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List of works by Malcolm Whiteway

A biochemical genomics screen for substrates of Ste20p kinase enables the in silico prediction of novel substrates

scientific article

A functional portrait of Med7 and the mediator complex in Candida albicans

scientific article

A human-curated annotation of the Candida albicans genome

scientific article

A novel role for the transcription factor Cwt1p as a negative regulator of nitrosative stress in Candida albicans

scientific article

A toolbox for epitope-tagging and genome-wide location analysis in Candida albicans

scientific article

Adaptations of Candida albicans for growth in the mammalian intestinal tract

scientific article

Adaptor protein Ste50p links the Ste11p MEKK to the HOG pathway through plasma membrane association.

scientific article

Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes.

scientific article

Barrier activity in Candida albicans mediates pheromone degradation and promotes mating

scientific article

Beauvericin Potentiates Azole Activity via Inhibition of Multidrug Efflux, Blocks Candida albicans Morphogenesis, and Is Effluxed via Yor1 and Circuitry Controlled by Zcf29.

scientific article published on 10 October 2016

Binding the atypical RA domain of Ste50p to the unfolded Opy2p cytoplasmic tail is essential for the high-osmolarity glycerol pathway.

scientific article published on December 2009

CDC42 is required for polarized growth in human pathogen Candida albicans.

scientific article

Candida morphogenesis and host-pathogen interactions

scientific article published in August 2004

Cell cycle arrest during S or M phase generates polarized growth via distinct signals in Candida albicans

scientific article published in August 2005

Chemogenomic profiling of the fungal pathogen Candida albicans

scientific article

Chemogenomic profiling predicts antifungal synergies.

scientific article

Cinnamomum zeylanicum bark essential oil induces cell wall remodelling and spindle defects in Candida albicans

scientific article published on 9 February 2018

Clathrin- and Arp2/3-independent endocytosis in the fungal pathogen Candida albicans

scientific article published on 27 August 2013

Cold adaptation in budding yeast

scientific article

Comparative xylose metabolism among the Ascomycetes C. albicans, S. stipitis and S. cerevisiae

scientific article (publication date: 2013)

Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae.

scientific article published on October 2002

Cyclin Cln3p links G1 progression to hyphal and pseudohyphal development in Candida albicans

scientific article

Deletion of a Yci1 Domain Protein of Candida albicans Allows Homothallic Mating in MTL Heterozygous Cells.

scientific article published on 26 April 2016

Depletion of a polo-like kinase in Candida albicans activates cyclase-dependent hyphal-like growth

scientific article

Disruption of a gene encoding glycerol 3-phosphatase from Candida albicans impairs intracellular glycerol accumulation-mediated salt-tolerance

scientific article published in April 2005

Drag&Drop cloning in yeast

scientific article

Drosophila innate immunity and response to fungal infections

scientific article published on 30 January 2008

Epigenetic control of pheromone MAPK signaling determines sexual fecundity in Candida albicans.

scientific article published on 18 December 2017

Erratum for Chen et al., "Chemogenomic Profiling of the Fungal Pathogen Candida albicans".

scientific article published on 27 March 2018

Evolutionary Transition of GAL Regulatory Circuit from Generalist to Specialist Function in Ascomycetes

scientific article published on 25 January 2018

Evolutionary reshaping of fungal mating pathway scaffold proteins

scientific article

Evolutionary tinkering with conserved components of a transcriptional regulatory network

scientific article

Experimental annotation of the human pathogen Candida albicans coding and noncoding transcribed regions using high-resolution tiling arrays

scientific article

Expression of CaPTC7 is developmentally regulated during serum-induced morphogenesis in the human fungal pathogen Candida albicans

scientific article published in February 2007

Forward genetics in Candida albicans that reveals the Arp2/3 complex is required for hyphal formation, but not endocytosis.

scientific article

Functional characterization of myosin I tail regions in Candida albicans

scientific article

Functional dissection of human protease mu-calpain in cell migration using RNAi

scientific article published on 06 May 2006

Functional divergence of a global regulatory complex governing fungal filamentation

scientific article published on 07 January 2019

Gene expression in HL60 granulocytoids and human polymorphonuclear leukocytes exposed to Candida albicans

scientific article

Generation of conditional lethal Candida albicans mutants by inducible deletion of essential genes

article

Genetic analysis of the interface between Cdc42p and the CRIB domain of Ste20p in Saccharomyces cerevisiae

scientific article

Genome-wide mapping of the coactivator Ada2p yields insight into the functional roles of SAGA/ADA complex in Candida albicans

scientific article published on 11 March 2009

Global gene deletion analysis exploring yeast filamentous growth

scientific article published on 01 September 2012

Grb10 and active Raf-1 kinase promote Bad-dependent cell survival

scientific article published on 29 May 2007

Heterotrimeric G-protein subunit function in Candida albicans: both the alpha and beta subunits of the pheromone response G protein are required for mating

scientific article published on 25 July 2008

High-affinity transporters for NAD+ precursors in Candida glabrata are regulated by Hst1 and induced in response to niacin limitation

scientific article published on 18 May 2009

Hof1 plays a checkpoint-related role in MMS-induced DNA damage response in Candida albicans

scientific article published on 15 January 2020

Identification and characterization of MFA1, the gene encoding Candida albicans a-factor pheromone

scientific article published on 5 January 2007

Immune-deficient Drosophila melanogaster: a model for the innate immune response to human fungal pathogens.

scientific article published in May 2004

In vivo and in vitro anaerobic mating in Candida albicans

scientific article published on 26 January 2007

Increased respiration in the sch9Delta mutant is required for increasing chronological life span but not replicative life span

scientific article published on 9 May 2008

Loss of RPS41 but not its paralog RPS42 results in altered growth, filamentation and transcriptome changes in Candida albicans

scientific article published on 29 April 2015

MAP Kinase Regulation of the Pheromone Pathway

article by Golnaz Rastghalam et al published 20 February 2019 in mSphere

MFalpha1, the gene encoding the alpha mating pheromone of Candida albicans

scientific article

Metabolic regulation in model ascomycetes--adjusting similar genomes to different lifestyles.

scientific article published on 05 June 2015

Mms21: A Putative SUMO E3 Ligase in Candida albicans That Negatively Regulates Invasiveness and Filamentation, and Is Required for the Genotoxic and Cellular Stress Response

scientific article published on 07 December 2018

Modeling the transcriptional regulatory network that controls the early hypoxic response in Candida albicans

scientific article

Morphogenesis in Candida albicans

scientific article published on January 2007

Motor Protein Myo5p Is Required To Maintain the Regulatory Circuit Controlling WOR1 Expression in Candida albicans

scientific article published on March 9, 2012

Msn2- and Msn4-like transcription factors play no obvious roles in the stress responses of the fungal pathogen Candida albicans.

scientific article published on October 2004

Negative regulation of MAPKK by phosphorylation of a conserved serine residue equivalent to Ser212 of MEK1.

scientific article published on 27 December 2002

Negative regulation of filamentous growth in Candida albicans by Dig1p

scientific article

Normal Adaptation of Candida albicans to the Murine Gastrointestinal Tract Requires Efg1p-Dependent Regulation of Metabolic and Host Defense Genes

scientific article published on November 2, 2012

Nucleotide Excision Repair Protein Rad23 Regulates Cell Virulence Independent of Rad4 in Candida albicans

scientific article published on 19 February 2020

PalI domain proteins of Saccharomyces cerevisiae and Candida albicans

scientific article published on February 29, 2012

Pho85, Pcl1, and Hms1 signaling governs Candida albicans morphogenesis induced by high temperature or Hsp90 compromise.

scientific article published on 23 February 2012

Phosphorylation of the MAPKKK regulator Ste50p in Saccharomyces cerevisiae: a casein kinase I phosphorylation site is required for proper mating function

scientific article

Proteomic analysis of Candida albicans yeast and hyphal cell wall and associated proteins

scientific article published on 01 April 2006

Put3 Positively Regulates Proline Utilization in Candida albicans.

scientific article published in November 2017

RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans

scientific article published on 03 January 2020

Rearrangements of the transcriptional regulatory networks of metabolic pathways in fungi

scientific article published on 29 October 2009

Recent advances on Candida albicans biology and virulence

scientific article

Release from quorum-sensing molecules triggers hyphal formation during Candida albicans resumption of growth

scientific article

Reverse genetics in Candida albicans predicts ARF cycling is essential for drug resistance and virulence

scientific article

Rewiring of the Ppr1 Zinc Cluster Transcription Factor from Purine Catabolism to Pyrimidine Biogenesis in the Saccharomycetaceae

scientific article published on 15 June 2016

Rho5p is involved in mediating the osmotic stress response in Saccharomyces cerevisiae, and its activity is regulated via Msi1p and Npr1p by phosphorylation and ubiquitination

scientific article published on 11 July 2008

Role of transcription factor CaNdt80p in cell separation, hyphal growth, and virulence in Candida albicans

scientific article

SRYTH: A New Yeast Two-Hybrid Method

scientific article published on 01 January 2016

SST2, a regulator of G-protein signaling for the Candida albicans mating response pathway

scientific article

Screening of Candida albicans GRACE library revealed a unique pattern of biofilm formation under repression of the essential gene ILS1

scientific article published on 24 June 2019

Self-regulation of Candida albicans population size during GI colonization

scientific article

Solution structure of the dimeric SAM domain of MAPKKK Ste11 and its interactions with the adaptor protein Ste50 from the budding yeast: implications for Ste11 activation and signal transmission through the Ste50-Ste11 complex

scientific article published on 01 December 2004

Ste18p is a positive control element in the mating process of Candida albicans

scientific article

Stress-induced gene expression in Candida albicans: absence of a general stress response.

scientific article

Structurally unique interaction of RBD-like and PH domains is crucial for yeast pheromone signaling

scientific article published on December 14, 2012

Superoxide Dismutases inCandida albicans: Transcriptional Regulation and Functional Characterization of the Hyphal-inducedSOD5Gene

scientific article published on November 14, 2003

The Evolutionary Rewiring of the Ribosomal Protein Transcription Pathway Modifies the Interaction of Transcription Factor Heteromer Ifh1-Fhl1 (Interacts with Forkhead 1-Forkhead-like 1) with the DNA-binding Specificity Element

scientific article published on April 26, 2013

The Genomic Landscape of the Fungus-Specific SWI/SNF Complex Subunit, Snf6, in Candida albicans.

scientific article published on 15 November 2017

The MyLO CRISPR-Cas9 toolkit: a markerless yeast localization and overexpression CRISPR-Cas9 toolkit

scientific article published in 2022

The Role of Mms22p in DNA Damage Response in Candida albicans.

scientific article

The YHR076w gene encodes a type 2C protein phosphatase and represents the seventh PP2C gene in budding yeast

scientific article

The adaptor protein Ste50 directly modulates yeast MAPK signaling specificity through differential connections of its RA domain

scientific article published on 16 January 2019

The plasma membrane protein Rch1 is a negative regulator of cytosolic calcium homeostasis and positively regulated by the calcium/calcineurin signaling pathway in budding yeast.

scientific article

The role of Candida albicans FAR1 in regulation of pheromone-mediated mating, gene expression and cell cycle arrest

scientific article published on 14 March 2008

The serine/threonine protein phosphatase SIT4 modulates yeast-to-hypha morphogenesis and virulence in Candida albicans

scientific article

The tricarboxylic acid cycle, cell wall integrity pathway, cytokinesis and intracellular pH homeostasis are involved in the sensitivity of Candida albicans cells to high levels of extracellular calcium

scientific article published on 10 August 2018

The zinc cluster transcription factor Ahr1p directs Mcm1p regulation of Candida albicans adhesion

scientific article

Transcript profiles of Candida albicans cortical actin patch mutants reflect their cellular defects: contribution of the Hog1p and Mkc1p signaling pathways

scientific article

Transcript profiling of a MAP kinase pathway in C. albicans

scientific article published on 08 May 2008

Transcription factor substitution during the evolution of fungal ribosome regulation

scientific article published on March 2008

Transcription profiling of Candida albicans cells undergoing the yeast-to-hyphal transition

scientific article

Transcription profiling of cyclic AMP signaling in Candida albicans.

scientific article published on 21 July 2004

Transcriptional activation domains of the Candida albicans Gcn4p and Gal4p homologs

scientific article published on 8 December 2006

Transcriptional analysis of the Candida albicans cell cycle

scientific article published on 28 May 2009

Transcriptional regulation of carbohydrate metabolism in the human pathogen Candida albicans

scientific article

Transcriptional rewiring of fungal galactose-metabolism circuitry

scientific article published on 31 May 2007

Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space.

scientific article published on 28 March 2018

Use of Dominant Negative Mutations in Analysis of G Protein Function in Saccharomyces cerevisiae

scientific article published on 01 January 2002

Virulence ofCandida albicansmutants toward larvalGalleria mellonella(Insecta, Lepidoptera, Galleridae)

scientific article published on August 1, 2003

Widespread occurrence of chromosomal aneuploidy following the routine production of Candida albicans mutants.

scientific article published on 06 August 2009

Yeast Mating: Trying Out New Pickup Lines

scientific article published on August 23, 2011

Yeast mating: putting some fizz into fungal sex?

scientific article