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List of works by Mark E Schurdak

A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine.

scientific article published on 08 March 2016

A Quantitative Systems Pharmacology Approach to Infer Pathways Involved in Complex Disease Phenotypes

scientific article published on 01 January 2018

A metric and workflow for quality control in the analysis of heterogeneity in phenotypic profiles and screens

scientific article published on 14 October 2015

Adaptation of an in vitro phospholipidosis assay to an automated image analysis system

scientific article published on 01 January 2007

Applications of the microphysiology systems database for experimental ADME-Tox and disease models

scientific article published on 25 March 2020

Biologically Relevant Heterogeneity: Metrics and Practical Insights

scientific article published on 06 January 2017

Comparison of 32P-postlabeling and high pressure liquid chromatographic analyses for 7,12-dimethylbenz[a]anthracene--DNA adducts

scientific article published on 01 April 1988

Comparison of three cell-based drug screening platforms for HSV-1 infection

scientific article published on 22 March 2017

Complex gel permeation assays for screening combinatorial libraries.

scientific article

Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington's Disease Model through the Application of Quantitative Systems Pharmacology.

scientific article published on 19 December 2017

From bacterial genomes to novel antibacterial agents: discovery, characterization, and antibacterial activity of compounds that bind to HI0065 (YjeE) from Haemophilus influenzae

scientific article published on 01 June 2007

High content screen microscopy analysis of A beta 1-42-induced neurite outgrowth reduction in rat primary cortical neurons: neuroprotective effects of alpha 7 neuronal nicotinic acetylcholine receptor ligands.

scientific article published on 24 March 2007

High expression of orphan nuclear receptor NR4A1 in a subset of ovarian tumors with worse outcome.

scientific article published on 02 March 2016

Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen.

scientific article

Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery

scientific article (publication date: 2014)

Integrating Analysis of Cellular Heterogeneity in High-Content Dose-Response Studies

scientific article published in January 2018

Kinase drug discovery by affinity selection/mass spectrometry (ASMS): application to DNA damage checkpoint kinase Chk1

scientific article published on 06 September 2006

Kinome siRNA-phosphoproteomic screen identifies networks regulating AKT signaling

scientific article published on 13 June 2011

Large-scale generation of human iPSC-derived neural stem cells/early neural progenitor cells and their neuronal differentiation

scientific article published in January 2014

Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors

scientific article

RNAi-based screening of the human kinome identifies Akt-cooperating kinases: a new approach to designing efficacious multitargeted kinase inhibitors.

scientific article published in March 2006

Role of Rho kinase pathway in chondroitin sulfate proteoglycan-mediated inhibition of neurite outgrowth in PC12 cells

scientific article published in August 2008

Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion

scientific article

Survivin depletion preferentially reduces the survival of activated K-Ras-transformed cells.

scientific article published in January 2007

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