List of works - Ignazio Caruana

3D modeling of human cancer: A PEG-fibrin hydrogel system to study the role of tumor microenvironment and recapitulate the in vivo effect of oncolytic adenovirus

scientific article published on 20 January 2016

AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis

scientific article published on 01 December 2018

Adoptive immunotherapy using PRAME-specific T cells in medulloblastoma

scientific article published on 03 April 2018

Armed oncolytic virus enhances immune functions of chimeric antigen receptor-modified T cells in solid tumors

scientific article

Bevacizumab-mediated tumor vasculature remodelling improves tumor infiltration and antitumor efficacy of GD2-CAR T cells in a human neuroblastoma preclinical model

scientific article published on 4 October 2017

Choice of costimulatory domains and of cytokines determines CAR T-cell activity in neuroblastoma.

scientific article published on 15 March 2018

Correction: JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction

scientific article published on 20 July 2020

Generation of multi-leukemia antigen-specific T cells to enhance the graft-versus-leukemia effect after allogeneic stem cell transplant

scientific article

Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes.

scientific article published on 13 April 2015

Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma

scientific article published on 08 January 2021

JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction

scientific article published on 28 April 2020

K562-Derived Whole-Cell Vaccine Enhances Antitumor Responses of CAR-Redirected Virus-Specific Cytotoxic T Lymphocytes In Vivo

scientific article published on 17 February 2015

MB-64ADOPTIVE CELL IMMUNOTHERAPY IN MEDULLOBLASTOMA BASED ON T CELLS REDIRECTED TOWARD TUMOR CELLS BY PRAME SPECIFIC αβTCR GENE MODIFICATION.

scientific article published on 30 May 2016

Manipulating the Metabolism to Improve the Efficacy of CAR T-Cell Immunotherapy

scientific article published on 24 December 2020

Overcoming Challenges in CAR T-cell Product CGMP Release.

scientific article published on May 2016

Preservation of Antigen-Specific Functions of αβ T Cells and B Cells Removed from Hematopoietic Stem Cell Transplants Suggests Their Use As an Alternative Cell Source for Advanced Manipulation and Adoptive Immunotherapy

scientific article published on 23 March 2017

Reversible induction of mitophagy by an optogenetic bimodular system

scientific article published on 04 April 2019

Role of interferon-γ in immune-mediated graft failure after allogeneic hematopoietic stem cell transplantation

scientific article published on 21 February 2019

T lymphocytes redirected against the chondroitin sulfate proteoglycan-4 control the growth of multiple solid tumors both in vitro and in vivo.

scientific article published on 13 December 2013

TFG binds LC3C to regulate ULK1 localization and autophagosome formation

scientific article published on 01 May 2021

Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling

scientific article published on 24 July 2021

List of works by Ignazio Caruana