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List of works by Kevin J Marchbank

A CD21 low phenotype, with no evidence of autoantibodies to complement proteins, is consistent with a poor prognosis in CLL

scientific article published on 3 October 2015

A De Novo Deletion in the Regulators of Complement Activation Cluster Producing a Hybrid Complement Factor H/Complement Factor H-Related 3 Gene in Atypical Hemolytic Uremic Syndrome.

scientific article

A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome

scientific article

A novel method for direct measurement of complement convertases activity in human serum.

scientific article

An Engineered Complement Factor H Construct for Treatment of C3 Glomerulopathy

scientific article published on 27 March 2018

An extended mini-complement factor H molecule ameliorates experimental C3 glomerulopathy.

scientific article published on 29 July 2015

Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome

scientific article

Autoantibodies to CD59, CD55, CD46 or CD35 are not associated with atypical haemolytic uraemic syndrome (aHUS).

scientific article

B cells from mice prematurely expressing human complement receptor type 2 are unresponsive to T-dependent antigens

scientific article published on 01 June 2005

CD19 is essential for B cell activation by promoting B cell receptor–antigen microcluster formation in response to membrane-bound ligand

scientific article published on 02 December 2007

CD59a deficient mice display reduced B cell activity and antibody production in response to T-dependent antigens.

scientific article published on 12 February 2007

Characterization of a factor H mutation that perturbs the alternative pathway of complement in a family with membranoproliferative GN.

scientific article

Characterization of the mouse analogues of CD59 using novel monoclonal antibodies: tissue distribution and functional comparison ⬇️

scientific article published on May 1, 2003

Complement: central to innate immunity and bridging to adaptive responses.

scientific article

Defective B cell ontogeny and humoral immune response in mice prematurely expressing human complement receptor 2 (CR2, CD21) is similar to that seen in aging wild type mice

scientific article published on 8 April 2009

Determining the population frequency of the CFHR3/CFHR1 deletion at 1q32.

scientific article

Editorial: Autoantibodies in Kidney Diseases

scientific article published on 16 September 2020

Expression of human complement receptor type 2 (CD21) in mice during early B cell development results in a reduction in mature B cells and hypogammaglobulinemia.

scientific article

Factor H autoantibodies in membranoproliferative glomerulonephritis.

scientific article published on 20 June 2012

Factor I autoantibodies are associated with atypical haemolytic uraemic syndrome

scholarly article by David Kavanagh et al published August 2010 in Molecular Immunology

Factor I autoantibodies in patients with atypical hemolytic uremic syndrome: disease-associated or an epiphenomenon?

scientific article

Genotype/phenotype correlations in complement factor H deficiency arising from uniparental isodisomy

scientific article

Impact of compound heterozygous complement factor H mutations on development of atypical hemolytic uremic syndrome-A pedigree revisited

scientific article

Increased B cell deletion and significantly reduced auto-antibody titre due to premature expression of human complement receptor 2 (CR2, CD21).

scientific article published on February 2009

Intrinsic B cell hypo-responsiveness in mice prematurely expressing human CR2/CD21 during B cell development

scientific article published on 01 March 2007

Large expert-curated database for benchmarking document similarity detection in biomedical literature search

scientific article published on 01 January 2019

Large-Scale Whole-Genome Sequencing Reveals the Genetic Architecture of Primary Membranoproliferative GN and C3 Glomerulopathy

scientific article published on 09 January 2020

Mechanisms of complement resistance induced by non-lethal complement attack and by growth arrest

scientific article published on 01 April 1997

Mice expressing human CR1/CD35 have an enhanced humoral immune response to T-dependent antigens but fail to correct the effect of premature human CR2 expression ⬇️

scientific article published on June 25, 2011

Modulation of the Alternative Pathway of Complement by Murine Factor H-Related Proteins

scientific article published on 29 November 2017

Molecular cloning, chromosomal localization, expression, and functional characterization of the mouse analogue of human CD59.

scientific article published on February 1997

Postpartum aHUS secondary to a genetic abnormality in factor H acquired through liver transplantation.

scientific article published on 15 March 2012

Regulation of CD59 expression on K562 cells: effects of phorbol myristate acetate, cross-linking antibody and non-lethal complement attack

scientific article published on 01 May 1995

Selectivity of C3-opsonin targeted complement inhibitors: A distinct advantage in the protection of erythrocytes from paroxysmal nocturnal hemoglobinuria patients.

scientific article published on 6 January 2016

Standardisation of the factor H autoantibody assay

scientific article

Successful renal transplantation in factor H autoantibody associated HUS with CFHR1 and 3 deficiency and CFH variant G2850T.

scientific article

The role of ADAMTS-13 activity and complement mutational analysis in differentiating acute thrombotic microangiopathies

scientific article

Thrombotic Microangiopathy in Inverted Formin 2-Mediated Renal Disease

scientific article

Triggering of atypical hemolytic uremic syndrome by influenza A (H1N1).

scientific article

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