List of works - Fabrice Antigny

A functional tandem between transient receptor potential canonical channels 6 and calcium-dependent chloride channels in human epithelial cells.

scientific article published on 8 August 2015

Abnormal spatial diffusion of Ca2+ in F508del-CFTR airway epithelial cells.

scientific article

Activation of transient receptor potential canonical 3 (TRPC3)-mediated Ca2+ entry by A1 adenosine receptor in cardiomyocytes disturbs atrioventricular conduction

scientific article

Bmpr2 Mutant Rats Develop Pulmonary and Cardiac Characteristics of Pulmonary Arterial Hypertension

scientific article published on 01 February 2019

CFTR and Ca Signaling in Cystic Fibrosis.

scientific article published on 25 October 2011

Ca2+ handling remodeling and STIM1L/Orai1/TRPC1/TRPC4 upregulation in monocrotaline-induced right ventricular hypertrophy.

scientific article published on 7 April 2018

Calcium homeostasis is abnormal in cystic fibrosis airway epithelial cells but is normalized after rescue of F508del-CFTR.

scientific article

Calumenin contributes to ER-Ca2+ homeostasis in bronchial epithelial cells expressing WT and F508del mutated CFTR and to F508del-CFTR retention.

scientific article published on 4 February 2017

Chemotherapy-induced pulmonary hypertension: role of alkylating agents.

scientific article

Corrigendum to "A Simple Method to Assess In Vivo Proliferation in Lung Vasculature with EdU: The Case of MMC-Induced PVOD in Rat".

scientific article

During post-natal human myogenesis, normal myotube size requires TRPC1- and TRPC4-mediated Ca²⁺ entry.

scientific article published on 2 April 2013

Endothelial-to-mesenchymal transition in pulmonary hypertension.

scientific article published on 15 January 2015

Evidence for the involvement of type I interferon in pulmonary arterial hypertension

scientific article published on 13 December 2013

Functional interaction between PDGFβ and GluN2B-containing NMDA receptors in smooth muscle cell proliferation and migration in pulmonary arterial hypertension

scientific article published on 13 December 2018

Guanabenz, an alpha2-selective adrenergic agonist, activates Ca2+-dependent chloride currents in cystic fibrosis human airway epithelial cells

scientific article

Implication of Potassium Channels in the Pathophysiology of Pulmonary Arterial Hypertension

scientific article published on 01 September 2020

In vivo miR-138-5p inhibition alleviates monocrotaline-induced pulmonary hypertension and normalizes pulmonary KCNK3 and SLC45A3 expression

scientific article published on 16 July 2020

Inositol 1,4,5 trisphosphate receptor 1 is a key player of human myoblast differentiation

scientific article published on 4 November 2014

Ion Channels in Pulmonary Hypertension: A Therapeutic Interest?

scientific article published on 14 October 2018

KCNK3: new gene target for pulmonary hypertension?

scientific article published on 18 April 2014

Loss of KCNK3 is a hallmark of RV hypertrophy/dysfunction associated with pulmonary hypertension.

scientific article published on 19 January 2018

Maintaining low Ca2+ level in the endoplasmic reticulum restores abnormal endogenous F508del-CFTR trafficking in airway epithelial cells.

scientific article published on May 2006

Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Models

scientific article published on 30 June 2015

NMDA-Type Glutamate Receptor Activation Promotes Vascular Remodeling and Pulmonary Arterial Hypertension.

scientific article published on 14 February 2018

Nebivolol for Improving Endothelial Dysfunction, Pulmonary Vascular Remodeling, and Right Heart Function in Pulmonary Hypertension

scientific article published in February 2015

Potassium Channel Subfamily K Member 3 (KCNK3) Contributes to the Development of Pulmonary Arterial Hypertension.

scientific article published on 24 February 2016

Potassium channels in pulmonary arterial hypertension

scientific article published on 04 September 2015

Proteomic Analysis of KCNK3 Loss of Expression Identified Dysregulated Pathways in Pulmonary Vascular Cells

scientific article published on 07 October 2020

Pulmonary endothelial cell DNA methylation signature in pulmonary arterial hypertension

scientific article published on 19 May 2017

Pulmonary vascular remodeling patterns and expression of general control nonderepressible 2 (GCN2) in pulmonary veno-occlusive disease.

scientific article published on 4 October 2017

Response to Letter Regarding Article, “Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Model”

scientific article published on 01 April 2016

Roscovitine is a proteostasis regulator that corrects the trafficking defect of F508del-CFTR by a CDK-independent mechanism

scientific article

SERCA and PMCA pumps contribute to the deregulation of Ca2+ homeostasis in human CF epithelial cells.

scientific article

STIM1L traps and gates Orai1 channels without remodeling the cortical ER

scientific article published on 3 March 2015

T-type Ca2+ channels elicit pro-proliferative and anti-apoptotic responses through impaired PP2A/Akt1 signaling in PASMCs from patients with pulmonary arterial hypertension

scientific article

TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications.

scientific article published on 9 November 2017

TRPC1 and TRPC4 channels functionally interact with STIM1L to promote myogenesis and maintain fast repetitive Ca2+ release in human myotubes

scientific article

Transient Receptor Potential Canonical (TRPC)/Orai1-dependent Store-operated Ca2+ Channels: NEW TARGETS OF ALDOSTERONE IN CARDIOMYOCYTES.

scientific article published on 22 April 2016

Transient receptor potential canonical channel 6 links Ca2+ mishandling to cystic fibrosis transmembrane conductance regulator channel dysfunction in cystic fibrosis.

scientific article

Transient receptor potential canonical channels are required for in vitro endothelial tube formation.

scientific article published on 27 December 2011

Transient receptor potential vanilloid 1 (TRPV1) channels in cultured rat Sertoli cells regulate an acid sensing chloride channel

scientific journal article

Use of β-Blockers in Pulmonary Hypertension

scientific article published on April 2017

miR-223 reverses experimental pulmonary arterial hypertension

scientific article published on 17 June 2015

List of works by Fabrice Antigny

A functional tandem between transient receptor potential canonical channels 6 and calcium-dependent chloride channels in human epithelial cells.

Abnormal spatial diffusion of Ca2+ in F508del-CFTR airway epithelial cells.

Activation of transient receptor potential canonical 3 (TRPC3)-mediated Ca2+ entry by A1 adenosine receptor in cardiomyocytes disturbs atrioventricular conduction

Bmpr2 Mutant Rats Develop Pulmonary and Cardiac Characteristics of Pulmonary Arterial Hypertension

CFTR and Ca Signaling in Cystic Fibrosis.

Ca2+ handling remodeling and STIM1L/Orai1/TRPC1/TRPC4 upregulation in monocrotaline-induced right ventricular hypertrophy.

Calcium homeostasis is abnormal in cystic fibrosis airway epithelial cells but is normalized after rescue of F508del-CFTR.

Calumenin contributes to ER-Ca2+ homeostasis in bronchial epithelial cells expressing WT and F508del mutated CFTR and to F508del-CFTR retention.

Chemotherapy-induced pulmonary hypertension: role of alkylating agents.

Corrigendum to "A Simple Method to Assess In Vivo Proliferation in Lung Vasculature with EdU: The Case of MMC-Induced PVOD in Rat".

During post-natal human myogenesis, normal myotube size requires TRPC1- and TRPC4-mediated Ca²⁺ entry.

Endothelial-to-mesenchymal transition in pulmonary hypertension.

Evidence for the involvement of type I interferon in pulmonary arterial hypertension

Functional interaction between PDGFβ and GluN2B-containing NMDA receptors in smooth muscle cell proliferation and migration in pulmonary arterial hypertension

Guanabenz, an alpha2-selective adrenergic agonist, activates Ca2+-dependent chloride currents in cystic fibrosis human airway epithelial cells

Implication of Potassium Channels in the Pathophysiology of Pulmonary Arterial Hypertension

In vivo miR-138-5p inhibition alleviates monocrotaline-induced pulmonary hypertension and normalizes pulmonary KCNK3 and SLC45A3 expression

Inositol 1,4,5 trisphosphate receptor 1 is a key player of human myoblast differentiation

Ion Channels in Pulmonary Hypertension: A Therapeutic Interest?

KCNK3: new gene target for pulmonary hypertension?

Loss of KCNK3 is a hallmark of RV hypertrophy/dysfunction associated with pulmonary hypertension.

Maintaining low Ca2+ level in the endoplasmic reticulum restores abnormal endogenous F508del-CFTR trafficking in airway epithelial cells.

Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Models

NMDA-Type Glutamate Receptor Activation Promotes Vascular Remodeling and Pulmonary Arterial Hypertension.

Nebivolol for Improving Endothelial Dysfunction, Pulmonary Vascular Remodeling, and Right Heart Function in Pulmonary Hypertension

Potassium Channel Subfamily K Member 3 (KCNK3) Contributes to the Development of Pulmonary Arterial Hypertension.

Potassium channels in pulmonary arterial hypertension

Proteomic Analysis of KCNK3 Loss of Expression Identified Dysregulated Pathways in Pulmonary Vascular Cells

Pulmonary endothelial cell DNA methylation signature in pulmonary arterial hypertension

Pulmonary vascular remodeling patterns and expression of general control nonderepressible 2 (GCN2) in pulmonary veno-occlusive disease.

Response to Letter Regarding Article, “Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Model”

Roscovitine is a proteostasis regulator that corrects the trafficking defect of F508del-CFTR by a CDK-independent mechanism

SERCA and PMCA pumps contribute to the deregulation of Ca2+ homeostasis in human CF epithelial cells.

STIM1L traps and gates Orai1 channels without remodeling the cortical ER

T-type Ca2+ channels elicit pro-proliferative and anti-apoptotic responses through impaired PP2A/Akt1 signaling in PASMCs from patients with pulmonary arterial hypertension

TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications.

TRPC1 and TRPC4 channels functionally interact with STIM1L to promote myogenesis and maintain fast repetitive Ca2+ release in human myotubes

Transient Receptor Potential Canonical (TRPC)/Orai1-dependent Store-operated Ca2+ Channels: NEW TARGETS OF ALDOSTERONE IN CARDIOMYOCYTES.

Transient receptor potential canonical channel 6 links Ca2+ mishandling to cystic fibrosis transmembrane conductance regulator channel dysfunction in cystic fibrosis.

Transient receptor potential canonical channels are required for in vitro endothelial tube formation.

Transient receptor potential vanilloid 1 (TRPV1) channels in cultured rat Sertoli cells regulate an acid sensing chloride channel

Use of β-Blockers in Pulmonary Hypertension

miR-223 reverses experimental pulmonary arterial hypertension