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List of works by Michelino De Laurentiis

A Psychosocial Genomics Pilot Study in Oncology for Verifying Clinical, Inflammatory and Psychological Effects of Mind-Body Transformations-Therapy (MBT-T) in Breast Cancer Patients: Preliminary Results

scientific article published on 03 January 2021

A meta-analysis on the interaction between HER-2 expression and response to endocrine treatment in advanced breast cancer

scientific article published in July 2005

A novel neural network-based survival analysis model.

scientific article published in June 2003

A randomised factorial trial of sequential doxorubicin and CMF vs CMF and chemotherapy alone vs chemotherapy followed by goserelin plus tamoxifen as adjuvant treatment of node-positive breast cancer

scientific article published on February 2005

A technique for using neural network analysis to perform survival analysis of censored data

scientific article published on March 1994

Active lifestyles in older adults: an integrated predictive model of physical activity and exercise.

scientific article published on 22 May 2018

Adipose microenvironment promotes triple negative breast cancer cell invasiveness and dissemination by producing CCL5.

scientific article published on 24 March 2016

Adjuvant Subcutaneous Trastuzumab for HER2-Positive Early Breast Cancer: Subgroup Analyses of Safety and Active Medical Conditions by Body Weight in the SafeHer Phase III Study

scientific article published on 17 July 2018

Adjuvant anastrozole versus exemestane versus letrozole, upfront or after 2 years of tamoxifen, in endocrine-sensitive breast cancer (FATA-GIM3): a randomised, phase 3 trial.

scientific article

Adjuvant zoledronic acid and letrozole plus ovarian function suppression in premenopausal breast cancer: HOBOE phase 3 randomised trial

scientific article published on 01 June 2019

An Italian Delphi study to evaluate consensus on adjuvant endocrine therapy in premenopausal patients with breast cancer: the ERA project

article

An interaction network approach to study the correlation between endocrine disrupting chemicals and breast cancer.

scientific article

Androgen receptor in triple negative breast cancer: A potential target for the targetless subtype

scientific article published on 11 June 2018

Artificial neural network analysis of circulating tumor cells in metastatic breast cancer patients

scientific article

Bevacizumab as first-line treatment in HER2-negative advanced breast cancer: pros and cons

scientific article published on 23 August 2016

Bevacizumab plus chemotherapy versus chemotherapy alone as second-line treatment for patients with HER2-negative locally recurrent or metastatic breast cancer after first-line treatment with bevacizumab plus chemotherapy (TANIA): an open-label, rando

scientific article published on 28 September 2014

Biopsy confirmation of metastatic sites in breast cancer patients: clinical impact and future perspectives

scientific article

Body mass index and treatment outcomes following neoadjuvant therapy in women aged 45 y or younger: Evidence from a historic cohort

scientific article published on 02 March 2016

Body weight and risk of molecular breast cancer subtypes among postmenopausal Mediterranean women.

scientific article

Bone effect of adjuvant tamoxifen, letrozole or letrozole plus zoledronic acid in early-stage breast cancer: the randomized phase 3 HOBOE study

scientific article published on 12 March 2012

Buparlisib plus fulvestrant versus placebo plus fulvestrant for postmenopausal, hormone receptor-positive, human epidermal growth factor receptor 2-negative, advanced breast cancer: Overall survival results from BELLE-2.

scientific article

Buparlisib plus fulvestrant versus placebo plus fulvestrant in postmenopausal, hormone receptor-positive, HER2-negative, advanced breast cancer (BELLE-2): a randomised, double-blind, placebo-controlled, phase 3 trial.

scientific article

CDK 4/6 Inhibitors as Single Agent in Advanced Solid Tumors

scientific article published on 12 December 2018

CMF vs alternating CMF/EV in the adjuvant treatment of operable breast cancer. A single centre randomised clinical trial (Naples GUN-3 study).

scientific article

Cardiotoxicity and pro-inflammatory effects of the immune checkpoint inhibitor Pembrolizumab associated to Trastuzumab

scientific article published on 17 May 2019

Cardiovascular complications of conventional and targeted adjuvant breast cancer therapy.

scientific article

Central nervous system metastases in a cohort of metastatic breast cancer patients treated with trastuzumab

scientific article published on 01 April 2008

Chemotherapy-induced nausea and vomiting in Italian cancer centers: results of CINVDAY, a prospective, multicenter study

scientific article published on November 2014

Circulating tumor DNA analysis in breast cancer: Is it ready for prime-time?

scientific article published on 11 January 2019

Circulating tumor cells as prognostic and predictive markers in metastatic breast cancer patients receiving first-line systemic treatment

scientific article published on 15 June 2011

Circulating tumor cells in immunohistochemical subtypes of metastatic breast cancer: lack of prediction in HER2-positive disease treated with targeted therapy.

scientific article

Combination of inositol and alpha lipoic acid in metabolic syndrome-affected women: a randomized placebo-controlled trial

scientific article published on 28 August 2013

Combined effect of obesity and diabetes on early breast cancer outcome: a prospective observational study

scientific article published on 5 December 2017

Continuing trastuzumab beyond disease progression: outcomes analysis in patients with metastatic breast cancer.

scientific article published on 16 July 2008

Controversies in monitoring metastatic breast cancer during systemic treatment. Results of a GIM (Gruppo Italiano Mammella) survey

scientific article published on 19 April 2018

Corrigendum to “Gene expression profiling in breast cancer: A clinical perspective” [The Breast 22 (2013) 109–120]

article

Crosstalk between bone niche and immune system: osteoimmunology signaling as a potential target for cancer treatment

scientific article

Demographic, tumor and clinical features of clinical trials versus clinical practice patients with HER2-positive early breast cancer: results of a prospective study.

scientific article published on 25 August 2015

Dendritic cell-based vaccines: clinical applications in breast cancer.

scientific article published on January 2014

Docetaxel, Vinorelbine, and Zoledronic Acid as First-Line Treatment in Patients with Hormone Refractory Prostate Cancer: A Phase II Study

article

Dose-dense adjuvant chemotherapy in premenopausal breast cancer patients: A pooled analysis of the MIG1 and GIM2 phase III studies.

scientific article published on 9 December 2016

Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

scientific article (publication date: May 2005)

Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials

scientific article (publication date: December 2005)

Efficacy and safety of T-DM1 in the 'common-practice' of HER2+ advanced breast cancer setting: a multicenter study.

scientific article published on 18 March 2017

Electrochemotherapy in the Treatment of Cutaneous Metastases from Breast Cancer: A Multicenter Cohort Analysis

scientific article

Endocrine factors in the outcome of systemic adjuvant therapy of early breast cancer.

scientific article

Endocrine therapy in post-menopausal women with metastatic breast cancer: From literature and guidelines to clinical practice.

scientific article published on 18 February 2016

Endocrine therapy in premenopausal women with breast cancer: a critical appraisal of current evidence

scientific article

Endocrine treatment versus chemotherapy in postmenopausal women with hormone receptor-positive, HER2-negative, metastatic breast cancer: a systematic review and network meta-analysis

scientific article published on 04 September 2019

Epithelial-mesenchymal transition and stem cell markers in patients with HER2-positive metastatic breast cancer.

scientific article

Eribulin as an effective monotherapy in a chemo-pretreated woman with metastatic breast cancer: a case report.

scientific article published on April 2017

Erratum to "Chemotherapy-induced nausea and vomiting in Italian cancer centers: results of CINVDAY, a prospective, multicenter study" - Tumori. 2014 Nov-Dec;100(6):e309-13

article

Expression of proto-oncogene c-kit in high risk prostate cancer

scientific article published on 01 November 2004

Fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection plus chemotherapy in HER2-positive early breast cancer (FeDeriCa): a randomised, open-label, multicentre, non-inferiority, phase 3 study

scientific article published on 17 December 2020

Fluorouracil and dose-dense chemotherapy in adjuvant treatment of patients with early-stage breast cancer: an open-label, 2 × 2 factorial, randomised phase 3 trial

scientific article published on 2 March 2015

Gene Expression Assay in the Management of Early Breast Cancer

scientific article published on 05 December 2019

Glucose impairs tamoxifen responsiveness modulating connective tissue growth factor in breast cancer cells.

scientific article published on 20 November 2017

High Ki-67 score is indicative of a greater benefit from adjuvant chemotherapy when added to endocrine therapy in luminal B HER2 negative and node-positive breast cancer.

scientific article published on 4 December 2013

Human epidermal growth factor receptor 2 dual blockade with trastuzumab and pertuzumab in real life: Italian clinical practice versus the CLEOPATRA trial results.

scientific article published on 26 December 2017

Imaging tests in staging and surveillance of non-metastatic breast cancer: changes in routine clinical practice and cost implications

scientific article published on 07 February 2017

Incidence of nausea and vomiting in breast cancer patients treated with anthracycline plus cyclophosphamide-based chemotherapy regimens in Italy: NAVY observational study

scientific article published on 25 June 2018

Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials

article

Ipatasertib plus paclitaxel versus placebo plus paclitaxel as first-line therapy for metastatic triple-negative breast cancer (LOTUS): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial

scientific article published on 8 August 2017

Is There Still a Role for Endocrine Therapy Alone in HR+/HER2- Advanced Breast Cancer Patients? Results from the Analysis of Two Data Sets of Patients Treated with High-Dose Fulvestrant as First-Line Therapy in the Real-World Setting: The EVA and GI

scientific article published on 17 April 2019

Lapatinib in breast cancer: clinical experiences and future perspectives

scientific article

LncRNA HOTAIR up-regulation is strongly related with lymph nodes metastasis and LAR subtype of Triple Negative Breast Cancer.

scientific article

Long Non-Coding RNA HOTAIR in Breast Cancer Therapy

scientific article published on 09 May 2020

Low glycemic index diet, exercise and vitamin D to reduce breast cancer recurrence (DEDiCa): design of a clinical trial

scientific article

Metabolic and anthropometric changes in early breast cancer patients receiving adjuvant therapy.

scientific article

Metabolic syndrome-breast cancer link varies by intrinsic molecular subtype

scientific article

Molecular mechanism and clinical implications of endocrine therapy resistance in breast cancer.

scientific article published on January 2009

Molecular profiles of screen detected vs. symptomatic breast cancer and their impact on survival: results from a clinical series

scientific article

NLRP3 as Putative Marker of Ipilimumab-Induced Cardiotoxicity in the Presence of Hyperglycemia in Estrogen-Responsive and Triple-Negative Breast Cancer Cells

scientific article published on 21 October 2020

Neural network analysis for evaluating cancer risk in thyroid nodules with an indeterminate diagnosis at aspiration cytology: identification of a low-risk subgroup.

scientific article published in December 2004

Optimum chemotherapy regimen for early breast cancer

scientific article published on 01 June 2011

Pathophysiology of cardiotoxicity from target therapy and angiogenesis inhibitors.

scientific article published on May 2016

Pembrolizumab monotherapy for previously untreated, PD-L1-positive, metastatic triple-negative breast cancer: cohort B of the phase II KEYNOTE-086 study

scientific article published on 01 March 2019

Phase II study of gefitinib in combination with docetaxel as first-line therapy in metastatic breast cancer

scientific article published on June 2006

Phase II study of sorafenib in patients with sunitinib-refractory metastatic renal cell cancer

scientific article published on 3 August 2009

Phase III Randomized Study of Ribociclib and Fulvestrant in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: MONALEESA-3

scientific article published on 03 June 2018

Preclinical and phase I study of oxaliplatin and topotecan in combination in human cancer.

scientific article

Prediction of axillary lymph node status in breast cancer patients by use of prognostic indicators

scientific article published on 01 December 1994

Prognostic Value of Cancer Stem Cells Markers in Triple-Negative Breast Cancer

scientific article published on 4 October 2015

Prognostic factors: rationale and methods of analysis and integration

scientific article published on January 1994

Prognostic significance of necrosis, elastosis, fibrosis and inflammatory cell reaction in operable breast cancer

scientific article published on 01 July 1995

Programmed Death Ligand 1 (PD-L1) Tumor Expression Is Associated with a Better Prognosis and Diabetic Disease in Triple Negative Breast Cancer Patients

scientific article published on 21 February 2017

Progression-Free Survival and Overall Survival of CDK 4/6 Inhibitors Plus Endocrine Therapy in Metastatic Breast Cancer: A Systematic Review and Meta-Analysis

scientific article published on 03 September 2020

Quality of Life in Women Diagnosed with Breast Cancer after a 12-Month Treatment of Lifestyle Modifications

scientific article published on 31 December 2020

Randomised phase 3 open-label trial of first-line treatment with gemcitabine in association with docetaxel or paclitaxel in women with metastatic breast cancer: a comparison of different schedules and treatments.

scientific article

Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials

scientific article

Ribociclib plus endocrine therapy for premenopausal women with hormone-receptor-positive, advanced breast cancer (MONALEESA-7): a randomised phase 3 trial

scientific article published on 24 May 2018

Risk Differences Between Prediabetes And Diabetes According To Breast Cancer Molecular Subtypes.

scientific article published on 31 August 2016

Second-line chemotherapy with a hybrid-alternating regimen of bolus 5FU modulated by methotrexate and infusional 5FU modulated by folinic acid in patients with metastatic colorectal cancer pretreated with 5FU. A phase 2 study

scientific article published in January 2002

Self-Efficacy for Coping with Cancer Enhances the Effect of Reiki Treatments During the Pre-Surgery Phase of Breast Cancer Patients.

scientific article published in July 2017

Self-efficacy for Coping Moderates the Effects of Distress on Quality of Life in Palliative Cancer Care.

scientific article published in April 2017

Surgery of the primary tumor in de novo metastatic breast cancer: To do or not to do?

scientific article published on 29 July 2015

Survival analysis of censored data: neural network analysis detection of complex interactions between variables

scientific article published on January 1994

Targeting Autophagy in Breast Cancer

scientific article published on 22 October 2020

Targeting Cell Cycle in Breast Cancer: CDK4/6 Inhibitors

scientific article published on 04 September 2020

Targeting HER2 as a therapeutic strategy for breast cancer: a paradigmatic shift of drug development in oncology.

scientific article

Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials

scientific article published in January 2008

The Elapsed Time During a Virtual Reality Treatment for Stressful Procedures. A Pool Analysis on Breast Cancer Patients During Chemotherapy

The MAGIC survey in hormone receptor positive (HR+), HER2-negative (HER2-) breast cancer: When might multigene assays be of value?

scientific article

The role of taxanes in triple-negative breast cancer: literature review

scientific article (publication date: 2015)

Topotecan compared with no therapy after response to surgery and carboplatin/paclitaxel in patients with ovarian cancer: Multicenter Italian Trials in Ovarian Cancer (MITO-1) randomized study

scientific article

Treatment of triple negative breast cancer (TNBC): current options and future perspectives

scientific article

Unexpected ovarian activity in premenopausal breast cancer survivors treated with exemestane and GnRH analogues

scientific article published on 23 July 2019

Virtual Reality in Health System: Beyond Entertainment. A Mini-Review on the Efficacy of VR During Cancer Treatment.

scientific article published on 03 August 2015

Weekly docetaxel versus CMF as adjuvant chemotherapy for older women with early breast cancer: final results of the randomized phase III ELDA trial.

scientific article published on 8 December 2014

c-erbB2 expression predicts tamoxifen efficacy in breast cancer patients

scientific article