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List of works by Giuseppe Saccomanni

1,2-Dihydro-2-oxopyridine-3-carboxamides: The C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor

scientific article published on 21 January 2014

1,8-Naphthyridin-4-one derivatives as new ligands of A2A adenosine receptors

scientific article published in October 2005

4-[6-(Dansylamino)hexylamino]-7-methyl-2-phenyl-1,8-naphthyridine as a new potential fluorescent probe for studying A1-adenosine receptor

scientific article published in October 2002

A novel class of highly potent and selective A1 adenosine antagonists: structure-affinity profile of a series of 1,8-naphthyridine derivatives.

scientific article published in July 2000

Adenosine receptor modelling. A1/A2a selectivity

scientific article published on 19 January 2006

Biopharmaceutical profile of tramadol in the dog.

scientific article published in September 2009

CB2-selective cannabinoid receptor ligands: synthesis, pharmacological evaluation, and molecular modeling investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides

scientific article

Cannabinoid CB2/CB1 selectivity. Receptor modeling and automated docking analysis

scientific article

Carbazole-containing arylcarboxamides as BACE1 inhibitors

scientific article published on 21 September 2011

Design, synthesis and preliminary evaluation of 18F-labelled 1,8-naphthyridin- and quinolin-2-one-3-carboxamide derivatives for PET imaging of CB2 cannabinoid receptor

scientific article published on 25 April 2015

Design, synthesis, and biological evaluation of new 1,8-naphthyridin-4(1H)-on-3-carboxamide and quinolin-4(1H)-on-3-carboxamide derivatives as CB2 selective agonists

scientific article published in October 2006

Determination of tramadol and metabolites by HPLC-FL and HPLC-MS/MS in urine of dogs.

scientific article published on 20 March 2010

Determination of water-soluble vitamins in multivitamin dietary supplements and in artichokes by micellar electrokinetic chromatography

scientific article published on 03 June 2013

Development of an HPLC/UV assay for the evaluation of inhibitors of human recombinant monoacylglycerol lipase.

scientific article

Effects on immune cells of a new 1,8-naphthyridin-2-one derivative and its analogues as selective CB2 agonists: implications in multiple sclerosis

scientific article

Evaluation of tramadol and its main metabolites in horse plasma by high-performance liquid chromatography/fluorescence and liquid chromatography/electrospray ionization tandem mass spectrometry techniques

scientific article

High performance liquid chromatographic determination of thalidomide in patients affected by hepatocellular carcinoma

scientific article

Identification of chemical byproducts in the radiofluorination of structurally complex aryliodonium salts

Immune-modulation and properties of absorption and blood brain barrier permeability of 1,8-naphthyridine derivatives

scientific article published in October 2013

Microfluidic approach for fast labeling optimization and dose-on-demand implementation

scientific article published on 24 April 2010

Modified RP-LC of Phenylthiocarbamyl Amino Acid Adducts in Plasma Acetonitrile Extracts Using Multiple Internal Standards and Photo-Diode UV Detection

article published in 2010

New 1,8-naphthyridine and quinoline derivatives as CB2 selective agonists

scientific article

New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity

scientific article published on 24 April 2015

Pharmacokinetic and urine profile of tramadol and its major metabolites following oral immediate release capsules administration in dogs.

scientific article

Pharmacokinetic evaluation of tramadol and its major metabolites after single oral sustained tablet administration in the dog: a pilot study

scientific article published on 3 March 2008

Pharmacokinetics of Tramadol and Its Metabolites M1, M2, and M5 in Donkeys after Intravenous and Oral Immediate Release Single-Dose Administration

article published in 2009

Pharmacokinetics of Tramadol and its Metabolites M1, M2 and M5 in Horses Following Intravenous, Immediate Release (Fasted/Fed) and Sustained Release Single Dose Administration

Pharmacokinetics of intravenous and intramuscular parecoxib in healthy Beagles ⬇️

scientific article published on November 29, 2011

Pharmacokinetics of tramadol and metabolites after injective administrations in dogs ⬇️

scientific article published on January 1, 2010

Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold.

scientific article

Rational design, synthesis, and pharmacological properties of new 1,8-naphthyridin-2(1H)-on-3-carboxamide derivatives as highly selective cannabinoid-2 receptor agonists

scientific article

Simultaneous detection and quantification of parecoxib and valdecoxib in canine plasma by HPLC with spectrofluorimetric detection: development and validation of a new methodology.

scientific article published on 19 July 2011

Structure-Based Virtual Screening: Identification of Novel CB2 Receptor Ligands

Study on affinity profile toward native human and bovine adenosine receptors of a series of 1,8-naphthyridine derivatives

scientific article

Synthesis and antiplatelet activity of some 2,7-di(N-cycloamino)-3-phenyl-1,8-naphthyridine derivatives.

scientific article published in April 2001

Synthesis and antiplatelet activity of some 3-phenyl-1,8-naphthyridine derivatives.

scientific article

Synthesis and beta-blocking activity of (R,S)-(E)-oximeethers of 2,3-dihydro-1,8-naphthyridine and 2,3-dihydrothiopyrano[2,3-b]pyridine: identification of beta 3-antagonists

scientific article published in November 2003

Synthesis and biological evaluation of 1,8-naphthyridin-4(1H)-on-3-carboxamide derivatives as new ligands of cannabinoid receptors

scientific article published in April 2004

Synthesis and evaluation of antihypertensive activity of 1,8-naphthyridine derivatives. Part X.

scientific article published in November 2001

Synthesis and β-blocking activity of (R,S)-(E)-oximeethers of 2,3-dihydro-1,8-naphthyridine and 2,3-dihydrothiopyrano[2,3-b]pyridine:potential antihypertensive agents – Part IX

scientific article published on 01 September 2000

Synthesis of 1,8-naphthyridine derivatives: Potential antihypertensive agents — Part VII

Synthesis of 1,8-naphthyridine derivatives: potential antihypertensive agents – Part VIII

Synthesis of 3- or 4-phenyl-1,8-naphthyridine derivatives and evaluation of antimycobacterial and antimicrobial activity

scientific article published in September 2003

Synthesis of variously substituted 1,8-naphthyridine derivatives and evaluation of their antimycobacterial activity

scientific article published in August 2002

Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands

scientific article published on 02 December 2014

Taurine in women with a history of gestational diabetes

scientific article

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