List of works - Mirko Rivara

2,4(5)-Diarylimidazoles: synthesis and biological evaluation of a new class of sodium channel blockers against hNa(v)1.2.

scientific article published on 11 September 2008

2,4(5)-diarylimidazoles as inhibitors of hNaV1.2 sodium channels: pharmacological evaluation and structure-property relationships.

scientific article published on 10 April 2009

5-Benzylidene-hydantoins: synthesis and antiproliferative activity on A549 lung cancer cell line

scientific article

Anticonvulsant activity of 2,4(1H)-diarylimidazoles in mice and rats acute seizure models ⬇️

scientific article published on September 22, 2010

Chiral NMR discrimination of the diastereoisomeric salts of the H3-antagonist 2-[3-(1H-imidazol-4-ylmethyl)piperidin-1-yl]-1H-benzimidazole.

scientific article published in June 2009

Discovery of antitubercular 2,4-diphenyl-1H-imidazoles from chemical library repositioning and rational design

scientific article published on 5 June 2015

In vitro and in vivo pharmacological analysis of imidazole-free histamine H3 receptor antagonists: promising results for a brain-penetrating H3 blocker with weak anticholinesterase activity.

scientific article published on 22 May 2008

Inhibition of NaV1.6 sodium channel currents by a novel series of 1,4-disubstituted-triazole derivatives obtained via copper-catalyzed click chemistry.

scientific article

Microwave assisted efficient synthesis of imidazole-based privileged structures

scientific article

NMR analysis of a series of imidazobenzoxazines

scientific article published on 01 June 2010

Novel sodium channel antagonists in the treatment of neuropathic pain.

scientific article published on 17 November 2015

Recent advances in the medicinal chemistry of sodium channel blockers and their therapeutic potential.

scientific article published on January 2009

Sodium Channel Blockers as Therapeutic Target for Treating Epilepsy: Recent Updates ⬇️

scientific article published on January 1, 2012

Sodium channel blockers for neuropathic pain.

scientific article published on June 2010

Sodium channel blockers: a patent review (2010 - 2014).

scientific article published on 24 December 2014

Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release

scientific article

Synthesis and stability in biological media of 1H-imidazole-1-carboxylates of ROS203, an antagonist of the histamine H3 receptor.

scientific article

Synthesis, antioxidant activity and structure-activity relationships for a new series of 2-(N-acylaminoethyl)indoles with melatonin-like cytoprotective activity.

scientific article published in April 2006

List of works by Mirko Rivara

2,4(5)-Diarylimidazoles: synthesis and biological evaluation of a new class of sodium channel blockers against hNa(v)1.2.

2,4(5)-diarylimidazoles as inhibitors of hNaV1.2 sodium channels: pharmacological evaluation and structure-property relationships.

5-Benzylidene-hydantoins: synthesis and antiproliferative activity on A549 lung cancer cell line

Anticonvulsant activity of 2,4(1H)-diarylimidazoles in mice and rats acute seizure models ⬇️

Chiral NMR discrimination of the diastereoisomeric salts of the H3-antagonist 2-[3-(1H-imidazol-4-ylmethyl)piperidin-1-yl]-1H-benzimidazole.

Discovery of antitubercular 2,4-diphenyl-1H-imidazoles from chemical library repositioning and rational design

In vitro and in vivo pharmacological analysis of imidazole-free histamine H3 receptor antagonists: promising results for a brain-penetrating H3 blocker with weak anticholinesterase activity.

Inhibition of NaV1.6 sodium channel currents by a novel series of 1,4-disubstituted-triazole derivatives obtained via copper-catalyzed click chemistry.

Microwave assisted efficient synthesis of imidazole-based privileged structures

NMR analysis of a series of imidazobenzoxazines

Novel sodium channel antagonists in the treatment of neuropathic pain.

Recent advances in the medicinal chemistry of sodium channel blockers and their therapeutic potential.

Sodium Channel Blockers as Therapeutic Target for Treating Epilepsy: Recent Updates ⬇️

Sodium channel blockers for neuropathic pain.

Sodium channel blockers: a patent review (2010 - 2014).

Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release

Synthesis and stability in biological media of 1H-imidazole-1-carboxylates of ROS203, an antagonist of the histamine H3 receptor.

Synthesis, antioxidant activity and structure-activity relationships for a new series of 2-(N-acylaminoethyl)indoles with melatonin-like cytoprotective activity.