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List of works by Nadia Rucci

A new heterozygous mutation (R714C) of the osteopetrosis gene, pleckstrin homolog domain containing family M (with run domain) member 1 (PLEKHM1), impairs vesicular acidification and increases TRACP secretion in osteoclasts

scientific article

A six-gene signature predicting breast cancer lung metastasis.

scientific article

Beta-Arrestin2 regulates RANKL and ephrins gene expression in response to bone remodeling in mice.

scientific article published on May 2009

Biotechnological approach for systemic delivery of membrane Receptor Activator of NF-κB Ligand (RANKL) active domain into the circulation.

scientific article

Characterization of the osteoblast-like cell phenotype under microgravity conditions in the NASA-approved rotating wall vessel bioreactor (RWV)

scientific article published in 2002

Clinical, genetic, and cellular analysis of 49 osteopetrotic patients: implications for diagnosis and treatment.

scientific article published on 23 August 2005

Effective Small Interfering RNA Therapy to Treat CLCN7-dependent Autosomal Dominant Osteopetrosis Type 2.

scientific article published on September 2015

Effects of blocking urokinase receptor signaling by antisense oligonucleotides in a mouse model of experimental prostate cancer bone metastases.

scientific article

Expression of platelet-derived growth factor-A (PDGF-A), PDGF-B, and PDGF receptor-alpha and -beta during human testicular development and disease

scientific article published on 01 May 2002

Fas and Fas ligand expression in fetal and adult human testis with normal or deranged spermatogenesis

scientific article published on 01 August 2000

Global transcriptome analysis in mouse calvarial osteoblasts highlights sets of genes regulated by modeled microgravity and identifies a "mechanoresponsive osteoblast gene signature".

scientific article

Imbalance of osteoclastogenesis-regulating factors in patients with celiac disease.

scientific article

In vivo bone metastases, osteoclastogenic ability, and phenotypic characterization of human breast cancer cells

scientific article published in April 2004

Increased expression of a set of genes enriched in oxygen binding function discloses a predisposition of breast cancer bone metastases to generate metastasis spread in multiple organs

scientific article

Inhibition of protein kinase c-Src as a therapeutic approach for cancer and bone metastases.

scientific article published on April 2008

Inhibition of protein kinase c-Src reduces the incidence of breast cancer metastases and increases survival in mice: implications for therapy

scientific article published on 20 April 2006

Kinase-dependent and -independent roles of EphA2 in the regulation of prostate cancer invasion and metastasis

scientific article

Lipocalin 2: a new mechanoresponding gene regulating bone homeostasis

scientific article published on 01 February 2015

Mechanisms inducing low bone density in Duchenne muscular dystrophy in mice and humans

scientific article

Modeled microgravity stimulates osteoclastogenesis and bone resorption by increasing osteoblast RANKL/OPG ratio

scientific article published on 01 February 2007

Molecular pathogenesis of bone metastases in breast cancer: Proven and emerging therapeutic targets

scientific article

Ontogenesis and cell specific localization of Fas ligand expression in the rat testis.

scientific article published in October 2004

Osteoblast and osteocyte: games without frontiers.

scientific article published on 14 May 2014

Prostate cancer and bone: the elective affinities.

scientific article

Pyrrolopyrimidine c-Src inhibitors reduce growth, adhesion, motility and invasion of prostate cancer cells in vitro.

scientific article published in September 2003

Receptor activator of NF-kappaB ligand enhances breast cancer-induced osteolytic lesions through upregulation of extracellular matrix metalloproteinase inducer/CD147.

scientific article published on 14 July 2010

Reduction of c-Src activity by substituted 5,7-diphenyl-pyrrolo[2,3-d]-pyrimidines induces osteoclast apoptosis in vivo and in vitro. Involvement of ERK1/2 pathway

scientific article published in January 2004

Regulation by thyroid hormone of the expression of basement membrane components in rat prepubertal Sertoli cells

scientific article published on 01 February 1998

Suppression of EGF-R signaling reduces the incidence of prostate cancer metastasis in nude mice

scientific article published on March 2006

The C-terminal domain of chondroadherin: a new regulator of osteoclast motility counteracting bone loss

scientific article published in August 2014

The glycosaminoglycan-binding domain of PRELP acts as a cell type-specific NF-kappaB inhibitor that impairs osteoclastogenesis

scientific article

The α2β1 binding domain of chondroadherin inhibits breast cancer-induced bone metastases and impairs primary tumour growth: a preclinical study

scientific article published on 18 December 2014

c-Src and IL-6 inhibit osteoblast differentiation and integrate IGFBP5 signalling

scientific article published in Nature Communications

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