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List of works by Sergio Marchini

A prognostic regulatory pathway in stage I epithelial ovarian cancer: new hints for the poor prognosis assessment.

scientific article

A specific miRNA signature correlates with complete pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer.

scientific article

A systems biology approach to characterize the regulatory networks leading to trabectedin resistance in an in vitro model of myxoid liposarcoma

scientific article

A systems biology approach to investigate the mechanism of action of trabectedin in a model of myelomonocytic leukemia

scientific article published on 13 December 2016

Absence of deletions but frequent loss of expression of p16INK4 in human ovarian tumours ⬇️

scientific article published on January 1, 1997

Alpha-bromoacryloyl derivative of distamycin A (PNU 151807): a new non-covalent minor groove DNA binder with antineoplastic activity.

scientific article published on June 1999

Analysis of differential miRNA expression in primary tumor and stroma of colorectal cancer patients.

scientific article

Analysis of gene expression in early-stage ovarian cancer.

scientific article

Antiangiogenic activity of trabectedin in myxoid liposarcoma: Involvement of host TIMP-1 and TIMP-2 and tumor thrombospondin-1

scientific article published on 19 June 2014

Antitumour activity of trabectedin in myelodysplastic/myeloproliferative neoplasms.

scientific article published on 10 January 2017

Aplidine, a new anticancer agent of marine origin, inhibits vascular endothelial growth factor (VEGF) secretion and blocks VEGF-VEGFR-1 (flt-1) autocrine loop in human leukemia cells MOLT-4.

scientific article published on January 2003

Application of RNA-Seq transcriptome analysis: CD151 is an Invasion/Migration target in all stages of epithelial ovarian cancer

scientific article published on 24 January 2012

Association between miR-200c and the survival of patients with stage I epithelial ovarian cancer: a retrospective study of two independent tumour tissue collections.

scientific article published on 21 February 2011

Blockade of the IL-1R1/TLR4 pathway mediates disease-modification therapeutic effects in a model of acquired epilepsy.

scientific article published on 9 December 2016

Breast and renal cancer-Derived endothelial colony forming cells share a common gene signature.

scientific article

Brostallicin (PNU-166196)--a new DNA minor groove binder that retains sensitivity in DNA mismatch repair-deficient tumour cells.

scientific article published on October 2003

Characterization of a new trabectedin-resistant myxoid liposarcoma cell line that shows collateral sensitivity to methylating agents.

scientific article

Circulating miRNA landscape identifies miR-1246 as promising diagnostic biomarker in high-grade serous ovarian carcinoma: A validation across two independent cohorts

scientific article published on 22 December 2016

Circulating plasma vascular endothelial growth factor in mice bearing human ovarian carcinoma xenograft correlates with tumor progression and response to therapy

scientific article published on 01 May 2005

DRAGO (KIAA0247), a new DNA damage-responsive, p53-inducible gene that cooperates with p53 as oncosuppressor. [Corrected]

scientific article

Development of distamycin-related DNA binding anticancer drugs.

scientific article

Effect of Aplidin in acute lymphoblastic leukaemia cells.

scientific article published on August 2003

Effects of inducible overexpression of DNp73alpha on cancer cell growth and response to treatment in vitro and in vivo.

scientific article

FOXM1 expression is significantly associated with chemotherapy resistance and adverse prognosis in non-serous epithelial ovarian cancer patients

scientific article

Glutathione influences c-Myc-induced apoptosis in M14 human melanoma cells

scientific article published on 10 September 2002

IGFBP-4 tumor and serum levels are increased across all stages of epithelial ovarian cancer

scientific article published on 20 January 2012

Identification of high-grade serous ovarian cancer miRNA species associated with survival and drug response in patients receiving neoadjuvant chemotherapy: a retrospective longitudinal analysis using matched tumor biopsies.

scientific article published on 17 January 2016

Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743.

scientific article published on June 2000

Lurbinectedin reduces tumour-associated macrophages and the inflammatory tumour microenvironment in preclinical models

scientific article published on 6 July 2017

MAL gene overexpression as a marker of high-grade serous ovarian carcinoma stem-like cells that predicts chemoresistance and poor prognosis

scientific article

Mechanism of action of trabectedin in desmoplastic small round cell tumor cells.

scientific article

MiRNA landscape in stage I epithelial ovarian cancer defines the histotype specificities.

scientific article published on 13 June 2013

Mode of action of trabectedin in myxoid liposarcomas.

scientific article published on 11 November 2013

New molecules and strategies in the field of anticancer agents.

scientific article published on May 2004

Novel models of myxoid liposarcoma xenografts mimicking the biological and pharmacologic features of human tumors.

scientific article published on 20 August 2010

Profiling cancer gene mutations in longitudinal epithelial ovarian cancer biopsies by targeted next-generation sequencing: a retrospective study.

scientific article published on 6 April 2015

Protection of Brain Injury by Amniotic Mesenchymal Stromal Cell-Secreted Metabolites.

scientific article published on 20 July 2016

Resistance to platinum-based chemotherapy is associated with epithelial to mesenchymal transition in epithelial ovarian cancer

article

Role of Macrophage Targeting in the Antitumor Activity of Trabectedin

scientific article published on 01 February 2013

The expression of the DeltaNp73beta isoform of p73 leads to tetraploidy.

scientific article

The zinc finger gene ZIC2 has features of an oncogene and its overexpression correlates strongly with the clinical course of epithelial ovarian cancer

scientific article

Unique features of the mode of action of ET-743.

scientific article

Wiring miRNAs to pathways: a topological approach to integrate miRNA and mRNA expression profiles

scientific article

lncRNAs as Novel Indicators of Patients' Prognosis in Stage I Epithelial Ovarian Cancer: A Retrospective and Multicentric Study.

scientific article

microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial-mesenchymal transition.

scientific article published on January 2014

ΔNp63 expression is associated with poor survival in ovarian cancer

scientific article published on 12 November 2007

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