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List of works by Sascha Hoogendoorn

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

scientific article published on 19 February 2018

A Multivalent Ligand for the Mannose-6-Phosphate Receptor for Endolysosomal Targeting of an Activity-Based Probe

scientific article published on 27 August 2014

Bioorthogonal chemistry: applications in activity-based protein profiling

scientific article published on 28 July 2011

ChemInform Abstract: Hypersensitive Response to Over-Reactive Cysteines

Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity

scientific article

Development of Selective LH Receptor Agonists by Heterodimerization with a FSH Receptor Antagonist

scientific article published on 8 November 2010

Development of an activity-based probe and in silico design reveal highly selective inhibitors for diacylglycerol lipase-α in brain

scientific article published on 31 October 2013

Direct and two-step bioorthogonal probes for Bruton's tyrosine kinase based on ibrutinib: a comparative study.

scientific article

Enantioselective synthesis of adamantylalanine and carboranylalanine and their incorporation into the proteasome inhibitor bortezomib

scientific article published on 19 February 2016

From Phenotypic Hit to Chemical Probe: Chemical Biology Approaches to Elucidate Small Molecule Action in Complex Biological Systems

scientific article published on 03 December 2020

Hypersensitive Response to Over-reactive Cysteines

scientific article published on 13 May 2011

Investigations on therapeutic glucocerebrosidases through paired detection with fluorescent activity-based probes

scientific article

Novel endogenous peptide agonists of cannabinoid receptors

scientific article

Synthesis and Evaluation of Hybrid Structures Composed of Two Glucosylceramide Synthase Inhibitors

scientific article published on 23 October 2015

Synthesis and pharmacological evaluation of dimeric follicle-stimulating hormone receptor antagonists

scientific article published in December 2009

Synthesis of oligoribonucleic acid conjugates using a cyclooctyne phosphoramidite

scientific article published on 4 November 2010

Synthesis of pH-activatable red fluorescent BODIPY dyes with distinct functionalities

scientific article published on 26 September 2011

Targeted Delivery of Fluorescent High-Mannose-Type Oligosaccharide Cathepsin Inhibitor Conjugates

scientific article published on 21 April 2015

Targeted pH-dependent fluorescent activity-based cathepsin probes

scientific article published on 18 July 2011

Two-step bioorthogonal activity-based proteasome profiling using copper-free click reagents: a comparative study

scientific article published on 23 June 2011