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List of works by Franco Folli

A functional variant of the adipocyte glycerol channel aquaporin 7 gene is associated with obesity and related metabolic abnormalities

scientific article published on 9 March 2007

Acute promyelocytic leukemia following mitoxantrone as single agent for the treatment of multiple sclerosis

scientific article published on 01 March 1998

Alfa and beta estrogen receptors and the biliary tree

scientific article

Altered insulin receptor signalling and β-cell cycle dynamics in type 2 diabetes mellitus

scientific article

Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk

scientific article

Antitumorigenic and antiinsulinogenic effects of calcitriol on insulinoma cells and solid beta-cell tumors

scientific article published on October 2002

Apoptotic/mytogenic pathways during human heart development

scientific article

Asymptomatic hyperinsulinemic hypoglycemia after gastric banding.

scientific article published in December 2005

Autoantibodies to Amphiphysin I and Amphiphysin II in a Patient with Sensory-Motor Neuropathy

scientific article published on 01 January 2002

Autoantibodies to GABA-ergic neurons and pancreatic beta cells in stiff-man syndrome

scientific article published on May 1990

Autoantibodies to a 128-kd synaptic protein in three women with the stiff-man syndrome and breast cancer

scientific article published in February 1993

Autoantibodies to glutamic acid decarboxylase in a patient with stiff-man syndrome, epilepsy, and type I diabetes mellitus

scientific article

Bariatric surgery and bone disease: from clinical perspective to molecular insights.

scientific article published on 17 July 2012

Biliary pancreatic diversion and laparoscopic adjustable gastric banding in morbid obesity: their long-term effects on metabolic syndrome and on cardiovascular parameters

scientific article published on 20 July 2009

C-174G polymorphism in the promoter of the interleukin-6 gene is associated with insulin resistance.

scientific article published in August 2005

Changes in lipid levels with percent of weight loss in morbid obesity

scientific article

Chemical mediator of insulin action stimulates lipid synthesis and down regulates the insulin receptors in primary cultures of rat hepatocytes

scientific article published on 01 August 1983

Chronic continuous exenatide infusion does not cause pancreatic inflammation and ductal hyperplasia in non-human primates

scientific article

Chronic hyperglycemia impairs insulin secretion by affecting insulin receptor expression, splicing, and signaling in RIN β‐cell line and human islets of Langerhans ⬇️

scientific article published on May 8, 2003

Circulating IGF-I and IGFBP3 Levels Control Human Colonic Stem Cell Function and Are Disrupted in Diabetic Enteropathy

scientific article

Circulating fibroblast growth factor-21 is elevated in impaired glucose tolerance and type 2 diabetes and correlates with muscle and hepatic insulin resistance.

scientific article published on June 2009

Circulating leptin correlates with left ventricular mass in morbid (grade III) obesity before and after weight loss induced by bariatric surgery: a potential role for leptin in mediating human left ventricular hypertrophy

scientific article published on 26 April 2005

Coordinated defects in hepatic long chain fatty acid metabolism and triglyceride accumulation contribute to insulin resistance in non-human primates

scientific article

Delta cell death in the islet of Langerhans and the progression from normal glucose tolerance to type 2 diabetes in non-human primates (baboon, Papio hamadryas).

scientific article published on 7 June 2015

Deranged platelet calcium homeostasis in poorly controlled IDDM patients

scientific article published on 01 January 1993

Development and characterization of pituitary GH3 cell clones stably transfected with a human proinsulin cDNA.

scientific article

Dietary Intake of Proteins and Calories Is Inversely Associated With The Oxidation State of Plasma Thiols in End-Stage Renal Disease Patients.

scientific article

Disproportionate hyperproinsulinemia, beta-cell restricted prohormone convertase 2 deficiency, and cell cycle inhibitors expression by human islets transplanted into athymic nude mice: insights into nonimmune-mediated mechanisms of delayed islet gra

scientific article

Distinct regulation of hypothalamic and brown/beige adipose tissue activities in human obesity.

scientific article published on 21 May 2015

Duodenal adipose tissue is associated with obesity in baboons (Papio sp): a novel site of ectopic fat deposition in non-human primates

scientific article published on 23 January 2019

Ectopic fat storage, insulin resistance, and hypertension.

scientific article published on January 2011

Effect of acute physiological hyperinsulinemia on gene expression in human skeletal muscle in vivo

scientific article published on 11 March 2008

Effect of short-term free Fatty acids elevation on mitochondrial function in skeletal muscle of healthy individuals

scientific article

Effects of weight loss in metabolically healthy obese subjects after laparoscopic adjustable gastric banding and hypocaloric diet

scientific article

Elevated concentrations of liver enzymes and ferritin identify a new phenotype of insulin resistance: effect of weight loss after gastric banding

scientific article published on 24 September 2008

Energy expenditure evaluation in humans and non-human primates by SenseWear Armband. Validation of energy expenditure evaluation by SenseWear Armband by direct comparison with indirect calorimetry

scientific article

Erratum: Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

scientific article published in Nature

Erythrocytosis in a patient with chronic obstructive pulmonary disease ⬇️

scientific article published on 01 February 1998

Estrogens stimulate proliferation of intrahepatic biliary epithelium in rats

scientific article published on 01 December 2000

Evidence for the involvement of phosphatidylinositol 3-kinase in fMLP-stimulated neutrophil adhesion to ICAM-1-transfected cells.

scientific article published on June 2001

Extramedullary myeloid cell tumor/granulocytic sarcoma with predilection for serosal surfaces

scientific article published on 01 March 2002

GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion.

scientific article published on May 1991

Glutathione redox potential is low and glutathionylated and cysteinylated hemoglobin levels are elevated in maintenance hemodialysis patients.

scientific article published on 17 January 2013

High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: a potential role for regulation of specific Bcl family genes toward an apoptotic cell death program

scientific article (publication date: June 2001)

Human stiff-person syndrome IgG induces anxious behavior in rats

scientific article

Hyperglycemia-induced oxidative stress and its role in diabetes mellitus related cardiovascular diseases

scientific article published on January 2013

Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase ⬇️

scientific article published on September 13, 1990

Impact of obesity severity and duration on pancreatic β- and α-cell dynamics in normoglycemic non-human primates.

scientific article published on 11 December 2012

Impact of tobacco smoking on lipid metabolism, body weight and cardiometabolic risk

scientific article published on January 2010

Impairment of body mass reduction-associated activation of brown/beige adipose tissue in patients with type 2 diabetes mellitus.

scientific article

In vivo and in vitro studies of vanadate in human and rodent diabetes mellitus

scientific article published on December 1995

Increased airway reactivity and hyperinsulinemia in obese mice are linked by ERK signaling in brain stem cholinergic neurons.

scientific article

Increased carotid intima-media thickness in the physiologic range is associated with impaired postprandial glucose metabolism, insulin resistance and beta cell dysfunction.

scientific article published on 6 June 2013

Increased levels of the Akt-specific phosphatase PH domain leucine-rich repeat protein phosphatase (PHLPP)-1 in obese participants are associated with insulin resistance.

scientific article published on April 2011

Insulin and insulin-like growth factor-1 stimulate proliferation and type I collagen accumulation by human hepatic stellate cells: differential effects on signal transduction pathways

scientific article published on 01 June 1999

Insulin receptor substrate-1 (IRS-1) distribution in the rat central nervous system.

scientific article

Insulin resistance and endothelial dysfunction: a mutual relationship in cardiometabolic risk

scientific article published on January 2013

Insulin resistance in uremia: in vitro model in the rat liver using human serum to study mechanisms

scientific article published in November 1986

Insulin signalling in heart involves insulin receptor substrates-1 and -2, activation of phosphatidylinositol 3-kinase and the JAK 2-growth related pathway

scientific article published on 01 October 1998

Insulin-secreting pituitary GH3 cells: a potential beta-cell surrogate for diabetes cell therapy

scientific article published on 01 November 2000

Interaction between leptin and insulin signaling pathways differentially affects JAK-STAT and PI 3-kinase-mediated signaling in rat liver.

scientific article published in January 2003

Intracellular pathways mediating estrogen-induced cholangiocyte proliferation in the rat.

scientific article published in August 2002

Is it worth treating diabetes? Lessons from the UKPDS. United Kingdom Prospective Diabetes Study

scientific article published on 01 December 1998

Islet transplantation improves vascular diabetic complications in patients with diabetes who underwent kidney transplantation: a comparison between kidney-pancreas and kidney-alone transplantation

scientific article published on 01 April 2003

Islet transplantation is associated with an improvement of cardiovascular function in type 1 diabetic kidney transplant patients

scientific article

Islet transplantation is associated with improvement of renal function among uremic patients with type I diabetes mellitus and kidney transplants

scientific article published in August 2003

Islet transplantation stabilizes hemostatic abnormalities and cerebral metabolism in individuals with type 1 diabetes.

scientific article published on 11 September 2013

Islet-Derived eATP Fuels Autoreactive CD8+ T Cells and Facilitates the Onset of Type 1 Diabetes

scientific article published on 31 July 2018

Laparoscopic adjustable gastric banding for the treatment of morbid (grade 3) obesity and its metabolic complications: a three-year study.

scientific article published in August 2002

Laparoscopic gastric banding prevents type 2 diabetes and arterial hypertension and induces their remission in morbid obesity: a 4-year case-controlled study.

scientific article

Long-lasting remission of type 1 diabetes following treatment with topiramate for generalized seizures

scientific article published on 19 February 2011

Long-term beneficial effect of islet transplantation on diabetic macro-/microangiopathy in type 1 diabetic kidney-transplanted patients.

scientific article published in April 2003

Medical therapy of aortic aneurysms: a pathophysiology-based approach

scientific article published on 01 September 2011

Membranous nephropathy and cerebellar degeneration with anti-GAD antibodies in type 2 diabetes mellitus.

scientific article published on 10 March 2015

Metabolic aspects of bariatric surgery.

scientific article published on May 2007

Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies ⬇️

scientific article published on November 1, 1995

Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats

scientific article

Morphological and functional differences in haemostatic axis between kidney transplanted and end-stage renal disease patients

scientific article published on September 2005

Morphological and ultrastructural features of human islet grafts performed in diabetic nude mice

scientific article published in November 2005

Natural history of kidney graft survival, hypertrophy, and vascular function in end-stage renal disease type 1 diabetic kidney-transplanted patients: beneficial impact of pancreas and successful islet cotransplantation

scientific article published in June 2005

Neurotransmitter-hormonal responses to psychological stress in peripubertal subjects: relationship to aggressive behavior.

scientific article published in January 1998

Neurotransmitters and Neuropeptides: New Players in the Control of Islet of Langerhans' Cell Mass and Function

scientific article published on 31 August 2015

Nitric oxide inhibits thrombin receptor-activating peptide-induced phosphoinositide 3-kinase activity in human platelets

scientific article published on 01 May 1999

Normalization of multiple hemostatic abnormalities in uremic type 1 diabetic patients after kidney-pancreas transplantation

scientific article published on 01 September 2004

Obesity modulates the expression of haptoglobin in the white adipose tissue via TNFalpha.

scientific article

PET evidence of central GABAergic changes in stiff-person syndrome.

scientific article

Pancreatic islet amyloidosis, beta-cell apoptosis, and alpha-cell proliferation are determinants of islet remodeling in type-2 diabetic baboons

scientific article published on 30 July 2009

Pancreatic islet of Langerhans' cytoarchitecture and ultrastructure in normal glucose tolerance and in type 2 diabetes mellitus

scientific article published on 01 September 2018

Paraneoplastic autoimmune xerostomia

scientific article published on 01 July 1997

Paraneoplastic insulin resistance syndrome in advanced aggressive fibromatosis (desmoid tumor) treated by imatinib mesylate.

scientific article published in September 2006

Patients' Expectations are Important for Success in Bariatric Surgery

scientific article published on 01 September 2017

Physiological and molecular determinants of insulin action in the baboon.

scientific article published on 3 January 2008

Pioglitazone improves glucose metabolism and modulates skeletal muscle TIMP-3-TACE dyad in type 2 diabetes mellitus: a randomised, double-blind, placebo-controlled, mechanistic study

scientific article

Pioglitazone treatment increases food intake and decreases energy expenditure partially via hypothalamic adiponectin/adipoR1/AMPK pathway.

scientific article published on 31 July 2015

Placental proteome abnormalities in women with gestational diabetes and large-for-gestational-age newborns

scientific article published on 01 November 2020

Plasma leptin levels and coronary heart disease

scientific article published on 01 August 2002

Plasmapheresis in the treatment of stiff-man syndrome

scientific article published on 01 June 1989

Platelet calcium homeostasis is abnormal in patients with severe arteriosclerosis

scientific article published on 01 September 1994

Post-surgery adherence to scheduled visits and compliance, more than personality disorders, predict outcome of bariatric restrictive surgery in morbidly obese patients

scientific article published in November 2007

Potential use of exenatide for the treatment of obesity

scientific article

Predictive models of insulin resistance derived from simple morphometric and biochemical indices related to obesity and the metabolic syndrome in baboons

scientific article published on 23 April 2009

Proteomics reveals novel oxidative and glycolytic mechanisms in type 1 diabetic patients' skin which are normalized by kidney-pancreas transplantation

scientific article

Regulation of ERK/JNK/p70S6K in two rat models of liver injury and fibrosis

scientific article published on October 2003

Regulation of endocytic-transcytotic pathways and bile secretion by phosphatidylinositol 3-kinase in rats.

scientific article published on September 1997

Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus

scientific article

Reply to letter to the editor by Bonaventura et al

scientific article published on 24 June 2019

Retinol-binding protein 4 is associated with impaired glucose tolerance but not with whole body or hepatic insulin resistance in Mexican Americans

scientific article published on 3 February 2009

Sclerostin and Insulin Resistance in Prediabetes: Evidence of a Cross Talk Between Bone and Glucose Metabolism.

scientific article published on 17 June 2015

Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial

scientific article (publication date: 8 October 2005)

Sitagliptin Treatment at the Time of Hospitalization Was Associated With Reduced Mortality in Patients With Type 2 Diabetes and COVID-19: A Multicenter, Case-Control, Retrospective, Observational Study

scientific article published on 29 September 2020

Spinal epidural abscess: treatment options

scientific article published on 01 July 1998

Sympathetic overactivity, endothelial dysfunction, inflammation, and metabolic abnormalities cluster in grade III (World Health Organization) obesity: reversal through sustained weight loss obtained with laparoscopic adjustable gastric banding.

scientific article published in December 2006

TLR4 at the Crossroads of Nutrients, Gut Microbiota, and Metabolic Inflammation.

scientific article published on 26 March 2015

The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes.

scientific article

The GLP-1 receptor agonists exenatide and liraglutide activate Glucose transport by an AMPK-dependent mechanism.

scientific article published on 30 July 2016

The crosstalk between insulin and renin-angiotensin-aldosterone signaling systems and its effect on glucose metabolism and diabetes prevention.

scientific article

The early intracellular signaling pathway for the insulin/insulin-like growth factor receptor family in the mammalian central nervous system

scientific article published on October 1996

The glial glutamate transporter 1 (GLT1) is expressed by pancreatic beta-cells and prevents glutamate-induced beta-cell death

scientific article

The inflammatory status score including IL-6, TNF-α, osteopontin, fractalkine, MCP-1 and adiponectin underlies whole-body insulin resistance and hyperglycemia in type 2 diabetes mellitus

scientific article published on 27 December 2013

The insulin receptor and its substrate: molecular determinants of early events in insulin action.

scientific article

The mitochondrial Italian Human Proteome Project initiative (mt-HPP).

scientific article published on 28 May 2013

The multi-faceted cross-talk between the insulin and angiotensin II signaling systems.

scientific article

The ontogeny of the endocrine pancreas in the fetal/newborn baboon

scientific article published on 21 June 2012

The potential role of glutamate in the current diabetes epidemic.

scientific article published on 05 January 2012

The role of nateglinide and repaglinide, derivatives of meglitinide, in the treatment of type 2 diabetes mellitus.

scientific article published on 30 April 2013

The role of oxidative stress in the pathogenesis of type 2 diabetes mellitus micro- and macrovascular complications: avenues for a mechanistic-based therapeutic approach.

scientific article published on September 2011

Ultrasound measurement of visceral and subcutaneous fat in morbidly obese patients before and after laparoscopic adjustable gastric banding: comparison with computerized tomography and with anthropometric measurements

scientific article published on 01 October 2002

Vitamin D, sub-inflammation and insulin resistance. A window on a potential role for the interaction between bone and glucose metabolism.

scientific article published on 13 April 2017

Weight loss through gastric banding: effects on TSH and thyroid hormones in obese subjects with normal thyroid function

scientific article published on 15 October 2009

White blood cells in obesity and diabetes: effects of weight loss and normalization of glucose metabolism.

scientific article published in October 2004

[Stiff-man syndrome and type I diabetes mellitus: a common autoimmune pathogenesis?]

scientific article published on 01 January 1988

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