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List of works by Rafael Mayoral

Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity

scientific article published on 5 March 2015

Catestatin Inhibits Obesity-Induced Macrophage Infiltration and Inflammation in the Liver and Suppresses Hepatic Glucose Production Leading to Improved Insulin Sensitivity.

scientific article published on 6 February 2018

Caveolin-1 is required for TGF-β-induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE/ADAM17.

scientific article

Caveolin-1-dependent activation of the metalloprotease TACE/ADAM17 by TGF-β in hepatocytes requires activation of Src and the NADPH oxidase NOX1.

scientific article published on 27 January 2016

Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice

scientific article published on 14 October 2014

Constitutive expression of cyclo-oxygenase 2 transgene in hepatocytes protects against liver injury

scientific article

Cyclo-oxygenase 2 expression impairs serum-withdrawal-induced apoptosis in liver cells.

scientific article published on September 2006

Cyclooxygenase-2 expression in hepatocytes attenuates non-alcoholic steatohepatitis and liver fibrosis in mice.

scientific article published on 14 June 2016

Cyclooxygenase-2 is a target of microRNA-16 in human hepatoma cells

scientific article

Differential regulation of hepatic physiology and injury by the TAM receptors Axl and Mer

scientific article published on 22 June 2020

Dispensability and dynamics of caveolin-1 during liver regeneration and in isolated hepatic cells.

scientific article

Distinct Hepatic Macrophage Populations in Lean and Obese Mice

scientific article

Evaluation of epigenetic modulation of cyclooxygenase-2 as a prognostic marker for hepatocellular carcinoma

scientific article

GPR43 Potentiates β-Cell Function in Obesity

scientific article published on 28 May 2015

Hepatic cyclooxygenase-2 expression protects against diet-induced steatosis, obesity, and insulin resistance.

scientific article published on 24 November 2014

Hepatic insulin resistance is associated with increased apoptosis and fibrogenesis in nonalcoholic steatohepatitis and chronic hepatitis C.

scientific article published on 27 August 2010

Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD.

scientific article published on 17 April 2014

Impairment of transforming growth factor beta signaling in caveolin-1-deficient hepatocytes: role in liver regeneration.

scientific article

Omega-3 fatty acids reduce obesity-induced tumor progression independent of GPR120 in a mouse model of postmenopausal breast cancer.

scientific article

Progression of liver oncogenesis in the double transgenic mice c-myc/TGF α is not enhanced by cyclooxygenase-2 expression.

scientific article published on 8 April 2013

Prostaglandin E2 promotes migration and adhesion in hepatocellular carcinoma cells.

scientific article published on 20 January 2005

Protection against Fas-induced liver apoptosis in transgenic mice expressing cyclooxygenase 2 in hepatocytes

article

Protein Tyrosine Phosphatase 1B (PTP1B) deficiency accelerates hepatic regeneration in mice

scientific article

Quantifying ceramide kinetics in vivo using stable isotope tracers and LC-MS/MS.

scientific article published on 6 March 2018

Regulation of MicroRNA 183 by Cyclooxygenase 2 in Liver Is DEAD-Box Helicase p68 (DDX5) Dependent: Role in Insulin Signaling.

scientific article published on 11 May 2015

Targeting a ceramide double bond improves insulin resistance and hepatic steatosis

scientific article

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