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List of works by Patrizia Romualdi

A new potent analgesic agent with reduced liability to produce morphine tolerance

scientific article published on 30 July 2015

Acute and chronic cannabinoid extracts administration affects motor function in a CREAE model of multiple sclerosis.

scientific article

Alghedon Fentanyl Transdermal System.

scientific article published on 25 November 2016

Alterations in prodynorphin gene expression and dynorphin levels in different brain regions after chronic administration of 14-methoxymetopon and oxycodone-6-oxime.

scientific article published on 2 June 2006

Antinociceptive activity of salmon calcitonin injected intrathecally in the rat

scientific article published on 01 March 1984

Assessment and treatment of breakthrough cancer pain: from theory to clinical practice

scientific article published on 12 September 2017

Binding profile of benextramine at neuropeptide Y receptor subtypes in rat brain areas

scientific article published on 01 November 1994

Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegeneration associated with Parkinson's disease.

scientific article published in October 2005

Chronic cocaine produces decreases in N/OFQ peptide levels in select rat brain regions

scientific article

Chronic delta 9-tetrahydrocannabinol during adolescence provokes sex-dependent changes in the emotional profile in adult rats: behavioral and biochemical correlates.

scientific article published on 2 January 2008

Chronic intracerebroventricular cocaine differentially affects prodynorphin gene expression in rat hypothalamus and caudate-putamen.

scientific article published in August 1996

Cocaine and ethanol target 26S proteasome activity and gene expression in neuroblastoma cells.

scientific article published on 16 February 2016

Combined exposure to agriculture pesticides, paraquat and maneb, induces alterations in the N/OFQ-NOPr and PDYN/KOPr systems in rats: Relevance to sporadic Parkinson's disease.

scientific article published on 23 December 2013

Distinguishable effects of intrathecal dynorphins, somatostatin, neurotensin and s-calcitonin on nociception and motor function in the rat

scientific article published on 01 October 1988

Distribution and characterization of VIP-related peptides in the rat spinal cord.

scientific article published in August 1990

Dynorphin/KOP and nociceptin/NOP gene expression and epigenetic changes by cocaine in rat striatum and nucleus accumbens.

scientific article published in November 2013

Early changes in prodynorphin mRNA and ir-dynorphin A levels after kindled seizures in the rat

scientific article published on 01 September 1995

Effects of acute ethanol exposure on class I HDACs family enzymes in wild-type and BDNF(+/-) mice

scientific article published on 28 August 2015

Effects of the selective norepinephrine uptake inhibitor nisoxetine on prodynorphin gene expression in rat CNS.

scientific article

Erratum to: What to Do, and What Not to Do, When Diagnosing and Treating Breakthrough Cancer Pain (BTcP): Expert Opinion

scientific article published on 7 April 2016

Ethanol and acetaldehyde exposure induces specific epigenetic modifications in the prodynorphin gene promoter in a human neuroblastoma cell line.

scientific article published on 24 November 2010

Ethanol induces epigenetic modulation of prodynorphin and pronociceptin gene expression in the rat amygdala complex.

scientific article published on 10 June 2012

Evidence of a PPARγ-mediated mechanism in the ability of Withania somnifera to attenuate tolerance to the antinociceptive effects of morphine

scientific article published on 29 November 2018

Human apolipoprotein E4 modulates the expression of Pin1, Sirtuin 1, and Presenilin 1 in brain regions of targeted replacement apoE mice

scientific article published on 23 October 2013

Increased expression of CRF and CRF-receptors in dorsal striatum, hippocampus, and prefrontal cortex after the development of nicotine sensitization in rats

article

Interplay between the Endogenous Opioid System and Proteasome Complex: Beyond Signaling ⬇️

scientific article published on 21 March 2019

Kainate seizures increase nociceptin/orphanin FQ release in the rat hippocampus and thalamus: a microdialysis study.

scientific article published in October 2004

Kainic acid down-regulates NOP receptor density and gene expression in human neuroblastoma SH-SY5Y cells.

scientific article published on 20 February 2008

Kindled seizure-induced c-fos and prodynorphin mRNA expressions are unrelated in the rat brain.

scientific article published in October 1996

Long-term exposure to opioid antagonists up-regulates prodynorphin gene expression in rat brain.

scientific article published in February 1995

Methamphetamine alters prodynorphin gene expression and dynorphin A levels in rat hypothalamus.

scientific article published in January 1999

Modification of anxiety‐like behaviors by nociceptin/orphanin FQ (N/OFQ) and time‐dependent changes in N/OFQ‐NOP gene expression following ethanol withdrawal ⬇️

scientific article published on July 15, 2012

Modulation of proorphaninFQ/N gene expression by morphine in the rat mesocorticolimbic system.

scientific article published in April 2002

Modulation of the Negative Affective Dimension of Pain: Focus on Selected Neuropeptidergic System Contributions

scientific article published on 17 August 2019

Morphine and Fentanyl Differently Affect MOP and NOP Gene Expression in Human Neuroblastoma SH-SY5Y Cells ⬇️

scientific article published on May 29, 2013

Mystic Acetaldehyde: The Never-Ending Story on Alcoholism

scientific article

N/OFQ system in brain areas of nerve-injured mice: its role in different aspects of neuropathic pain.

scientific article published on 21 December 2016

Nociceptin levels in the cerebrospinal fluid of chronic pain patients with or without intrathecal administration of morphine.

scientific article published in October 2006

Nociceptin/orphanin FQ prevents the antinociceptive action of paracetamol on the rat hot plate test.

scientific article published on 15 December 2004

On the Role of Peripheral Sensory and Gut Mu Opioid Receptors: Peripheral Analgesia and Tolerance

scientific article published on 26 May 2020

Opioid gene expression changes and post-translational histone modifications at promoter regions in the rat nucleus accumbens after acute and repeated 3,4-methylenedioxy-methamphetamine (MDMA) exposure.

scientific article published on 29 October 2016

Opioid receptor gene expression in human neuroblastoma SH-SY5Y cells following tapentadol exposure

scientific article published on 4 February 2014

Peripheral leukocyte expression of the potential biomarker proteins Bdnf, Sirt1, and Psen1 is not regulated by promoter methylation in Alzheimer's disease patients.

scientific article published on 11 August 2015

Pharmacological rationale for tapentadol therapy: a review of new evidence

scientific article published on 16 May 2019

Pin1 contribution to Alzheimer's disease: transcriptional and epigenetic mechanisms in patients with late-onset Alzheimer's disease.

scientific article published on 17 January 2012

Possible mediation of catecholaminergic pathways in the antinociceptive effect of an extract of Cannabis sativa L

scientific article published on 01 January 1986

Proteasome subunit and opioid receptor gene expression down-regulation induced by paraquat and maneb in human neuroblastoma SH-SY5Y cells

scientific article published on 3 October 2015

Protection by opioids against gastric lesions caused by necrotizing agents

scientific article published on 01 January 1988

Regional distribution of immunoreactive dynorphin A in the human gastrointestinal tract

scientific article published on 01 April 1988

Regulation of dynorphin gene expression by kappa-opioid agonist treatment.

scientific article

Regulation of opioid gene expression in the rat brainstem by 3,4-methylenedioxymethamphetamine (MDMA): role of serotonin and involvement of CREB and ERK cascade.

scientific article published on 23 December 2010

Repeated nicotine exposure modulates prodynorphin and pronociceptin levels in the reward pathway.

scientific article published on 12 July 2016

Reply-Letter to the Editor: What to Do, and What Not to Do, When Diagnosing and Treating Breakthrough Cancer Pain (BTcP): Expert Opinion

scientific article published on 20 June 2016

Role of serotonin in the regulation of the dynorphinergic system by a kappa-opioid agonist and cocaine treatment in rat CNS

scientific article

Safe Use of Opioids in Chronic Kidney Disease and Hemodialysis Patients: Tips and Tricks for Non-Pain Specialists

scientific article published on 09 September 2020

Selective DNA methylation of BDNF promoter in bipolar disorder: differences among patients with BDI and BDII.

scientific article

Short-term withdrawal from repeated exposure to cocaine during adolescence modulates dynorphin mRNA levels and BDNF signaling in the rat nucleus accumbens

scientific article published on 13 February 2019

Studies on the antinociceptive effect of intrathecal salmon calcitonin

scientific article published on 01 January 1985

Substance P is diminished and vasoactive intestinal peptide is augmented in psoriatic lesions and these peptides exert disparate effects on the proliferation of cultured human keratinocytes

scientific article published on 01 April 1992

Substance P levels are decreased in lesional skin of atopic dermatitis

scientific article published on 01 October 1992

Supraspinal and spinal effects of [Phe1psi(CH2-NH)Gly2]-nociceptin(1-13)-NH2 on nociception in the rat

Tapentadol for neuropathic pain: a review of clinical studies

scientific article published on 16 May 2019

The challenge of perioperative pain management in opioid-tolerant patients

scientific article published on 5 September 2017

The kappa-opioid receptor agonist U-69593 prevents cocaine-induced phosphorylation of DARPP-32 at Thr(34) in the rat brain.

scientific article

The opioid antagonist naloxone influences prodynorphin gene expression.

scientific article

The standardized Withania somnifera Dunal root extract alters basal and morphine-induced opioid receptor gene expression changes in neuroblastoma cells.

scientific article published on 10 January 2018

Transcriptional and epigenetic phenomena in peripheral blood cells of monozygotic twins discordant for alzheimer's disease, a case report

scientific article published on 24 November 2016

Treatment with the neurotoxic Aβ (25-35) peptide modulates the expression of neuroprotective factors Pin1, Sirtuin 1, and brain-derived neurotrophic factor in SH-SY5Y human neuroblastoma cells

scientific article published on 22 February 2016

Vasoactive intestinal polypeptide carboxy-terminal fragment, VIP(22-28), and other fragments of VIP, in the central nervous system of the rat

scientific article published on 01 May 1989

What to Do, and What Not to Do, When Diagnosing and Treating Breakthrough Cancer Pain (BTcP): Expert Opinion

scientific article

∆(9)-Tetrahydrocannabinol decreases NOP receptor density and mRNA levels in human SH-SY5Y cells.

scientific article published on 21 May 2011

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