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List of works by Cecilia Garofalo

Akt2 inhibition enables the forkhead transcription factor FoxO3a to have a repressive role in estrogen receptor alpha transcriptional activity in breast cancer cells

scientific article

CD99 inhibits neural differentiation of human Ewing sarcoma cells and thereby contributes to oncogenesis

scientific article

Designing novel therapies against sarcomas in the era of personalized medicine and economic crisis.

scientific article published on January 2013

ERG deregulation induces IGF-1R expression in prostate cancer cells and affects sensitivity to anti-IGF-1R agents.

scientific article published on June 2015

Efficacy of and resistance to anti-IGF-1R therapies in Ewing's sarcoma is dependent on insulin receptor signaling

scientific article published on 31 January 2011

Estrogen receptor-alpha regulates the degradation of insulin receptor substrates 1 and 2 in breast cancer cells

scientific article

Expression of insulin-like growth factor system components in Ewing's sarcoma and their association with survival.

scientific article

Expression of nuclear insulin receptor substrate 1 in breast cancer

scientific article, published on August 2006

Expression of the insulin-like growth factor-I receptor in primary breast cancer and lymph node metastases: correlations with estrogen receptors alpha and beta.

scientific article published in November 2003

Functional significance of type 1 insulin-like growth factor-mediated nuclear translocation of the insulin receptor substrate-1 and beta-catenin.

scientific article published on 20 June 2005

Identification of common and distinctive mechanisms of resistance to different anti-IGF-IR agents in Ewing's sarcoma.

scientific article

Increased expression of leptin and the leptin receptor as a marker of breast cancer progression: possible role of obesity-related stimuli.

scientific article published in March 2006

Inhibition of cyclin D1 expression by androgen receptor in breast cancer cells--identification of a novel androgen response element

scientific article

Insulin receptor substrate 1 modulates the transcriptional activity and the stability of androgen receptor in breast cancer cells

scientific article

Insulin-like growth factor 1 differentially regulates estrogen receptor-dependent transcription at estrogen response element and AP-1 sites in breast cancer cells

scientific article published on 13 December 2006

Insulin-like growth factor 1 receptor affects the survival of primary prostate cancer patients depending on TMPRSS2-ERG status

scientific article

Interaction between estrogen receptor alpha and insulin/IGF signaling in breast cancer

scientific article

Leptin and cancer.

scientific article

Leptin interferes with the effects of the antiestrogen ICI 182,780 in MCF-7 breast cancer cells.

scientific article

Low calcium intake is associated with decreased adrenal androgens and reduced bone age in premenarcheal girls in the last pubertal stages.

scientific article published in January 2004

Metformin as an adjuvant drug against pediatric sarcomas: hypoxia limits therapeutic effects of the drug

scientific article (publication date: 2013)

Nuclear insulin receptor substrate 1 interacts with estrogen receptor alpha at ERE promoters

scientific article

Preclinical Effectiveness of Selective Inhibitor of IRS-1/2 NT157 in Osteosarcoma Cell Lines.

scientific article published on 13 May 2015

The estrogen receptor alpha:insulin receptor substrate 1 complex in breast cancer: structure-function relationships.

scientific article

Trabectedin Overrides Osteosarcoma Differentiative Block and Reprograms the Tumor Immune Environment Enabling Effective Combination with Immune Checkpoint Inhibitors

scientific article published on 9 June 2017

Trabectedin efficacy in Ewing sarcoma is greatly increased by combination with anti-IGF signaling agents.

scientific article