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List of works by Jorg Kotzka

2D-ToGo workflow: increasing feasibility and reproducibility of 2-dimensional gel electrophoresis.

scientific article published on 17 May 2013

A mutation in the c-fos gene associated with congenital generalized lipodystrophy.

scientific article published on 07 August 2013

A novel nonsense mutation in GCK exon 9 co-segregates with diabetes phenotype.

scientific article

A variant of the glucose transporter gene SLC2A2 modifies the glycaemic response to metformin therapy in recently diagnosed type 2 diabetes

article

ADD1/SREBP-1c mediates insulin-induced gene expression linked to the MAP kinase pathway

scientific article published on 01 August 1998

Adipokinome Signatures in Obese Mouse Models Reflect Adipose Tissue Health and Are Associated with Serum Lipid Composition.

scientific article

Alteration of Liver Peroxisomal and Mitochondrial Functionality in the NZO Mouse Model of Metabolic Syndrome.

scientific article published on 25 October 2017

An association between NIDDM and a GAA trinucleotide repeat polymorphism in the X25/frataxin (Friedreich's ataxia) gene

article

Association between copy-number variation on metabolic phenotypes and HDL-C levels in patients with polycystic ovary syndrome

scientific article

Association between the PPARalpha L162V polymorphism, plasma lipoprotein levels, and atherosclerotic disease in patients with diabetes mellitus type 2 and in nondiabetic controls.

scientific article published in June 2004

Associations between explorative dietary patterns and serum lipid levels and their interactions with ApoA5 and ApoE haplotype in patients with recently diagnosed type 2 diabetes

scientific article published on 27 September 2016

CDH13 abundance interferes with adipocyte differentiation and is a novel biomarker for adipose tissue health

scientific article published on 21 February 2018

Characterization of a postreceptor signaling defect that impairs cfos expression in cultured fibroblasts of a patient with insulin resistance

scientific article published on 01 February 2000

Combinatorial hexapeptide ligand libraries (ProteoMiner): an innovative fractionation tool for differential quantitative clinical proteomics

scientific article published in July 2009

Correction of insulin resistance and the metabolic syndrome.

scientific article

Defects of insulin and IGF-1 action at receptor and postreceptor level in a patient with type A syndrome of insulin resistance

scientific article published on 01 May 1997

Divergent phenotypes in siblings with identical novel mutations in the HNF-1α gene leading to maturity onset diabetes of the young type 3

scientific article

Effect of sterol regulatory element binding protein-1a on the mitochondrial protein pattern in human liver cells detected by 2D-DIGE.

scientific article

Endogenous galactose formation in galactose-1-phosphate uridyltransferase deficiency.

scientific article published on 30 September 2014

Enhancing mass spectrometry based serum profiling by a combination of free flow electrophoresis and ClinProt

scientific article published on 01 December 2009

Estrogen receptor-alpha and Sp1 interact in the induction of the low density lipoprotein-receptor

scientific article published on August 2003

Exosomal proteins constitute an essential part of the human adipose tissue secretome

scientific article published on 28 November 2018

Fatty Liver Due to Increased de novo Lipogenesis: Alterations in the Hepatic Peroxisomal Proteome

scientific article published on 25 October 2019

Genetic variants in central metabolic genes influence some but not all relations of inflammatory markers in a collective with polycystic ovary syndrome

scientific article published on 28 June 2012

Genetic variations in SREBP-1 and LXRα are not directly associated to PCOS but contribute to the physiological specifics of the syndrome ⬇️

scientific article published on February 4, 2012

Identification of Mutations of the Arginine Vasopressin-Neurophysin II Gene in Two Kindreds with Familial Central Diabetes Insipidus ⬇️

scientific article published on February 1, 1998

Identification of a gene variant in the master regulator of lipid metabolism SREBP-1 in a family with a novel form of severe combined hypolipidemia

scientific article published on 18 May 2011

Identification of a novel mutation in the arginine vasopressin-neurophysin II gene in familial central diabetes insipidus.

scientific article

Identification of novel adipokines differential regulated in C57BL/Ks and C57BL/6.

scientific article published on 16 October 2014

Identification of the Secreted Proteins Originated from Primary Human Hepatocytes and HepG2 Cells

scientific article published on 03 August 2019

Identification of tyrosine phosphorylation sites in human Gab-1 protein by EGF receptor kinase in vitro.

scientific article

Inactivation of SREBP-1a Phosphorylation Prevents Fatty Liver Disease in Mice: Identification of Related Signaling Pathways by Gene Expression Profiles in Liver and Proteomes of Peroxisomes.

scientific article published on 25 March 2018

Increased low grade inflammatory serum markers in patients with Polycystic ovary syndrome (PCOS) and their relationship to PPARgamma gene variants.

scientific article

Indirect calorimetry in humans: a postcalorimetric evaluation procedure for correction of metabolic monitor variability.

scientific article published on 27 February 2013

Insulin Resistance and Vulnerability to Cardiac Ischemia

scientific article published on 26 September 2018

Insulin-activated Erk-mitogen-activated protein kinases phosphorylate sterol regulatory element-binding Protein-2 at serine residues 432 and 455 in vivo.

scientific article published on 26 February 2004

Insulin-regulated transcription factors: molecular link between insulin resistance and cardiovascular risk factors

scientific article published on 01 May 2001

Investigating the adipose tissue secretome: a protocol to generate high-quality samples appropriate for comprehensive proteomic profiling

scientific article published on 01 January 2015

Isolation and quality control of functional mitochondria.

scientific article published in January 2015

LDL cholesterol--why lower and lower?

scientific article published in May 2007

Lipodystrophies-Disorders of the Fatty Tissue

scientific article published on 20 November 2020

Liver-specific expression of transcriptionally active SREBP-1c is associated with fatty liver and increased visceral fat mass

scientific article

Mechanisms of Insulin Resistance in Primary and Secondary Nonalcoholic Fatty Liver

scientific article

Metabolic syndrome and hypertension: pathophysiology and molecular basis of insulin resistance.

scientific article published in January 1998

Novel Insights into the Adipokinome of Obese and Obese/Diabetic Mouse Models

scientific article published on 8 September 2017

Peroxisome proliferator-activated receptor-gamma2 Pro12Ala and endothelial nitric oxide synthase-4a/b gene polymorphisms are not associated with hypertension in diabetes mellitus type 2.

scientific article published in February 2005

Peroxisomes compensate hepatic lipid overflow in mice with fatty liver

scientific article published on 17 March 2015

Phosphorylation of sterol regulatory element-binding protein (SREBP)-1a links growth hormone action to lipid metabolism in hepatocytes.

scientific article published on 19 August 2010

Phosphorylation of sterol regulatory element-binding protein (SREBP)-1c by p38 kinases, ERK and JNK influences lipid metabolism and the secretome of human liver cell line HepG2.

scientific article

Physiological Disturbance in Fatty Liver Energy Metabolism Converges on IGFBP2 Abundance and Regulation in Mice and Men

scientific article published on 10 June 2020

Preparation of "functional" mitochondria: a challenging business.

scientific article

Preventing phosphorylation of sterol regulatory element-binding protein 1a by MAP-kinases protects mice from fatty liver and visceral obesity

scientific article

Primary skin fibroblasts as human model system for proteome analysis

scientific article published on March 2002

Regulation of the LDL receptor gene expression by hormones

scientific article published on January 1, 1998

Rhein, a novel Histone Deacetylase (HDAC) inhibitor with antifibrotic potency in human myocardial fibrosis

scientific article published on 17 March 2020

Risk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: a 5-year follow-up study

scientific article published on 22 July 2019

SREBP-1: gene regulatory key to syndrome X?

scientific article

Secretome profiling of primary human skeletal muscle cells

scientific article published on 27 August 2013

So close and yet so far: mitochondria and peroxisomes are one but with specific talents.

scientific article

Specific Metabolic Profiles and Their Relationship to Insulin Resistance in Recent-Onset Type 1 and Type 2 Diabetes.

scientific article published on February 2016

Stabilization of atherosclerotic plaque during lipid lowering ⬇️

scientific article published on December 1, 1997

Sterol regulatory element-binding protein (SREBP)-1: gene regulatory target for insulin resistance?

scientific article

The Pro387Leu variant of protein tyrosine phosphatase-1B is not associated with diabetes mellitus type 2 in a German population.

scientific article published in March 2005

The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver

scientific article published on 20 July 2019

The natural history of classic galactosemia: lessons from the GalNet registry

scientific article published on 27 April 2019

Tissue-specific differences in the development of insulin resistance in a mouse model for type 1 diabetes

scientific article

Untargeted mass spectrometric approach in metabolic healthy offspring of patients with type 2 diabetes reveals medium-chain acylcarnitine as potential biomarker for lipid induced glucose intolerance (LGIT).

scientific article

[Combined analyses of paraoxonase-1 and IGF-2 polymorphism in polycystic ovary syndrome]

scientific article published on 06 May 2009

[Lipotoxicity as a new mechanism in metabolic syndrome. Does this explain insulin resistance?]

scientific article

[Mechanisms of plaque stabilization]

scientific article published on 01 February 1999

[Obesity: ectopic fat distribution and the heart]

scientific article published on 01 May 2010

[Plaque stabilization and endothelial protection by cholesterol synthesis inhibitors]

scientific article published on 01 May 1999

[SREBP-1 and fatty liver. Clinical relevance for diabetes, obesity, dyslipidemia and atherosclerosis]

scientific article published on 01 May 2012

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