List of works - Alessandra Bearz

ASCEND-8: A Randomized Phase 1 Study of Ceritinib, 450 mg or 600 mg, Taken with a Low-Fat Meal versus 750 mg in Fasted State in Patients with Anaplastic Lymphoma Kinase (ALK)-Rearranged Metastatic Non-Small Cell Lung Cancer (NSCLC).

scientific article published on 17 July 2017

Acquired BRAF V600E Mutation as Resistant Mechanism after Treatment with Third-Generation EGFR Tyrosine Kinase Inhibitor.

scientific article published in November 2017

Activity of crizotinib over choroidal metastases in non-small-cell lung cancer (NSCLC)-ALK rearranged: a case report.

scientific article

Adding gemcitabine to paclitaxel/carboplatin combination increases survival in advanced non-small-cell lung cancer: results of a phase II-III study

scientific article

Alectinib in Crizotinib-Refractory ALK-Rearranged Non-Small-Cell Lung Cancer: A Phase II Global Study.

scientific article

An expanded access program of erlotinib (Tarceva) in patients with advanced non-small cell lung cancer (NSCLC): data report from Italy

scientific article

BE-POSITIVE: Beyond progression after tyrosine kinase inhibitor in EGFR- positive non small cell lung cancer patients: Results from a multicenter Italian observational study.

scientific article published on 26 February 2016

Bevacizumab plus irinotecan-, fluorouracil-, and leucovorin-based chemotherapy with concomitant HAART in an HIV-positive patient with metastatic colorectal cancer.

scientific article published on 16 June 2008

Cancer in the elderly: The caregivers’ perception of senior patients’ informational needs

scientific article published on 13 December 2008

Ceritinib compassionate use for patients with crizotinib-refractory, anaplastic lymphoma kinase-positive advanced non-small-cell lung cancer

scientific article

Ceritinib versus chemotherapy in patients with ALK-rearranged non-small-cell lung cancer previously given chemotherapy and crizotinib (ASCEND-5): a randomised, controlled, open-label, phase 3 trial

scientific article published on 8 June 2017

Clinical Effectiveness and Cost-Effectiveness of Target Therapies for Adult Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer: A Systematic Review

scientific article published on 6 February 2017

Clinical presentation and outcome of colorectal cancer in HIV-positive patients: a clinical case-control study

scientific article published on 14 May 2009

Clinical significance and treatment of skin rash from erlotinib in non-small cell lung cancer patients: results of an Experts Panel Meeting.

scientific article

Comment on 'Lung cancer in the Swiss HIV Cohort Study: role of smoking, immunodeficiency and pulmonary infection'.

scientific article published on 3 May 2012

Concurrent chemoradiotherapy with tomotherapy in locally advanced Non-Small Cell Lung Cancer: a phase I, docetaxel dose-escalation study, with hypofractionated radiation regimen

scientific article

Dose finding of ifosfamide administered with a chronic two-week continuous infusion.

scientific article published in January 2003

Dose-finding/phase II trial: bevacizumab, immunotherapy, and chemotherapy (BIC) in metastatic renal cell cancer (mRCC). Antitumor effects and variations of circulating T regulatory cells (Treg).

scientific article

Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial

scientific article

FOLFOX-4 regimen with concomitant highly active antiretroviral therapy in metastatic colorectal cancer HIV-infected patients: a report of five cases and review of the literature.

scientific article published on July 2008

FOLFOX2 regimen in the treatment of advanced colorectal cancer: a comparison between elderly and young patients

scientific article published on 25 May 2006

Fatigue in cancer patients receiving chemotherapy: an analysis of published studies

scientific article published on 01 October 2004

Gefitinib in the treatment of elderly patients with advanced non-small cell lung cancer (NSCLC)

scientific article published on 24 October 2006

Immune checkpoint inhibitors and response analysis: a tough challenge. A case report

scientific article

Interleukin-2 continuous infusion and angiogenesis surrogate markers in metastatic renal cell carcinoma

scientific article published on 28 March 2006

Malignant peritoneal mesothelioma: a multicenter study on 81 cases.

scientific article published on 27 July 2009

Market and patient access to new oncology products in Europe: a current, multidisciplinary perspective

scientific article published on 01 August 2009

NGR-hTNF in combination with best investigator choice in previously treated malignant pleural mesothelioma (NGR015): a randomised, double-blind, placebo-controlled phase 3 trial

scientific article published on 09 May 2018

Neoplastic pericardial disease in lung cancer: Impact on outcomes of different treatment strategies. A multicenter study

scientific article published on 30 November 2010

Outcomes of ALK positive lung cancer patients treated with crizotinib or second-generation ALK inhibitor: a monoinstitutional experience.

scientific article published on 26 February 2018

Outcomes of First-Generation EGFR-TKIs Against Non-Small-Cell Lung Cancer Harboring Uncommon EGFR Mutations: A Post Hoc Analysis of the BE-POSITIVE Study

scientific article

Oxaliplapin and capecitabine (XELOX) based chemotherapy in the treatment of metastatic colorectal cancer: the right choice in elderly patients.

scientific article published in November 2013

Oxaliplatin and capecitabine (Xelox) in association with highly active antiretroviral therapy in advanced hepatocarcinoma HIV/HCV-infected patients

article

Oxaliplatin-based chemotherapy in the treatment of elderly patients with metastatic colorectal cancer (CRC)

scientific article published on 19 September 2011

Patient-Centered Cancer Care Programs in Italy: Benchmarking Global Patient Education Initiatives

scientific article published on 15 March 2015

Pemetrexed plus carboplatin in elderly patients with malignant pleural mesothelioma: combined analysis of two phase II trials.

scientific article

Pemetrexed single agent chemotherapy in previously treated patients with locally advanced or metastatic non-small cell lung cancer

scientific article

Pemetrexed single agent in previously treated non-small cell lung cancer: a multi-institutional observational study.

scientific article published on 26 November 2007

Phase II study of pemetrexed plus carboplatin in malignant pleural mesothelioma

scientific article published on 01 March 2006

Phase II, double-blinded, randomized study of enzastaurin plus pemetrexed as second-line therapy in patients with advanced non-small cell lung cancer

scientific article

Predictive value of a proteomic signature in patients with non-small-cell lung cancer treated with second-line erlotinib or chemotherapy (PROSE): a biomarker-stratified, randomised phase 3 trial.

scientific article published on 13 May 2014

Pretreatment quality of life and functional status assessment significantly predict survival of elderly patients with advanced non-small-cell lung cancer receiving chemotherapy: a prognostic analysis of the multicenter Italian lung cancer in the eld

scientific article

Radical Radiation Therapy After Lung-Sparing Surgery for Malignant Pleural Mesothelioma: Survival, Pattern of Failure, and Prognostic Factors.

scientific article published on 20 June 2015

Radical pleurectomy/decortication followed by high dose of radiation therapy for malignant pleural mesothelioma. Final results with long-term follow-up

scientific article published on 27 October 2013

Re-challenge with pemetrexed in advanced mesothelioma: a multi-institutional experience.

scientific article

Recent improvement in the survival of patients with advanced nonsmall cell lung cancer enrolled in phase III trials of first-line, systemic chemotherapy

scientific article published on 01 December 2007

Sequential use of sorafenib and sunitinib in advanced renal-cell carcinoma (RCC): an Italian multicentre retrospective analysis of 189 patient cases

article

Small cell lung cancer in an elderly patient: efficacy of somatostatin analog treatment, a case report

scientific article published on 18 February 2011

Solid pseudopapillary tumour of the pancreas

scientific article published on 01 April 2003

Sorafenib dose escalation in treatment-naïve patients with metastatic renal cell carcinoma: a non-randomised, open-label, Phase 2b study

scientific article published on 15 December 2016

Sorafenib for the treatment of unresectable hepatocellular carcinoma in HIV-positive patients

article

Staphylococcus cohnii septicaemia in a patient with colon cancer.

scientific article

Stereotactic body radiation therapy for re-irradiation of persistent or recurrent non-small cell lung cancer

scientific article published on 01 April 2014

Target therapies in lung cancer

scientific article

Tomotherapy after pleurectomy/decortication or biopsy for malignant pleural mesothelioma allows the delivery of high dose of radiation in patients with intact lung.

scientific article

Treatment of elderly patients affected by lung cancer: why to treat, when to treat and what we know.

scientific article

Tremelimumab as second-line or third-line treatment in relapsed malignant mesothelioma (DETERMINE): a multicentre, international, randomised, double-blind, placebo-controlled phase 2b trial.

scientific article published on 17 July 2017

List of works by Alessandra Bearz

ASCEND-8: A Randomized Phase 1 Study of Ceritinib, 450 mg or 600 mg, Taken with a Low-Fat Meal versus 750 mg in Fasted State in Patients with Anaplastic Lymphoma Kinase (ALK)-Rearranged Metastatic Non-Small Cell Lung Cancer (NSCLC).

Acquired BRAF V600E Mutation as Resistant Mechanism after Treatment with Third-Generation EGFR Tyrosine Kinase Inhibitor.

Activity of crizotinib over choroidal metastases in non-small-cell lung cancer (NSCLC)-ALK rearranged: a case report.

Adding gemcitabine to paclitaxel/carboplatin combination increases survival in advanced non-small-cell lung cancer: results of a phase II-III study

Alectinib in Crizotinib-Refractory ALK-Rearranged Non-Small-Cell Lung Cancer: A Phase II Global Study.

An expanded access program of erlotinib (Tarceva) in patients with advanced non-small cell lung cancer (NSCLC): data report from Italy

BE-POSITIVE: Beyond progression after tyrosine kinase inhibitor in EGFR- positive non small cell lung cancer patients: Results from a multicenter Italian observational study.

Bevacizumab plus irinotecan-, fluorouracil-, and leucovorin-based chemotherapy with concomitant HAART in an HIV-positive patient with metastatic colorectal cancer.

Cancer in the elderly: The caregivers’ perception of senior patients’ informational needs

Ceritinib compassionate use for patients with crizotinib-refractory, anaplastic lymphoma kinase-positive advanced non-small-cell lung cancer

Ceritinib versus chemotherapy in patients with ALK-rearranged non-small-cell lung cancer previously given chemotherapy and crizotinib (ASCEND-5): a randomised, controlled, open-label, phase 3 trial

Clinical Effectiveness and Cost-Effectiveness of Target Therapies for Adult Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer: A Systematic Review

Clinical presentation and outcome of colorectal cancer in HIV-positive patients: a clinical case-control study

Clinical significance and treatment of skin rash from erlotinib in non-small cell lung cancer patients: results of an Experts Panel Meeting.

Comment on 'Lung cancer in the Swiss HIV Cohort Study: role of smoking, immunodeficiency and pulmonary infection'.

Concurrent chemoradiotherapy with tomotherapy in locally advanced Non-Small Cell Lung Cancer: a phase I, docetaxel dose-escalation study, with hypofractionated radiation regimen

Dose finding of ifosfamide administered with a chronic two-week continuous infusion.

Dose-finding/phase II trial: bevacizumab, immunotherapy, and chemotherapy (BIC) in metastatic renal cell cancer (mRCC). Antitumor effects and variations of circulating T regulatory cells (Treg).

Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial

FOLFOX-4 regimen with concomitant highly active antiretroviral therapy in metastatic colorectal cancer HIV-infected patients: a report of five cases and review of the literature.

FOLFOX2 regimen in the treatment of advanced colorectal cancer: a comparison between elderly and young patients

Fatigue in cancer patients receiving chemotherapy: an analysis of published studies

Gefitinib in the treatment of elderly patients with advanced non-small cell lung cancer (NSCLC)

Immune checkpoint inhibitors and response analysis: a tough challenge. A case report

Interleukin-2 continuous infusion and angiogenesis surrogate markers in metastatic renal cell carcinoma

Malignant peritoneal mesothelioma: a multicenter study on 81 cases.

Market and patient access to new oncology products in Europe: a current, multidisciplinary perspective

NGR-hTNF in combination with best investigator choice in previously treated malignant pleural mesothelioma (NGR015): a randomised, double-blind, placebo-controlled phase 3 trial

Neoplastic pericardial disease in lung cancer: Impact on outcomes of different treatment strategies. A multicenter study

Outcomes of ALK positive lung cancer patients treated with crizotinib or second-generation ALK inhibitor: a monoinstitutional experience.

Outcomes of First-Generation EGFR-TKIs Against Non-Small-Cell Lung Cancer Harboring Uncommon EGFR Mutations: A Post Hoc Analysis of the BE-POSITIVE Study

Oxaliplapin and capecitabine (XELOX) based chemotherapy in the treatment of metastatic colorectal cancer: the right choice in elderly patients.

Oxaliplatin and capecitabine (Xelox) in association with highly active antiretroviral therapy in advanced hepatocarcinoma HIV/HCV-infected patients

Oxaliplatin-based chemotherapy in the treatment of elderly patients with metastatic colorectal cancer (CRC)

Patient-Centered Cancer Care Programs in Italy: Benchmarking Global Patient Education Initiatives

Pemetrexed plus carboplatin in elderly patients with malignant pleural mesothelioma: combined analysis of two phase II trials.

Pemetrexed single agent chemotherapy in previously treated patients with locally advanced or metastatic non-small cell lung cancer

Pemetrexed single agent in previously treated non-small cell lung cancer: a multi-institutional observational study.

Phase II study of pemetrexed plus carboplatin in malignant pleural mesothelioma

Phase II, double-blinded, randomized study of enzastaurin plus pemetrexed as second-line therapy in patients with advanced non-small cell lung cancer

Predictive value of a proteomic signature in patients with non-small-cell lung cancer treated with second-line erlotinib or chemotherapy (PROSE): a biomarker-stratified, randomised phase 3 trial.

Pretreatment quality of life and functional status assessment significantly predict survival of elderly patients with advanced non-small-cell lung cancer receiving chemotherapy: a prognostic analysis of the multicenter Italian lung cancer in the eld

Radical Radiation Therapy After Lung-Sparing Surgery for Malignant Pleural Mesothelioma: Survival, Pattern of Failure, and Prognostic Factors.

Radical pleurectomy/decortication followed by high dose of radiation therapy for malignant pleural mesothelioma. Final results with long-term follow-up

Re-challenge with pemetrexed in advanced mesothelioma: a multi-institutional experience.

Recent improvement in the survival of patients with advanced nonsmall cell lung cancer enrolled in phase III trials of first-line, systemic chemotherapy

Sequential use of sorafenib and sunitinib in advanced renal-cell carcinoma (RCC): an Italian multicentre retrospective analysis of 189 patient cases

Small cell lung cancer in an elderly patient: efficacy of somatostatin analog treatment, a case report

Solid pseudopapillary tumour of the pancreas

Sorafenib dose escalation in treatment-naïve patients with metastatic renal cell carcinoma: a non-randomised, open-label, Phase 2b study

Sorafenib for the treatment of unresectable hepatocellular carcinoma in HIV-positive patients

Staphylococcus cohnii septicaemia in a patient with colon cancer.

Stereotactic body radiation therapy for re-irradiation of persistent or recurrent non-small cell lung cancer

Target therapies in lung cancer

Tomotherapy after pleurectomy/decortication or biopsy for malignant pleural mesothelioma allows the delivery of high dose of radiation in patients with intact lung.

Treatment of elderly patients affected by lung cancer: why to treat, when to treat and what we know.

Tremelimumab as second-line or third-line treatment in relapsed malignant mesothelioma (DETERMINE): a multicentre, international, randomised, double-blind, placebo-controlled phase 2b trial.