List of works - Weijun Shen

A Dual Inhibitor of DYRK1A and GSK3β for β-Cell Proliferation: Aminopyrazine Derivative GNF4877

scientific article published on 02 July 2020

A Novel Role for RARα Agonists as Apolipoprotein CIII Inhibitors Identified from High Throughput Screening

scientific article

A general strategy for synthesis of cyclophane-braced peptide macrocycles via palladium-catalysed intramolecular sp3 C-H arylation

scientific article published on 2 April 2018

A novel inhibitor of inducible NOS dimerization protects against cytokine-induced rat beta cell dysfunction

scientific article published on 14 July 2018

Design and Synthesis of Potent, Long-Acting Lipidated Relaxin-2 Analogs

scientific article published on 13 December 2018

Design of Potent and Proteolytically Stable Oxyntomodulin Analogs

scientific article published on 4 January 2016

Design of a Long-Acting and Selective MEG-Fatty Acid Stapled Prolactin-Releasing Peptide Analog

scientific article published on 05 July 2019

Engineering a Potent, Long-Acting, and Periphery-Restricted Oxytocin Receptor Agonist with Anorexigenic and Body Weight Reducing Effects

scientific article published on 18 December 2019

Engineering a long-acting, potent GLP-1 analog for microstructure-based transdermal delivery

scientific article published on 28 March 2016

Engineering of a Potent, Long-Acting NPY2R Agonist for Combination with a GLP-1R Agonist as a Multi-Hormonal Treatment for Obesity

scientific article published on 26 August 2020

Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.

scientific article published on 26 October 2015

Mini-ISES identifies promising carbafructopyranose-based salens for asymmetric catalysis: Tuning ligand shape via the anomeric effect

scientific article published on 10 July 2015

New Generation Oxyntomodulin Peptides with Improved Pharmacokinetic Profiles Exhibit Weight Reducing and Anti-Steatotic Properties in Mice

scientific article published on 03 April 2020

Overcoming resistance to HER2 inhibitors through state-specific kinase binding

scientific article published on 05 September 2016

Oxysterols direct immune cell migration via EBI2 ⬇️

scientific article published on July 27, 2011

Probing Protein–Protein Interactions with a Genetically Encoded Photo‐crosslinking Amino Acid ⬇️

scientific article published on June 15, 2011

Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6-Azaindole Derivative GNF2133

scientific article published on 20 February 2020

Small-molecule inducer of β cell proliferation identified by high-throughput screening.

scientific article published on 25 January 2013

Stapled, Long-Acting Glucagon-like Peptide 2 Analog with Efficacy in Dextran Sodium Sulfate Induced Mouse Colitis Models

scientific article published on 23 March 2018

Targeted Disruption of Myc-Max Oncoprotein Complex by a Small Molecule.