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List of works by Inge R Holtman

A novel microglial subset plays a key role in myelinogenesis in developing brain

scientific article published on 28 September 2017

Activation of an immune-regulatory macrophage response and inhibition of lung inflammation in a mouse model of COPD using heat-shock protein alpha B-crystallin-loaded PLGA microparticles.

scientific article

Aging, microglia and cytoskeletal regulation are key factors in the pathological evolution of the APP23 mouse model for Alzheimer's disease.

scientific article published on 9 November 2016

Alpha-B-crystallin induces an immune-regulatory and antiviral microglial response in preactive multiple sclerosis lesions

scientific article

An environment-dependent transcriptional network specifies human microglia identity

scientific article published on 25 May 2017

Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function.

scientific article published on 17 May 2018

Brain cell type-specific enhancer-promoter interactome maps and disease-risk association

scientific article published on 14 November 2019

CD14 is a key organizer of microglial responses to CNS infection and injury

scientific article published on 18 December 2015

Demyelination during multiple sclerosis is associated with combined activation of microglia/macrophages by IFN-γ and alpha B-crystallin

scientific article published on 5 July 2014

Enhanced microglial pro-inflammatory response to lipopolysaccharide correlates with brain infiltration and blood-brain barrier dysregulation in a mouse model of telomere shortening.

scientific article published on 3 August 2015

Glia Open Access Database (GOAD): A comprehensive gene expression encyclopedia of glia cells in health and disease.

scientific article

Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.

scientific article

Identification of a conserved and acute neurodegeneration-specific microglial transcriptome in the zebrafish.

scientific article

Identification of highly connected hub genes in the protective response program of human macrophages and microglia activated by alpha B-crystallin

scientific article published on 7 January 2017

Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease

scientific article

Increased White Matter Inflammation in Aging- and Alzheimer's Disease Brain

scientific article

Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis.

scientific article published on 23 May 2015

Lymphocryptovirus Infection of Nonhuman Primate B Cells Converts Destructive into Productive Processing of the Pathogenic CD8 T Cell Epitope in Myelin Oligodendrocyte Glycoprotein

scientific article published on 13 July 2016

Next generation transcriptomics and genomics elucidate biological complexity of microglia in health and disease.

scientific article published on 04 June 2015

Priming of microglia in a DNA-repair deficient model of accelerated aging.

scientific article

Transcriptional control of microglia phenotypes in health and disease.

scientific article

Transcriptomic analysis of purified human cortical microglia reveals age-associated changes

scientific article

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