List of works - Aya Kurosawa

A novel partial agonist of GPBA reduces blood glucose level in a murine glucose tolerance test.

scientific article published on 17 August 2017

Analysis of the role of homology arms in gene-targeting vectors in human cells

scientific article

Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs

scientific article

Both CpG methylation and activation-induced deaminase are required for the fragility of the human bcl-2 major breakpoint region: implications for the timing of the breaks in the t(14;18) translocation

scientific article

Cell sorting analysis of cell cycle-dependent X-ray sensitivity in end joining-deficient human cells

scientific article published on 04 June 2008

Complex genetic interactions between DNA polymerase β and the NHEJ ligase

scientific article published on 29 July 2019

DNA ligase IV and artemis act cooperatively to suppress homologous recombination in human cells: implications for DNA double-strand break repair

scientific article

Functions and regulation of Artemis: a goddess in the maintenance of genome integrity.

scientific article published on 11 June 2010

GPR31 and GPR151 are activated under acidic conditions

scientific article published on 23 May 2019

Heterozygous disruption of the DNA topoisomerase I gene confers cellular resistance to camptothecin in human cells.

scientific article published on April 2009

Human neutrophils isolated from peripheral blood contain Ku protein but not DNA-dependent protein kinase

scientific article published on 01 January 2003

Identification and molecular docking studies for novel inverse agonists of SREB, super conserved receptor expressed in brain

scientific article

Impact of non-homologous end-joining deficiency on random and targeted DNA integration: implications for gene targeting.

scientific article published on 3 October 2008

In vivo and in vitro evaluation of novel μ-opioid receptor agonist compounds.

scientific article published on 14 October 2015

Interference in DNA replication can cause mitotic chromosomal breakage unassociated with double-strand breaks

scientific article

Mechanisms of chromosomal DNA strand break repair in human cells

scientific article published on March 2009

Mechanistic basis for increased human gene targeting by promoterless vectors-roles of homology arms and Rad54 paralogs.

scientific article

Mutations in XRCC4 cause primordial dwarfism without causing immunodeficiency.

scientific article published on 12 May 2016

NK314, a topoisomerase II inhibitor that specifically targets the alpha isoform.

scientific article

Nucleofection-based gene targeting in human pre-B cells ⬇️

scientific article published on November 18, 2011

Overexpression of HAM1 gene detoxifies 5-bromodeoxyuridine in the yeast Saccharomyces cerevisiae.

scientific article

Role for Artemis nuclease in the repair of radiation-induced DNA double strand breaks by alternative end joining.

scientific article published on 25 April 2015

The requirement of Artemis in double-strand break repair depends on the type of DNA damage.

scientific article

List of works by Aya Kurosawa

A novel partial agonist of GPBA reduces blood glucose level in a murine glucose tolerance test.

Analysis of the role of homology arms in gene-targeting vectors in human cells

Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs

Both CpG methylation and activation-induced deaminase are required for the fragility of the human bcl-2 major breakpoint region: implications for the timing of the breaks in the t(14;18) translocation

Cell sorting analysis of cell cycle-dependent X-ray sensitivity in end joining-deficient human cells

Complex genetic interactions between DNA polymerase β and the NHEJ ligase

DNA ligase IV and artemis act cooperatively to suppress homologous recombination in human cells: implications for DNA double-strand break repair

Functions and regulation of Artemis: a goddess in the maintenance of genome integrity.

GPR31 and GPR151 are activated under acidic conditions

Heterozygous disruption of the DNA topoisomerase I gene confers cellular resistance to camptothecin in human cells.

Human neutrophils isolated from peripheral blood contain Ku protein but not DNA-dependent protein kinase

Identification and molecular docking studies for novel inverse agonists of SREB, super conserved receptor expressed in brain

Impact of non-homologous end-joining deficiency on random and targeted DNA integration: implications for gene targeting.

In vivo and in vitro evaluation of novel μ-opioid receptor agonist compounds.

Interference in DNA replication can cause mitotic chromosomal breakage unassociated with double-strand breaks

Mechanisms of chromosomal DNA strand break repair in human cells

Mechanistic basis for increased human gene targeting by promoterless vectors-roles of homology arms and Rad54 paralogs.

Mutations in XRCC4 cause primordial dwarfism without causing immunodeficiency.

NK314, a topoisomerase II inhibitor that specifically targets the alpha isoform.

Nucleofection-based gene targeting in human pre-B cells ⬇️

Overexpression of HAM1 gene detoxifies 5-bromodeoxyuridine in the yeast Saccharomyces cerevisiae.

Role for Artemis nuclease in the repair of radiation-induced DNA double strand breaks by alternative end joining.

The requirement of Artemis in double-strand break repair depends on the type of DNA damage.