List of works - Inchan Kwon

A chemical chaperone-based drug candidate is effective in a mouse model of amyotrophic lateral sclerosis (ALS).

scientific article published on 13 March 2015

A revisited folding reporter for quantitative assay of protein misfolding and aggregation in mammalian cells

scientific article

Bioconjugation and Active Site Design of Enzymes Using Non-natural Amino Acids

Bioconjugation of therapeutic proteins and enzymes using the expanded set of genetically encoded amino acids

scientific article

Cis-suppression to arrest protein aggregation in mammalian cells.

scientific article

Comparative studies of the serum half-life extension of a protein via site-specific conjugation to a species-matched or -mismatched albumin

scholarly article by Byungseop Yang et al published 2018 in Biomaterials Science

Controlling enzyme inhibition using an expanded set of genetically encoded amino acids

scientific article

Determining binding sites of polycyclic aromatic small molecule-based amyloid-beta peptide aggregation modulators using sequence-specific antibodies

scientific article

Development of the radical-stable Coprinus cinereus peroxidase (CiP) by blocking the radical attack

scientific article published on 6 September 2014

Different fates of Alzheimer's disease amyloid-β fibrils remodeled by biocompatible small molecules

scientific article published on 3 December 2012

Double clicking for site-specific coupling of multiple enzymes

scientific article

Effects of Non-Natural Amino Acid Incorporation into the Enzyme Core Region on Enzyme Structure and Function

scientific article

Efficient loading of ophthalmic drugs with poor loadability into contact lenses using functional comonomers

scholarly article by Dasom Lee et al published 2018 in Biomaterials Science

Enhanced production of Dopa-incorporated mussel adhesive protein using engineered translational machineries

scientific article published on 20 March 2020

Generation of therapeutic protein variants with the human serum albumin binding capacity via site-specific fatty acid conjugation

scientific article published on 21 December 2017

Halogenation generates effective modulators of amyloid-Beta aggregation and neurotoxicity

scientific article

Intramolecular distance in the conjugate of urate oxidase and fatty acid governs FcRn binding and serum half-life in vivo

scientific article published on 30 January 2020

Manipulating the substrate specificity of murine dihydrofolate reductase enzyme using an expanded set of amino acids

scholarly article by Shun Zheng et al published July 2015 in Biochemical Engineering Journal

Oral Triphenylmethane Food Dye Analog, Brilliant Blue G, Prevents Neuronal Loss in APPSwDI/NOS2-/- Mouse Model

scientific article

Positional effects of hydrophobic non-natural amino acid mutagenesis into the surface region of murine dihydrofolate reductase on enzyme properties

scholarly article by H. Edward Wong et al published May 2016 in Biochemical Engineering Journal

Recombinant Peptide Production Platform Coupled with Site-Specific Albumin Conjugation Enables a Convenient Production of Long-Acting Therapeutic Peptide

scientific article published on 16 April 2020

Site-specific albumination of a therapeutic protein with multi-subunit to prolong activity in vivo

scientific article

Site-specific bioconjugation of a murine dihydrofolate reductase enzyme by copper(I)-catalyzed azide-alkyne cycloaddition with retained activity

scientific article

Site-specific bioconjugation of an organometallic electron mediator to an enzyme with retained photocatalytic cofactor regenerating capacity and enzymatic activity.

scientific article

Site-specific fatty acid-conjugation to prolong protein half-life in vivo

scientific article

Suppressing mutation-induced protein aggregation in mammalian cells by mutating residues significantly displaced upon the original mutation

scientific article

Tailoring the substrate specificity of yeast phenylalanyl-tRNA synthetase toward a phenylalanine analog using multiple-site-specific incorporation

scientific article

Techniques for Monitoring Protein Misfolding and Aggregation in Vitro and in Living Cells

scientific article

Temporal Control of Efficient In Vivo Bioconjugation Using a Genetically Encoded Tetrazine-Mediated Inverse-Electron-Demand Diels-Alder Reaction

scientific article published on 09 October 2020

The Minimal Effect of Linker Length for Fatty Acid Conjugation to a Small Protein on the Serum Half-Life Extension

scientific article published on 26 April 2020

List of works by Inchan Kwon

A chemical chaperone-based drug candidate is effective in a mouse model of amyotrophic lateral sclerosis (ALS).

A revisited folding reporter for quantitative assay of protein misfolding and aggregation in mammalian cells

Bioconjugation and Active Site Design of Enzymes Using Non-natural Amino Acids

Bioconjugation of therapeutic proteins and enzymes using the expanded set of genetically encoded amino acids

Cis-suppression to arrest protein aggregation in mammalian cells.

Comparative studies of the serum half-life extension of a protein via site-specific conjugation to a species-matched or -mismatched albumin

Controlling enzyme inhibition using an expanded set of genetically encoded amino acids

Determining binding sites of polycyclic aromatic small molecule-based amyloid-beta peptide aggregation modulators using sequence-specific antibodies

Development of the radical-stable Coprinus cinereus peroxidase (CiP) by blocking the radical attack

Different fates of Alzheimer's disease amyloid-β fibrils remodeled by biocompatible small molecules

Double clicking for site-specific coupling of multiple enzymes

Effects of Non-Natural Amino Acid Incorporation into the Enzyme Core Region on Enzyme Structure and Function

Efficient loading of ophthalmic drugs with poor loadability into contact lenses using functional comonomers

Enhanced production of Dopa-incorporated mussel adhesive protein using engineered translational machineries

Generation of therapeutic protein variants with the human serum albumin binding capacity via site-specific fatty acid conjugation

Halogenation generates effective modulators of amyloid-Beta aggregation and neurotoxicity

Intramolecular distance in the conjugate of urate oxidase and fatty acid governs FcRn binding and serum half-life in vivo

Manipulating the substrate specificity of murine dihydrofolate reductase enzyme using an expanded set of amino acids

Oral Triphenylmethane Food Dye Analog, Brilliant Blue G, Prevents Neuronal Loss in APPSwDI/NOS2-/- Mouse Model

Positional effects of hydrophobic non-natural amino acid mutagenesis into the surface region of murine dihydrofolate reductase on enzyme properties

Recombinant Peptide Production Platform Coupled with Site-Specific Albumin Conjugation Enables a Convenient Production of Long-Acting Therapeutic Peptide

Site-specific albumination of a therapeutic protein with multi-subunit to prolong activity in vivo

Site-specific bioconjugation of a murine dihydrofolate reductase enzyme by copper(I)-catalyzed azide-alkyne cycloaddition with retained activity

Site-specific bioconjugation of an organometallic electron mediator to an enzyme with retained photocatalytic cofactor regenerating capacity and enzymatic activity.

Site-specific fatty acid-conjugation to prolong protein half-life in vivo

Suppressing mutation-induced protein aggregation in mammalian cells by mutating residues significantly displaced upon the original mutation

Tailoring the substrate specificity of yeast phenylalanyl-tRNA synthetase toward a phenylalanine analog using multiple-site-specific incorporation

Techniques for Monitoring Protein Misfolding and Aggregation in Vitro and in Living Cells

Temporal Control of Efficient In Vivo Bioconjugation Using a Genetically Encoded Tetrazine-Mediated Inverse-Electron-Demand Diels-Alder Reaction

The Minimal Effect of Linker Length for Fatty Acid Conjugation to a Small Protein on the Serum Half-Life Extension