on 01 June 2021

Integrative miRNA-Gene Expression Analysis Enables Refinement of Associated Biology and Prediction of Response to Cetuximab in Head and Neck Squamous Cell Cancer.

scientific article published on 14 January 2017

Interleukin 21 Controls mRNA and MicroRNA Expression in CD40-Activated Chronic Lymphocytic Leukemia Cells

scientific article published on 25 August 2015

Limits of predictive models using microarray data for breast cancer clinical treatment outcome

scientific article

Measuring microRNA expression levels in oncology: from samples to data analysis.

scientific article

MicroRNA detection in plasma samples: how to treat heparinized plasma

scientific article published in January 2013

MicroRNA signature of malignant mesothelioma with potential diagnostic and prognostic implications

scientific article published on 05 June 2009

Mining of Self-Organizing Map Gene-Expression Portraits Reveals Prognostic Stratification of HPV-Positive Head and Neck Squamous Cell Carcinoma

scientific article published on 26 July 2019

Modulation of DNA repair genes induced by TLR9 agonists: A strategy to eliminate "altered" cells?

scientific article published on March 2012

Molecular portrait of breast cancer in China reveals comprehensive transcriptomic likeness to Caucasian breast cancer and low prevalence of luminal A subtype.

scientific article published on 18 March 2015

Mouse pulmonary adenoma susceptibility 1 locus is an expression QTL modulating Kras-4A

scientific article (publication date: April 2014)

N(6)-isopentenyladenosine and analogs activate the NRF2-mediated antioxidant response

scientific article

New transcriptional-based insights into the pathogenesis of desmoplastic small round cell tumors (DSRCTs)

scientific article published on 22 March 2017

Ovarian Cancer Translational Activity of the Multicenter Italian Trial in Ovarian Cancer (MITO) Group: Lessons Learned in 10 Years of Experience

scientific article published on 07 April 2020

Overcoming melanoma resistance to vemurafenib by targeting CCL2-induced miR-34a, miR-100 and miR-125b

scientific article published on 14 December 2015

PKC-alpha modulation by miR-483-3p in platinum-resistant ovarian carcinoma cells

scientific article published on 20 August 2016

Patterns and changes in gene expression following neo-adjuvant anti-estrogen treatment in estrogen receptor-positive breast cancer

scientific article

Perfusion of isolated rat kidney with Mesenchymal Stromal Cells/Extracellular Vesicles prevents ischaemic injury.

scientific article published on 21 June 2017

Results of nimotuzumab and vinorelbine, radiation and re-irradiation for diffuse pontine glioma in childhood.

scientific article published on 3 April 2014

Retina-derived POU domain factor 1 coordinates expression of genes relevant to renal and neuronal development

scientific article published on 14 July 2016

Role of microRNAs in ovarian cancer pathogenesis and potential clinical implications

scientific article published on 24 December 2009

SOCS2 Controls Proliferation and Stemness of Hematopoietic Cells under Stress Conditions and Its Deregulation Marks Unfavorable Acute Leukemias

scientific article published on 9 April 2015

Specific gene expression profiles distinguish among functional allelic variants of the mouse Pthlh gene in transfected human cancer cells.

scientific article published on 20 March 2006

TLR9 agonists oppositely modulate DNA repair genes in tumor versus immune cells and enhance chemotherapy effects.

scientific article

The genomics of desmoplastic small round cell tumor reveals the deregulation of genes related to DNA damage response, epithelial-mesenchymal transition, and immune response

article

The molecular and gene/miRNA expression profiles of radioiodine resistant papillary thyroid cancer

scientific article published on 16 November 2020

Transcriptional characteristics of familial non-BRCA1/BRCA2 breast tumors.

scientific article

Transcriptional profiling of melanoma sentinel nodes identify patients with poor outcome and reveal an association of CD30(+) T lymphocytes with progression

scientific article published on January 2014

Tumor Biomarkers for the Prediction of Distant Metastasis in Head and Neck Squamous Cell Carcinoma

scientific article published on 09 April 2020

Whole exome sequencing and single nucleotide polymorphism array analyses to identify germline alterations in genes associated with testosterone metabolism in a patient with androgen insensitivity syndrome and early-onset colorectal cancer

scientific article published on 07 June 2016

Whole-transcriptome analysis links trastuzumab sensitivity of breast tumors to both HER2 dependence and immune cell infiltration

scientific article

miR-342 regulates BRCA1 expression through modulation of ID4 in breast cancer

scientific article published on 27 January 2014

miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma.

scientific article published on 08 February 2016

miRNA control of apoptotic programs: focus on ovarian cancer

scientific article published on April 2011

β-Catenin in desmoid-type fibromatosis: deep insights into the role of T41A and S45F mutations on protein structure and gene expression.

scientific article published on 19 June 2017