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List of works by Andrea Sacconi

AMPK β1 reduces tumor progression and improves survival in p53 null mice.

scientific article published on 24 May 2017

Altered peritumoral microRNA expression predicts head and neck cancer patients with a high risk of recurrence.

scientific article published on 21 July 2017

Analytical considerations for mass spectrometry profiling in serum biomarker discovery

scientific article

Antibody Array as a Tool for Screening of Natural Agents in Cancer Chemoprevention

scientific article published on 01 January 2016

Argonaute 2 drives miR-145-5p-dependent gene expression program in breast cancer cells

article

Cdx2 polymorphism affects the activities of vitamin D receptor in human breast cancer cell lines and human breast carcinomas

scientific article

Circulating miR-21-5p and miR-148a-3p as emerging non-invasive biomarkers in thymic epithelial tumors

scientific article published on 17 November 2015

Cynara scolymus affects malignant pleural mesothelioma by promoting apoptosis and restraining invasion ⬇️

scientific article

Downregulation of microRNAs 145-3p and 145-5p is a long-term predictor of postmenopausal breast cancer risk: The ORDET prospective study

scientific article published on 29 July 2014

Dropwort-induced metabolic reprogramming restrains YAP/TAZ/TEAD oncogenic axis in mesothelioma

scientific article published on 09 August 2019

Epigenetic silencing of miR-145-5p contributes to brain metastasis

scientific article published on 30 September 2015

Epigenetic silencing of miR-296 and miR-512 ensures hTERT dependent apoptosis protection and telomere maintenance in basal-type breast cancer cells.

scientific article published on 23 September 2017

Expression of TP53 mutation-associated microRNAs predicts clinical outcome in head and neck squamous cell carcinoma patients.

scientific article published on 09 October 2013

Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression

scientific article published on March 2015

Hippo and rassf1a Pathways: A Growing Affair

scientific article published on 5 July 2012

In vitro antineoplastic effects of brivaracetam and lacosamide on human glioma cells

scientific article

Long Non-coding MIR205HG Depletes Hsa-miR-590-3p Leading to Unrestrained Proliferation in Head and Neck Squamous Cell Carcinoma.

scientific article published on 12 February 2018

MCM7 and its hosted miR-25, 93 and 106b cluster elicit YAP/TAZ oncogenic activity in lung cancer.

scientific article published on 17 October 2016

May predictors of difficulty in thyroid surgery increase the incidence of complications? Prospective study with the proposal of a preoperative score

scientific article published on 24 April 2019

Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC.

scientific article published on 29 May 2012

Metformin-induced ablation of microRNA 21-5p releases Sestrin-1 and CAB39L antitumoral activities.

scientific article

Metformin-induced metabolic reprogramming of chemoresistant ALDHbright breast cancer cells

scientific article

Metformin-induced reductions in tumor growth involves modulation of the gut microbiome

publication published on 20 April 2022

MiR-204 down-regulation elicited perturbation of a gene target signature common to human cholangiocarcinoma and gastric cancer

scientific article

MiRNA-513a-5p Inhibits Progesterone Receptor Expression and Constitutes a Risk Factor For Breast Cancer: The ORDET Prospective Study.

scientific article

MicroRNA expression as predictor of local recurrence risk in oral squamous cell carcinoma.

scientific article published on 24 June 2015

MicroRNA expression profiling of thymic epithelial tumors.

scientific article published on 29 April 2014

MicroRNA signature in metastatic colorectal cancer patients treated with anti-EGFR monoclonal antibodies

scientific article

MicroRNA-128-3p-mediated depletion of Drosha promotes lung cancer cell migration.

scientific article published in February 2018

MicroRNA-driven deregulation of cytokine expression helps development of drug resistance in metastatic melanoma.

scientific article

Multitargeting activity of miR-24 inhibits long-term melatonin anticancer effects

scientific article published on 08 March 2016

PI3K Inhibitors Curtail MYC-dependent Mutant p53 Gain-of-function in Head and Neck Squamous Cell Carcinoma

scientific article published on 22 January 2020

PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer

scientific article published on 21 February 2017

Paracrine Signaling from Breast Cancer Cells Causes Activation of ID4 Expression in Tumor-Associated Macrophages

scientific article published on 11 February 2020

Pharmacokinetics of gemcitabine at fixed-dose rate infusion in patients with normal and impaired hepatic function

scientific article published in January 2009

Protumorigenic effects of mir-145 loss in malignant pleural mesothelioma.

scientific article

Reduction of estradiol in human malignant pleural mesothelioma tissues may prevent tumour growth, as implied by in in-vivo and in-vitro models

scientific article published on 13 June 2016

Serum miR-22 as potential non-invasive predictor of poor clinical outcome in newly diagnosed, uniformly treated patients with diffuse large B-cell lymphoma: an explorative pilot study.

scientific article published on 2 May 2018

Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model

scientific article published in Scientific Reports

The miR-205-5p/BRCA1/RAD17 Axis Promotes Genomic Instability in Head and Neck Squamous Cell Carcinomas

scientific article published on 11 September 2019

The oncogenic role of circPVT1 in head and neck squamous cell carcinoma is mediated through the mutant p53/YAP/TEAD transcription-competent complex.

scientific article published on 20 December 2017

Thymic Epithelial Tumors phenotype relies on miR-145-5p epigenetic regulation

scientific article

Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells

scientific article published on 03 August 2018

Wild type- and mutant p53 proteins in mitochondrial dysfunction: emerging insights in cancer disease

scientific article published on 23 May 2019

hMENA is a key regulator in endothelin-1/β-arrestin1-induced invadopodial function and metastatic process.

scientific article published on 8 February 2018

miR-155 drives telomere fragility in human breast cancer by targeting TRF1.

scientific article published on 29 May 2014

miR-181c associates with tumor relapse of high grade osteosarcoma

scientific article

miR-204 targets Bcl-2 expression and enhances responsiveness of gastric cancer ⬇️

scientific article published on November 15, 2012

miR-30a inhibits endothelin A receptor and chemoresistance in ovarian carcinoma

scientific article published on 10 December 2015

miR-96-5p targets PTEN expression affecting radio-chemosensitivity of HNSCC cells

scientific article published on 29 March 2019

p95HER2 truncated form in resected non-small cell lung cancer

scientific article

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