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List of works by Douglas Hooper

Acetylation of human mitochondrial citrate carrier modulates mitochondrial citrate/malate exchange activity to sustain NADPH production during macrophage activation

article

Altered circadian relationship between serum nitric oxide, carbon dioxide, and uric acid in multiple sclerosis.

scientific article published in July 2004

Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells.

scientific article published on 19 October 2016

Brain tissue-resident immune memory cells are required for long-term protection against CNS infection with rabies virus

scientific article published on 01 November 2020

Characterization of a unique variant of bat rabies virus responsible for newly emerging human cases in North America

scientific article published on May 1996

Circadian variation in oxidative stress markers in healthy and type II diabetic men.

scientific article published in March 2002

Clearance of attenuated rabies virus from brain tissues is required for long-term protection against CNS challenge with a pathogenic variant

scientific article published on 09 July 2018

Comparison of uric acid and ascorbic acid in protection against EAE.

scientific article published on November 2002

Development of a reverse genetics system for a human rabies virus vaccine strain employed in China.

scientific article

Differential Host Immune Responses after Infection with Wild-Type or Lab-Attenuated Rabies Viruses in Dogs.

scientific article published on 20 August 2015

Differential expression of growth factors at the cellular level in virus-infected brain

scientific article

Early blood-brain barrier permeability in cerebella of PLSJL mice immunized with myelin basic protein.

scientific article published on 11 April 2008

Effect of mercaptoethylguanidine scavengers of peroxynitrite on the development of experimental allergic encephalomyelitis in PLSJL mice.

scientific article published in September 2001

Effect of rabies virus infection on gene expression in mouse brain

scholarly article

Effective preexposure and postexposure prophylaxis of rabies with a highly attenuated recombinant rabies virus

scientific article published on 06 July 2009

Expression of C1q, a subcomponent of the rat complement system, is dramatically enhanced in brains of rats with either Borna disease or experimental allergic encephalomyelitis

scientific article published on 01 May 1995

Expression of interferon gamma by a recombinant rabies virus strongly attenuates the pathogenicity of the virus via induction of type I interferon.

scientific article

High level expression of a human rabies virus-neutralizing monoclonal antibody by a rhabdovirus-based vector.

scientific article published in June 2001

Human diploid cell culture rabies vaccine (HDCV) and purified chick embryo cell culture rabies vaccine (PCECV) both confer protective immunity against infection with the silver-haired bat rabies virus strain (SHBRV).

scientific article

Human parechovirus and enterovirus initiate distinct CNS innate immune responses: Pathogenic and diagnostic implications.

scientific article

ICAM-1 upregulation in the spinal cords of PLSJL mice with experimental allergic encephalomyelitis is dependent upon TNF-alpha production triggered by the loss of blood-brain barrier integrity

scientific article published on 01 October 2004

IL-4(-/-) mice with lethal Mesocestoides corti infections--reduced Th2 cytokines and alternatively activated macrophages

scientific article published on 01 December 2009

Immune biomarkers of treatment failure for a patient on a phase I clinical trial of pembrolizumab plus radiotherapy.

scientific article published on 23 September 2016

Immunization against rabies with plant-derived antigen

scientific article published in March 1998

Inhibition of hypochlorous acid-induced cellular toxicity by nitrite

scientific article

Intramuscular inoculation of mice with the live-attenuated recombinant rabies virus TriGAS results in a transient infection of the draining lymph nodes and a robust, long-lasting protective immune response against rabies.

scientific article published on 28 November 2012

Limited brain metabolism changes differentiate between the progression and clearance of rabies virus

scientific article

Modulation of serum uric acid levels by inosine in patients with multiple sclerosis does not affect blood pressure.

scientific article published on 29 October 2009

Murine T cells reactive against autologous erythrocytes: evidence for in vitro and in vivo priming with mouse and rat red blood cells

scientific article published on 01 April 1987

Murine pregnancy-associated modulations in lymphocyte reactivity to mitogens: identification of the cell populations affected

scientific article published on 01 August 1987

Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis ⬇️

scientific article published on April 24, 2011

Peroxynitrite-induced oligodendrocyte toxicity is not dependent on poly(ADP-ribose) polymerase activation.

scientific article

Plant vaccines: an immunological perspective.

scientific article published on January 2009

Poly(ADP-ribose) polymerase activity contributes to peroxynitrite-induced spinal cord neuronal cell death in vitro.

scientific article published in September 2004

Postexposure Treatment with the Live-Attenuated Rabies Virus (RV) Vaccine TriGAS Triggers the Clearance of Wild-Type RV from the Central Nervous System (CNS) through the Rapid Induction of Genes Relevant to Adaptive Immunity in CNS Tissues ⬇️

scientific article published on January 11, 2012

Potential role of CSF cytokine profiles in discriminating infectious from non-infectious CNS disorders

scientific article published in PLoS ONE

Pre- and post-exposure safety and efficacy of attenuated rabies virus vaccines are enhanced by their expression of IFNγ

scientific article

Presence of virus neutralizing antibodies in cerebral spinal fluid correlates with non-lethal rabies in dogs

scientific article

Prevention of experimental allergic encephalomyelitis by targeting nitric oxide and peroxynitrite: implications for the treatment of multiple sclerosis

scientific article

Prospects for the treatment of multiple sclerosis by raising serum levels of uric acid, a scavenger of peroxynitrite

scientific article published on 01 January 2001

Protection of myelin basic protein immunized mice from free-radical mediated inflammatory cell invasion of the central nervous system by the natural peroxynitrite scavenger uric acid

scientific article published on 01 October 2000

Rabies virus clearance from the central nervous system.

scientific article published on January 2011

Rabies virus quasispecies: implications for pathogenesis

scientific article

Reactive oxygen/nitrogen species at the fulcrum of life–death decisions: A commentary on “Peroxynitrite transforms nerve growth factor into an apoptotic factor for motor neurons”

scientific article published on 23 September 2006

Regulation on murine T cell responses to autologous antigens by alpha-fetoprotein

scientific article published on 01 September 1981

Self-tolerance for erythrocytes is not maintained by clonal deletion of T helper cells

scientific article published on 01 January 1987

Serum and cerebrospinal fluid uric acid levels in multiple sclerosis patients

scientific article published on 08 May 2008

Serum exosomes and cytokines promote a T-helper cell type 2 environment in the peripheral blood of glioblastoma patients

scientific article published on 14 July 2015

Spleen cells from antigen-minimized mice are superior to spleen cells from germ-free and conventional mice in the stimulation of primary in vitro proliferative responses to nominal antigens

scientific article published on 01 January 1995

T-bet Is Required for the Rapid Clearance of Attenuated Rabies Virus from Central Nervous System Tissue

scientific article published on 25 September 2015

The Specificity of Rabies Virus RNA Encapsidation by Nucleoprotein ⬇️

scientific article published on March 1, 1998

The development of monoclonal human rabies virus-neutralizing antibodies as a substitute for pooled human immune globulin in the prophylactic treatment of rabies virus exposure.

scientific article published in February 2000

The production of antibody by invading B cells is required for the clearance of rabies virus from the central nervous system.

scientific article

The role of immune responses in the pathogenesis of rabies.

scientific article

The role of toll-like receptors in the induction of immune responses during rabies virus infection.

scientific article published on January 2011

The therapeutic effects of PJ34 [N-(6-oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide.HCl], a selective inhibitor of poly(ADP-ribose) polymerase, in experimental allergic encephalomyelitis are associated with immunomodulation.

scientific article

Therapeutic Immune Clearance of Rabies Virus from the CNS ⬇️

scientific article published on March 1, 2011

Therapeutic intervention in experimental allergic encephalomyelitis by administration of uric acid precursors.

scientific article

Type 1 Immune Mechanisms Driven by the Response to Infection with Attenuated Rabies Virus Result in Changes in the Immune Bias of the Tumor Microenvironment and Necrosis of Mouse GL261 Brain Tumors.

scientific article published on May 2017

Uric acid, a natural scavenger of peroxynitrite, in experimental allergic encephalomyelitis and multiple sclerosis ⬇️

scientific article published on January 20, 1998

Use of Advanced Magnetic Resonance Imaging Techniques in Neuromyelitis Optica Spectrum Disorder

scientific article

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