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List of works by Laura E Pascal

5α-Reductase inhibition coupled with short off cycles increases survival in the LNCaP xenograft prostate tumor model on intermittent androgen deprivation therapy.

scientific article

A Novel Small Molecule Targets Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer

scientific article published on 25 September 2019

A novel androgen receptor antagonist JJ-450 inhibits enzalutamide-resistant mutant ARF876L nuclear import and function

scientific article published on 23 December 2019

Activation of MAP kinases by hexavalent chromium, manganese and nickel in human lung epithelial cells

journal article published in 2006

Androgen receptor gene mutation, rearrangement, polymorphism.

scientific article published on September 2013

Combined Loss of EAF2 and p53 Induces Prostate Carcinogenesis in Male Mice.

scientific article

Conditional deletion of ELL2 induces murine prostate intraepithelial neoplasia

scientific article published in November 2017

Correlation of mRNA and protein levels: cell type-specific gene expression of cluster designation antigens in the prostate

scientific article

Cytotoxicity of chromium and manganese to lung epithelial cells in vitro

journal article published in 2004

DHX15 is up-regulated in castration-resistant prostate cancer and required for androgen receptor sensitivity to low DHT concentrations

scientific article published on 03 February 2019

DHX15 promotes prostate cancer progression by stimulating Siah2-mediated ubiquitination of androgen receptor.

scientific article

Development of a reactive stroma associated with prostatic intraepithelial neoplasia in EAF2 deficient mice

scientific article

Development of the Minimum Information Specification for In Situ Hybridization and Immunohistochemistry Experiments (MISFISHIE).

scientific article published on January 2006

Differential Inductive Signaling of CD90 Prostate Cancer-Associated Fibroblasts Compared to Normal Tissue Stromal Mesenchyme Cells.

scientific article published on 7 January 2011

Differential impact of paired patient-derived BPH and normal adjacent stromal cells on benign prostatic epithelial cell growth in 3D culture

scientific article published on 13 July 2020

E-cadherin is downregulated in benign prostatic hyperplasia and required for tight junction formation and permeability barrier in the prostatic epithelial cell monolayer

scientific article published on 18 June 2019

EAF2 and p53 Co-Regulate STAT3 Activation in Prostate Cancer.

scientific article published on 5 March 2018

EAF2 regulates DNA repair through Ku70/Ku80 in the prostate.

scientific article published on 10 October 2016

ELL2 Is Required for the Growth and Survival of AR-Negative Prostate Cancer Cells

scientific article published on 10 June 2020

ELL2 regulates DNA non-homologous end joining (NHEJ) repair in prostate cancer cells.

scientific article published on 24 November 2017

Embryonal carcinoma cell induction of miRNA and mRNA changes in co-cultured prostate stromal fibromuscular cells

scientific article published on June 2011

Gene Expression Profiling Reveals Regulation of ERK Phosphorylation by Androgen-Induced Tumor Suppressor U19/EAF2 in the Mouse Prostate.

scientific article published on 26 February 2013

Gene expression down-regulation in CD90+ prostate tumor-associated stromal cells involves potential organ-specific genes

scientific article published on 8 September 2009

Gene expression relationship between prostate cancer cells of Gleason 3, 4 and normal epithelial cells as revealed by cell type-specific transcriptomes ⬇️

scientific article

Hsp70 binds to the androgen receptor N-terminal domain and modulates the receptor function in prostate cancer cells

scientific article published on 08 October 2018

Improving intermittent androgen deprivation therapy: lessons learned from basic and translational research

scientific article

Inhibition of Androgen Receptor Function and Level in Castration-Resistant Prostate Cancer Cells by 2-[(isoxazol-4-ylmethyl)thio]-1-(4-phenylpiperazin-1-yl)ethanone.

scientific article published in October 2017

Inhibition of Androgen Receptor Nuclear Localization and Castration-Resistant Prostate Tumor Growth by Pyrroloimidazole-based Small Molecules.

scientific article published on 27 June 2017

Lineage relationship of prostate cancer cell types based on gene expression ⬇️

scientific article

Minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE)

scientific article

Molecular and cellular characterization of ABCG2 in the prostate

scientific article

Physical and Functional Interactions between ELL2 and RB in the Suppression of Prostate Cancer Cell Proliferation, Migration, and Invasion.

scientific article

Proteomic analysis of patient tissue reveals PSA protein in the stroma of benign prostatic hyperplasia.

scientific article

Regenerated luminal epithelial cells are derived from preexisting luminal epithelial cells in adult mouse prostate

scientific article

Regulation and targeting of androgen receptor nuclear localization in castration-resistant prostate cancer

scientific article published on 17 December 2020

Regulation of ELL2 stability and polyubiquitination by EAF2 in prostate cancer cells

scientific article published on 15 July 2018

SIRPB1 promotes prostate cancer cell proliferation via Akt activation

scientific article published on 06 January 2020

Stromal mesenchyme cell genes of the human prostate and bladder

scientific article

Stromal-epithelial interactions in early neoplasia

scientific article published on 01 January 2010

The N-terminal domain of the androgen receptor drives its nuclear localization in castration-resistant prostate cancer cells

scientific article

The urologic epithelial stem cell database (UESC) - a web tool for cell type-specific gene expression and immunohistochemistry images of the prostate and bladder

scientific article

Tight junction protein claudin-1 is downregulated by TGF-β1 via MEK signaling in benign prostatic epithelial cells

scientific article published on 21 July 2020

Two paths for stabilization of ERG in prostate carcinogenesis: TMPRSS2-ERG fusions and speckle-type pox virus and zinc finger protein mutations

scientific article published on 8 January 2016

Unzipping androgen action through ZIP9: a novel membrane androgen receptor.

scientific article

Virtual drug design: Skp1-Skp2 inhibition targets cancer stem cells

scientific article published on 30 September 2013

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