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List of works by Detlef H Heck

A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer's mouse model via an HSF1-mediated mechanism.

scientific article published on 26 July 2016

A low-cost solution to measure mouse licking in an electrophysiological setup with a standard analog-to-digital converter.

scientific article published on 20 December 2005

Abnormalities in Dynamic Brain Activity Caused by Mild Traumatic Brain Injury Are Partially Rescued by the Cannabinoid Type-2 Receptor Inverse Agonist SMM-189.

scientific article published on July 2017

Analysis of cerebellar function in Ube3a-deficient mice reveals novel genotype-specific behaviors

scientific article

Background firing rate affects the signal transfer of behavior locked input patterns from Purkinje cells to the cerebellar nuclei.

scientific article published on 16 July 2012

Behavior-Related Pauses in Simple-Spike Activity of Mouse Purkinje Cells Are Linked to Spike Rate Modulation ⬇️

scientific article published on June 20, 2012

Behavioral flexibility in a mouse model of developmental cerebellar Purkinje cell loss

scientific article

Born to Cry: A Genetic Dissection of Infant Vocalization

scientific article published on 29 October 2018

Breathing as a Fundamental Rhythm of Brain Function

scientific article

C57BL/6J and DBA/2J mice vary in lick rate and ingestive microstructure.

scientific article published on 21 December 2006

Causal Evidence for a Role of Cerebellar Lobulus Simplex in Prefrontal-Hippocampal Interaction in Spatial Working Memory Decision-Making

scientific article published in 2022

Cerebellar Lobulus Simplex and Crus I Differentially Represent Phase and Phase Difference of Prefrontal Cortical and Hippocampal Oscillations

scientific article published on 01 May 2019

Cerebellar Purkinje Cells Generate Highly Correlated Spontaneous Slow-Rate Fluctuations

scientific article published on 20 September 2017

Cerebellar cortical output encodes temporal aspects of rhythmic licking movements and is necessary for normal licking frequency.

scientific article published on 28 June 2010

Cerebellar modulation of frontal cortex dopamine efflux in mice: relevance to autism and schizophrenia

scientific article published on July 2008

Cerebellar structure and function: making sense of parallel fibers.

scientific article published in September 2002

Cerebellar zonal patterning relies on Purkinje cell neurotransmission.

scientific article

Comprehensive analysis of ultrasonic vocalizations in a mouse model of fragile X syndrome reveals limited, call type specific deficits

scientific article

Comprehensive motor testing in Fmr1-KO mice exposes temporal defects in oromotor coordination

scientific article published on 17 October 2011

Connecting the dots of the cerebro-cerebellar role in cognitive function: neuronal pathways for cerebellar modulation of dopamine release in the prefrontal cortex.

scientific article published on 17 June 2011

Consensus Paper: Experimental Neurostimulation of the Cerebellum

scientific article published on 01 December 2019

Consensus paper: pathological role of the cerebellum in autism

scientific article

Controlling synaptic input patterns in vitro by dynamic photo stimulation

scientific article published on 31 May 2005

Dab2IP GTPase activating protein regulates dendrite development and synapse number in cerebellum

scientific article

Detection of sequences in the cerebellar cortex: numerical estimate of the possible number of tidal-wave inducing sequences represented.

scientific article published in July 2003

Dynamic correlation between whisking and breathing rhythms in mice.

scientific article

Dynamic correlation of neuronal activity in rat cerebellar cortex modulated by behavior.

scientific article published in December 2002

Emerging connections between cerebellar development, behaviour and complex brain disorders

scientific article published on 01 May 2019

Gamma band LFP in mouse barrel cortex is coupled to respiratory rhythm.

scientific article

Genetic control of a central pattern generator: rhythmic oromotor movement in mice is controlled by a major locus near Atp1a2.

scientific article

Hippocampal sharp-wave ripples in awake mice are entrained by respiration.

scientific article published on 21 August 2017

Histopathological and postoperative behavioral comparison of rodent oral tongue resection: fiber-enabled CO2 laser versus electrocautery

scientific article

Hsp90 inhibitor induces nuclear translocation of HSF1 predominantly in hippocampal CA1 region.

scientific article published in July 2017

Investigating dynamic aspects of brain function in slice preparations: spatiotemporal stimulus patterns generated with an easy-to-build multi-electrode array

scientific article published on 01 May 1995

Lentiviral-mediated knock-down of GD3 synthase protects against MPTP-induced motor deficits and neurodegeneration

scientific article published on 01 November 2018

Loss of cerebellar function selectively affects intrinsic rhythmicity of eupneic breathing

scientific article published on 21 February 2020

Medial cerebellar nuclear projections and activity patterns link cerebellar output to orofacial and respiratory behavior.

scientific article published on 2 April 2013

Minimally invasive highly precise monitoring of respiratory rhythm in the mouse using an epithelial temperature probe.

scientific article published on 8 February 2016

Normal social seeking behavior, hypoactivity and reduced exploratory range in a mouse model of Angelman syndrome

scientific article

Opposing phenotypes in mice with Smith-Magenis deletion and Potocki-Lupski duplication syndromes suggest gene dosage effects on fluid consumption behavior.

scientific article

Parallel Optical Control of Spatiotemporal Neuronal Spike Activity Using High-Speed Digital Light Processing ⬇️

scientific article published on August 25, 2011

Passive spatial and temporal integration of excitatory synaptic inputs in cerebellar Purkinje cells of young rats.

scientific article published in April 2003

Prenatal alcohol exposure delays acquisition and use of skilled reaching movements in juvenile rats.

scientific article published on 31 March 2008

Recent advances in understanding the mechanisms of cerebellar granule cell development and function and their contribution to behavior.

scientific article

Reorganization of circuits underlying cerebellar modulation of prefrontal cortical dopamine in mouse models of autism spectrum disorder

scientific article published on August 2013

Respiratory rhythms of the predictive mind.

scientific article published in 2022

Rhythms of the body, rhythms of the brain: Respiration, neural oscillations, and embodied cognition

scientific article published on 23 October 2017

Robust transmission of rate coding in the inhibitory Purkinje cell to cerebellar nuclei pathway in awake mice

scientific article

Sequential stimulation of guinea pig cerebellar cortex in vitro strongly affects Purkinje cells via parallel fibers

scientific article published on 01 April 1995

Sequential stimulation of rat and guinea pig cerebellar granular cells in vitro leads to increasing population activity in parallel fibers.

scientific article

Shaping Diversity Into the Brain's Form and Function

scientific article published on 10 October 2018

Single-unit analysis of substantia nigra pars reticulata neurons in freely behaving rats with genetic absence epilepsy.

scientific article

Stereotypical spatiotemporal activity patterns during slow-wave activity in the neocortex.

scientific article published on 17 August 2011

Synaptic integration in rat frontal cortex shaped by network activity.

scientific article

Thalamocortical Communication in the Awake Mouse Visual System Involves Phase Synchronization and Rhythmic Spike Synchrony at High Gamma Frequencies

scientific article published on 22 November 2018

The Age of Enlightenment: Evolving Opportunities in Brain Research Through Optical Manipulation of Neuronal Activity ⬇️

scientific article published on 07 December 2011

The Roles of the Olivocerebellar Pathway in Motor Learning and Motor Control. A Consensus Paper.

scientific article published on 19 May 2016

The Social Life of Neurons: Synaptic Communication Deficits as a Common Denominator of Autism, Schizophrenia, and Other Cognitive Disorders ⬇️

scientific article published on August 1, 2012

The detection and generation of sequences as a key to cerebellar function: experiments and theory.

scientific article

The neuronal code(s) of the cerebellum

scientific article

The rhythm of memory: how breathing shapes memory function

scientific article published on 19 June 2019

Two-dimensional monitoring of spiking networks in acute brain slices

scientific article published in January 2002

Use of Granger causality analysis and artificial spike trains to examine pause coding in Purkinje cell spike activity related to rhythmic licking

scientific article

Voltage signals of individual Purkinje cell dendrites in rat cerebellar slices.

scientific article published in November 1997

Whisker barrel cortex delta oscillations and gamma power in the awake mouse are linked to respiration.

scientific article published on April 2014

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