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List of works by Simon Alberti

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.

scientific article

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins

scientific article published on 28 June 2018

A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism.

scientific article published on 25 August 2016

A User's Guide for Phase Separation Assays with Purified Proteins

scientific article published on 23 June 2018

A complete mass-spectrometric map of the yeast proteome applied to quantitative trait analysis

scientific article

A pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy.

scientific article published on 22 March 2016

A systematic survey identifies prions and illuminates sequence features of prionogenic proteins

scientific article

ALS and FTD: Where RNA metabolism meets protein quality control

scientific article published on 01 July 2019

ATP as a biological hydrotrope.

scientific article published in May 2017

Aberrant Compartment Formation by HSPB2 Mislocalizes Lamin A and Compromises Nuclear Integrity and Function.

scientific article published on August 2017

Aggregating the message to control the cell cycle.

scientific article published in June 2013

Amyloid-like Self-Assembly of a Cellular Compartment

scientific article published on July 2016

An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function

scientific article published on 4 April 2017

Are aberrant phase transitions a driver of cellular aging?

scientific article (publication date: October 2016)

Biochemical, Cell Biological, and Genetic Assays to Analyze Amyloid and Prion Aggregation in Yeast

scientific article published on 01 March 2010

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

scientific article published on 01 January 2019

Defective ribosomal products challenge nuclear function by impairing nuclear condensate dynamics and immobilizing ubiquitin

scientific article published on 04 July 2019

Dictyostelium discoideum has a highly Q/N-rich proteome and shows an unusual resilience to protein aggregation.

scientific article published on 4 May 2015

Different Material States of Pub1 Condensates Define Distinct Modes of Stress Adaptation and Recovery

scientific article published on 01 June 2018

Don't Go with the Cytoplasmic Flow.

scientific article published in August 2015

ERα condensates: chronic stimulation is hard to ignore

scientific article published on 01 March 2019

FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy

scientific article published on 01 April 2019

Features of the Chaperone Cellular Network Revealed through Systematic Interaction Mapping

scientific article

Filament formation by the translation factor eIF2B regulates protein synthesis in starved cells

scientific article published on 17 June 2020

Gel or Die: Phase Separation as a Survival Strategy.

scientific article published in March 2017

Granulostasis: Protein Quality Control of RNP Granules ⬇️

scientific article

Guilty by Association: Mapping Out the Molecular Sociology of Droplet Compartments.

scientific article published in February 2018

HSP70-binding protein HSPBP1 regulates chaperone expression at a posttranslational level and is essential for spermatogenesis.

scientific article

Harnessing the power of yeast to unravel the molecular basis of neurodegeneration.

scientific article published on 08 May 2013

Hsp90-mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling

scientific article published on 19 March 2021

Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy

scientific article

Liquid-Liquid Phase Separation in Disease

scientific article published on 20 August 2019

Molecular chaperones and stress-inducible protein-sorting factors coordinate the spatiotemporal distribution of protein aggregates ⬇️

scientific article published on June 20, 2012

Molecular mechanisms of spatial protein quality control ⬇️

scientific article published on October 10, 2012

Non-invasive perturbations of intracellular flow reveal physical principles of cell organization.

scientific article

Nucleoli and Promyelocytic Leukemia Protein (PML) bodies are phase separated nuclear protein quality control compartments for misfolded proteins

scientific article published on 26 August 2019

Nucleolus: A Liquid Droplet Compartment for Misbehaving Proteins

scientific article published on 01 October 2019

One domain fits all: Using disordered regions to sequester misfolded proteins.

scientific article published on 9 March 2018

Opposing Effects of Glutamine and Asparagine Govern Prion Formation by Intrinsically Disordered Proteins ⬇️

scientific article published on July 8, 2011

Phase changes in neurotransmission

scientific article published on 01 August 2018

Phase separation in biology.

scientific article published in October 2017

Phase separation of a yeast prion protein promotes cellular fitness.

scientific article published in January 2018

Prion formation by a yeast GLFG nucleoporin.

scientific article

Prion-like low-complexity sequences: Key regulators of protein solubility and phase behavior

scientific article published on 19 June 2018

Protein Phase Separation: A New Phase in Cell Biology

scientific article published on 27 March 2018

Protein disorder, prion propensities, and self-organizing macromolecular collectives.

scientific article published on 14 January 2013

Protein misfolding in Dictyostelium: Using a freak of nature to gain insight into a universal problem.

scientific article published on 3 November 2015

Protein phase separation and its role in tumorigenesis

scientific article published on 03 November 2020

Proteome-wide signatures of function in highly diverged intrinsically disordered regions

scientific article published on 2 July 2019

Quality Control of Membraneless Organelles

scientific article published on 11 May 2018

RNA buffers the phase separation behavior of prion-like RNA binding proteins.

scientific article published on 12 April 2018

Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions

scientific article published on 17 February 2021

Small heat shock proteins: multifaceted proteins with important implications for life

scientific article published on 13 February 2019

Studying the Protein Quality Control System of D. discoideum Using Temperature-controlled Live Cell Imaging

scientific article

The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo

scientific article published on 13 June 2019

The wisdom of crowds: regulating cell function through condensed states of living matter.

scientific article published on 14 August 2017

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