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List of works by Tatiana Gianni

A Heptad Repeat in Herpes Simplex Virus 1 gH, Located Downstream of the α-Helix with Attributes of a Fusion Peptide, Is Critical for Virus Entry and Fusion.

scientific article

A heptad repeat in herpes simplex virus 1 gH, located downstream of the alpha-helix with attributes of a fusion peptide, is critical for virus entry and fusion

scientific article

Coexpression of UL20p and gK inhibits cell-cell fusion mediated by herpes simplex virus glycoproteins gD, gH-gL, and wild-type gB or an endocytosis-defective gB mutant and downmodulates their cell surface expression

scientific article published on August 2004

Dissociation of HSV gL from gH by αvβ6- or αvβ8-integrin promotes gH activation and virus entry

scientific article published on 8 July 2015

Entry of herpes simplex virus mediated by chimeric forms of nectin1 retargeted to endosomes or to lipid rafts occurs through acidic endosomes

scientific article published on November 2004

Herpes simplex virus glycoproteins H/L bind to cells independently of {alpha}V{beta}3 integrin and inhibit virus entry, and their constitutive expression restricts infection

scientific article

Herpes simplex virus glycoproteins gH/gL and gB bind Toll-like receptor 2, and soluble gH/gL is sufficient to activate NF-κB

scientific article

Insertion of a ligand to HER2 in gB retargets HSV tropism and obviates the need for activation of the other entry glycoproteins.

scientific article

Rescue, Purification, and Characterization of a Recombinant HSV Expressing a Transgenic Protein

scientific article published on 01 January 2020

Retargeting Strategies for Oncolytic Herpes Simplex Viruses

scientific article

Simultaneous Insertion of Two Ligands in gD for Cultivation of Oncolytic Herpes Simplex Viruses in Noncancer Cells and Retargeting to Cancer Receptors

scientific article published on 20 December 2017

The epithelial αvβ3-integrin boosts the MYD88-dependent TLR2 signaling in response to viral and bacterial components

scientific article

The herpesvirus glycoproteins B and H.L are sequentially recruited to the receptor-bound gD to effect membrane fusion at virus entry.

scholarly article

The multipartite system that mediates entry of herpes simplex virus into the cell

scientific article published on September 2007

The soluble ectodomain of herpes simplex virus gD contains a membrane-proximal pro-fusion domain and suffices to mediate virus entry

scientific article

Type I interferon and NF-κB activation elicited by herpes simplex virus gH/gL via αvβ3 integrin in epithelial and neuronal cell lines

scientific article published on 9 October 2013

Viral and cellular contributions to herpes simplex virus entry into the cell

scientific article published on 04 January 2012

oHSV Genome Editing by Means of galK Recombineering

scientific article published on 01 January 2020

αVβ3-integrin relocalizes nectin1 and routes herpes simplex virus to lipid rafts

scientific article

αvβ3 Integrin Boosts the Innate Immune Response Elicited in Epithelial Cells through Plasma Membrane and Endosomal Toll-Like Receptors

scientific article published on 3 February 2016

αvβ3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1.

scientific article

αvβ3-integrin regulates PD-L1 expression and is involved in cancer immune evasion

scientific article published on 16 September 2019

αvβ6- and αvβ8-integrins serve as interchangeable receptors for HSV gH/gL to promote endocytosis and activation of membrane fusion

scientific article