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List of works by Dawn Bowdish

A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease.

scientific article published on May 2017

A guide to bioinformatics for immunologists

scientific article

A macrophage-stimulating compound from a screen of microbial natural products.

scientific article

A naturally occurring transcript variant of MARCO reveals the SRCR domain is critical for function.

scientific article

A re-evaluation of the role of host defence peptides in mammalian immunity.

scientific article

A278 ESCHERICHIA ABUNDANCE AND LOW FECAL BUTYRATE IN CHILDREN WITH INTESTINAL FAILURE

scholarly article by J K Dowhaniuk et al published 1 February 2018 in Journal of the Canadian Association of Gastroenterology

Adenovirus E1A directly targets the E2F/DP-1 complex

scientific article published on 29 June 2011

Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction

scientific article published on 01 April 2018

Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction.

scientific article

Age-associated metabolic dysregulation in bone marrow-derived macrophages stimulated with lipopolysaccharide

scientific article published on 04 March 2016

Alterations to the frequency and function of peripheral blood monocytes and associations with chronic disease in the advanced-age, frail elderly

scientific article

Amphiregulin-producing γδ T cells are vital for safeguarding oral barrier immune homeostasis

article published in the Proceedings of the National Academy of Sciences of the United States of America

An Introduction to Automated Flow Cytometry Gating Tools and Their Implementation

scientific article (publication date: 2015)

An accessory to the 'Trinity': SR-As are essential pathogen sensors of extracellular dsRNA, mediating entry and leading to subsequent type I IFN responses

scientific article

An investigation of scavenger receptor A mediated leukocyte binding to polyanionic and uncharged polymer hydrogels.

scientific article

Anti-endotoxin properties of cationic host defence peptides and proteins

scientific article

Anti-pneumococcal deficits of monocyte-derived macrophages from the advanced-age, frail elderly and related impairments in PI3K-AKT signaling

scientific article published on 13 October 2014

Apoptosis of airway epithelial cells: human serum sensitive induction by the cathelicidin LL-37.

scientific article published on 9 December 2005

Bacterial Binding, Phagocytosis, and Killing: Measurements Using Colony Forming Units.

scientific article published on January 2017

Blood CD33(+)HLA-DR(-) myeloid-derived suppressor cells are increased with age and a history of cancer

scientific article published on 22 January 2013

Broadly Neutralizing Hemagglutinin Stalk-Specific Antibodies Induce Potent Phagocytosis of Immune Complexes by Neutrophils in an Fc-Dependent Manner

scientific article

CD312, the human adhesion-GPCR EMR2, is differentially expressed during differentiation, maturation, and activation of myeloid cells.

scientific article published on 12 December 2006

Characterization of inflammatory responses during intranasal colonization with Streptococcus pneumoniae.

scientific article

Cigarette Smoke Attenuates the Nasal Host Response to Streptococcus pneumoniae and Predisposes to Invasive Pneumococcal Disease in Mice

scientific article

Circulating TNF and mitochondrial DNA are major determinants of neutrophil phenotype in the advanced-age, frail elderly

scientific article published on 5 February 2015

Circulating muramyl dipeptide is negatively associated with interleukin-10 in the frail elderly.

scientific article published on February 2015

Class A Scavenger Receptor-Mediated Double-Stranded RNA Internalization Is Independent of Innate Antiviral Signaling and Does Not Require Phosphatidylinositol 3-Kinase Activity

scientific article published on 11 September 2015

Collapsing the Proton Motive Force to Identify Synergistic Combinations against Staphylococcus aureus ⬇️

scientific article published on August 22, 2013

Commensal microbiota induces colonic barrier structure and functions that contribute to homeostasis

scientific article published in Scientific Reports

Composition and immunological significance of the upper respiratory tract microbiota.

scientific article

Comprehensive and simultaneous coverage of lipid and polar metabolites for endogenous cellular metabolomics using HILIC-TOF-MS

scientific article

Conserved domains of the class A scavenger receptors: evolution and function

scientific article published on January 2009

Correction: Microneutralization Assay Titres Correlate with Protection against Seasonal Influenza H1N1 and H3N2 in Children

scientific article published on 22 September 2016

Culture and molecular-based profiles show shifts in bacterial communities of the upper respiratory tract that occur with age.

scientific article published on 9 January 2015

Culture and molecular-based profiles show shifts in bacterial communities of the upper respiratory tract that occur with age.

scientific article published on May 2015

DNA methylation patterns are related to co-morbidity status and circulating C-reactive protein levels in the nursing home elderly

scientific article

Dupilumab, Severe Asthma Airway Responses, and SARS-CoV2 Serology

scientific article published on 06 August 2020

Early Omicron infection is associated with increased reinfection risk in older adults in long-term care and retirement facilities

scientific article published in 2023

Editorial: you give me fever: transcriptional responses to LPS

scientific article published on 01 August 2014

Erythro-VLPs: Anchoring SARS-CoV-2 spike proteins in erythrocyte liposomes

scientific article published on 11 March 2022

Exercise reduces depression and inflammation but intensity matters.

scientific article published on 3 February 2018

G-protein-coupled receptor independent, immunomodulatory properties of chemokine CXCL9.

scientific article

HIV-1 gp120 induces TLR2- and TLR4-mediated innate immune activation in human female genital epithelium

scientific article published on 16 September 2013

Heat shock protein-27 attenuates foam cell formation and atherogenesis by down-regulating scavenger receptor-A expression via NF-κB signaling

scientific article published on 11 August 2013

Histone deacetylase activity and recurrent bacterial bronchitis in severe eosinophilic asthma

scientific article published on 30 December 2015

Host cytokine responses distinguish invasive from airway isolates of the Streptococcus milleri/anginosis group

scientific article

Host defence peptide LL-37 induces IL-6 expression in human bronchial epithelial cells by activation of the NF-kappaB signaling pathway.

scientific article

Host defense peptide LL-37, in synergy with inflammatory mediator IL-1beta, augments immune responses by multiple pathways

scientific article published on 01 December 2007

Human-Specific Mutations and Positively Selected Sites in MARCO Confer Functional Changes.

scientific article published on 20 November 2017

IFN-β signalling regulates RAW 264.7 macrophage activation, cytokine production, and killing activity

scientific article published on 15 October 2019

IL-17A and the Promotion of Neutrophilia in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

scientific article published on 3 June 2015

IRAK-4 mutation (Q293X): rapid detection and characterization of defective post-transcriptional TLR/IL-1R responses in human myeloid and non-myeloid cells

scientific article

Immune inhibitory ligand CD200 induction by TLRs and NLRs limits macrophage activation to protect the host from meningococcal septicemia

scientific article published on 01 September 2010

Immunogenicity of Varicella Vaccine and Immunologic Predictors of Response in a Cohort of Elderly Nursing Home Residents.

scientific article published on 5 October 2016

Immunomodulatory activities of small host defense peptides

scientific article

Immunomodulatory properties of defensins and cathelicidins

scientific article

Immunosenescence and novel vaccination strategies for the elderly.

scientific article published on 28 June 2013

Impact of LL-37 on anti-infective immunity.

scientific article

Indigenous enteric eosinophils control DCs to initiate a primary Th2 immune response in vivo

scientific article

Infection in an aging population.

scientific article published on 10 December 2015

Interferon-β induced in female genital epithelium by HIV-1 glycoprotein 120 via Toll-like-receptor 2 pathway acts to protect the mucosal barrier.

scientific article published on 19 March 2018

Lasting Changes to Circulating Leukocytes in People with Mild SARS-CoV-2 Infections

scientific article published in 2021

Latent TGF-β1 is compartmentalized between blood and seminal plasma of HIV-positive men and its activation in semen is negatively correlated with viral load and immune activation

scientific article

Lateral diffusion of CD14 and TLR2 in macrophage plasma membrane assessed by raster image correlation spectroscopy and single particle tracking

scientific article published on 09 November 2020

Length of dsRNA (poly I:C) drives distinct innate immune responses, depending on the cell type

scientific article published on 2 August 2013

Loss of Microbial Topography Precedes Infection in Infants

scientific article published on 01 September 2019

MARCO is required for TLR2- and Nod2-mediated responses to Streptococcus pneumoniae and clearance of pneumococcal colonization in the murine nasopharynx.

scientific article

MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis

scientific article

Macrophage receptors implicated in the "adaptive" form of innate immunity.

scientific article published on 14 September 2007

Metabolic and transcriptomic profiling of Streptococcus intermedius during aerobic and anaerobic growth

scientific article published in 2016

MicroRNA-155 is required for clearance of Streptococcus pneumoniae from the nasopharynx.

scientific article published on 25 August 2014

Microbial dysbiosis and mortality during mechanical ventilation: a prospective observational study

article

Microneutralization assay titres correlate with protection against seasonal influenza H1N1 and H3N2 in children.

scientific article published on 24 June 2015

Microvesicles: ubiquitous contributors to infection and immunity

scientific article

Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37.

scientific article published on February 2006

Monocyte activation is elevated in women with knee-osteoarthritis and associated with inflammation, BMI and pain

scientific article published on 8 November 2017

Mycoplasma pneumoniae, a trigger for Weston Hurst syndrome.

scientific article published on 21 January 2016

Myeloid-derived suppressor cells, age and cancer.

scientific article published on 30 April 2013

Nasal Tissue Extraction Is Essential for Characterization of the Murine Upper Respiratory Tract Microbiota

scientific article published in 2020

Obesity during pregnancy results in maternal intestinal inflammation, placental hypoxia, and alters fetal glucose metabolism at mid-gestation

scientific article published on 26 November 2019

On-going Mechanical Damage from Mastication Drives Homeostatic Th17 Cell Responses at the Oral Barrier

scientific article published on 6 January 2017

Partitioning and correlating subgroup characteristics from Aligned Pattern Clusters.

scientific article published on 22 April 2016

Positive Selection of a Serine Residue in Bat IRF3 Confers Enhanced Antiviral Protection

scientific article published on 02 March 2020

Privileged Antigen Presentation in Splenic B Cell Follicles Maximizes T Cell Responses in Prime-Boost Vaccination.

scientific article

Probiotics to Prevent Respiratory Infections in Nursing Homes: A Pilot Randomized Controlled Trial.

scientific article

Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial-PROSPECT: a pilot trial

scientific article published on 02 August 2016

Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial-PROSPECT: protocol for a feasibility randomized pilot trial

scientific article published on 24 May 2015

Serum C-Reactive Protein and Congestive Heart Failure as Significant Predictors of Herpes Zoster Vaccine Response in Elderly Nursing Home Residents

scientific article published on July 2017

Single cell and tissue-transcriptomic analysis of murine bladders reveals age- and TNFα-dependent but microbiota-independent tertiary lymphoid tissue formation

scientific article published on 04 May 2020

Standardizing scavenger receptor nomenclature

scientific article

Starving the Gut: A Deficit of Butyrate in the Intestinal Ecosystem of Children With Intestinal Failure

scientific article published on 22 October 2019

Streptococcus pneumoniae Colonization Disrupts the Microbial Community within the Upper Respiratory Tract of Aging Mice

scientific article published on 19 January 2016

Streptococcus pneumoniae colonization is required to alter the nasal microbiota in cigarette smoke-exposed mice.

scientific article

TNF Drives Monocyte Dysfunction with Age and Results in Impaired Anti-pneumococcal Immunity.

scientific article published on 14 January 2016

TNF, but not hyperinsulinemia or hyperglycemia, is a key driver of obesity-induced monocytosis revealing that inflammatory monocytes correlate with insulin in obese male mice

scientific article published on 01 December 2018

Targeting macrophage scavenger receptor 1 promotes insulin resistance in obese male mice

scientific article published on 01 November 2018

The Aging Lung: Is Lung Health Good Health for Older Adults?

scientific article published on 22 September 2018

The Evolution of the Scavenger Receptor Cysteine-Rich Domain of the Class A Scavenger Receptors

scientific article published on 6 July 2015

The Gut Microbiota and Unhealthy Aging: Disentangling Cause from Consequence

scientific article published on 01 August 2020

The Molecular Structure of Human Red Blood Cell Membranes from Highly Oriented, Solid Supported Multi-Lamellar Membranes.

scientific article published on 03 January 2017

The cationic antimicrobial peptide LL-37 modulates dendritic cell differentiation and dendritic cell-induced T cell polarization

scientific article published on 01 January 2004

The evolution of the class A scavenger receptors

scientific article

The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses

scientific article published on October 2002

The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system.

scientific article published on 22 June 2006

The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes

scientific article published on March 2004

The loss of topography in the microbial communities of the upper respiratory tract in the elderly.

scientific article

The macrophage.

scientific article published on January 2012

The polyfunctionality of human memory CD8+ T cells elicited by acute and chronic virus infections is not influenced by age

scientific article

The relation between DNA methylation patterns and serum cytokine levels in community-dwelling adults: a preliminary study

scientific article

The sil Locus in Streptococcus Anginosus Group: Interspecies Competition and a Hotspot of Genetic Diversity

scientific article published on January 2016

The unique immunological features of heparin-induced thrombocytopenia.

scientific article

Tumor necrosis factor drives increased splenic monopoiesis in old mice.

scientific article published on April 2016

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