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List of works by Iryna Leshchyns'ka

Age-dependent loss of parvalbumin-expressing hippocampal interneurons in mice deficient in CHL1, a mental retardation and schizophrenia susceptibility gene

scientific article published on 18 August 2015

Aβ-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease

scientific article

CHL1 is a selective organizer of the presynaptic machinery chaperoning the SNARE complex

scientific article

Cell adhesion and intracellular calcium signaling in neurons.

scientific article published on 13 December 2013

Cellular form of prion protein inhibits Reelin-mediated shedding of Caspr from the neuronal cell surface to potentiate Caspr-mediated inhibition of neurite outgrowth

scientific article published on July 2010

Clustering of the neural cell adhesion molecule (NCAM) at the neuronal cell surface induces caspase-8- and -3-dependent changes of the spectrin meshwork required for NCAM-mediated neurite outgrowth

scientific article

Glial Scar Expression of CHL1, the Close Homolog of the Adhesion Molecule L1, Limits Recovery after Spinal Cord Injury

scientific article published on 01 July 2007

Immobilized pool of NCAM180 in the postsynaptic membrane is homeostatically replenished by the flux of NCAM180 from extrasynaptic regions.

scientific article

L1CAM increases MAP2 expression via the MAPK pathway to promote neurite outgrowth.

scientific article

NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth.

scientific article published on September 2008

NCAM promotes assembly and activity-dependent remodeling of the postsynaptic signaling complex.

scientific article

NCAM/Spectrin Complex Disassembly Results in PSD Perforation and Postsynaptic Endocytic Zone Formation

scientific article published on February 21, 2011

Neural cell adhesion molecule (NCAM) association with PKCbeta2 via betaI spectrin is implicated in NCAM-mediated neurite outgrowth.

scientific article

Neural cell adhesion molecule 2 promotes the formation of filopodia and neurite branching by inducing submembrane increases in Ca2+ levels.

scientific article published in January 2015

PI4KIIα phosphorylation by GSK3 directs vesicular trafficking to lysosomes.

scientific article published in November 2014

Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth.

scientific article

RPTPalpha is essential for NCAM-mediated p59fyn activation and neurite elongation.

scientific article

The adhesion molecule CHL1 regulates uncoating of clathrin-coated synaptic vesicles

scientific article published in December 2006

The neural cell adhesion molecule (NCAM) associates with and signals through p21-activated kinase 1 (Pak1).

scientific article published in January 2013

The neural cell adhesion molecule promotes FGFR-dependent phosphorylation and membrane targeting of the exocyst complex to induce exocytosis in growth cones

scientific journal article

The neural cell adhesion molecule promotes maturation of the presynaptic endocytotic machinery by switching synaptic vesicle recycling from adaptor protein 3 (AP-3)- to AP-2-dependent mechanisms.

scientific article published in October 2013

Trans-Golgi network delivery of synaptic proteins in synaptogenesis

scientific article published on January 2004