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List of works by Kamal Rahmouni

A brain leptin-renin angiotensin system interaction in the regulation of sympathetic nerve activity

scientific article

A guide to analysis of mouse energy metabolism

scientific article published on 28 December 2011

A knockin mouse model of the Bardet-Biedl syndrome 1 M390R mutation has cilia defects, ventriculomegaly, retinopathy, and obesity

scientific journal article

A leptin-BDNF pathway regulating sympathetic innervation of adipose tissue

scientific article published on 22 July 2020

A leptin-regulated circuit controls glucose mobilization during noxious stimuli

scientific article published on 17 July 2017

A mitochondrial-targeted coenzyme q analog prevents weight gain and ameliorates hepatic dysfunction in high-fat-fed mice

scientific article

Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation

scientific article published on 10 February 2011

Activation of ADAM17 (A Disintegrin and Metalloprotease 17) on Glutamatergic Neurons Selectively Promotes Sympathoexcitation

scientific article published on 01 June 2019

Adipocyte-secreted BMP8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue

scientific article published in Nature Communications

Adipose depot-specific modulation of angiotensinogen gene expression in diet-induced obesity

article

AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue

scientific article published on March 2016

Amylin acts in the central nervous system to increase sympathetic nerve activity

scientific article published on 03 May 2013

Angiotensin AT1A receptors on leptin receptor-expressing cells control resting metabolism

scientific article published on 06 March 2017

Angiotensin type 1a receptors in the forebrain subfornical organ facilitate leptin-induced weight loss through brown adipose tissue thermogenesis

scientific article published on 31 January 2015

BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions

scientific article

Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes

scientific article

Beta-adrenergic receptors are critical for weight loss but not for other metabolic adaptations to the consumption of a ketogenic diet in male mice

scientific article

Brain effects of leptin: What intracellular mechanism? ⬇️

scientific article published on December 1, 2003

Brain mineralocorticoid receptor control of blood pressure and kidney function in normotensive rats

scientific article

Brain mineralocorticoid receptors and centrally regulated functions.

scientific article

Calcium/calmodulin-dependent kinase II inhibition in smooth muscle reduces angiotensin II-induced hypertension by controlling aortic remodeling and baroreceptor function

scientific article

Cardiovascular Regulation by the Arcuate Nucleus of the Hypothalamus: Neurocircuitry and Signaling Systems

scientific article published on 4 April 2016

Cardiovascular and renal effects of central administration of a mineralocorticoid receptor antagonist in conscious female rats

scientific article published on 01 December 1999

Cardiovascular and sympathetic effects of disrupting tyrosine 985 of the leptin receptor

scientific article

Cardiovascular and sympathetic effects of leptin

scientific article

Celastrol Reduces Obesity in MC4R Deficiency and Stimulates Sympathetic Nerve Activity Affecting Metabolic and Cardiovascular Functions

scientific article published on 20 March 2019

Central PACAP mediates the sympathetic effects of leptin in a tissue-specific manner

scientific article published on 27 February 2013

Central ceramide-induced hypothalamic lipotoxicity and ER stress regulate energy balance

scientific article published on 02 October 2014

Central melanin-concentrating hormone influences liver and adipose metabolism via specific hypothalamic nuclei and efferent autonomic/JNK1 pathways

scientific article published on 6 November 2012

Chronic vagal nerve stimulation prevents high-salt diet-induced endothelial dysfunction and aortic stiffening in stroke-prone spontaneously hypertensive rats

scientific article published on 20 May 2016

Ciliopathy is differentially distributed in the brain of a Bardet-Biedl syndrome mouse model

scientific journal article

Contrasting effects of afferent and efferent vagal nerve stimulation on insulin secretion and blood glucose regulation

scientific article published on February 2016

Contrasting vascular effects caused by loss of Bardet-Biedl syndrome genes

scientific article

Corrigendum to "Differential contribution of POMC and AgRP neurons to the regulation of regional autonomic nerve activity by leptin" [Molecular Metabolism 8 (2018) 1-12].

scientific article

Differential Control of the Sympathetic Nervous System by Leptin: Implications for Obesity ⬇️

scientific article published on November 1, 2007

Differential contribution of POMC and AgRP neurons to the regulation of regional autonomic nerve activity by leptin

scientific article published on 18 December 2017

Differential effects of insulin on sympathetic nerve activity in agouti obese mice

scientific article

Direct control of brown adipose tissue thermogenesis by central nervous system glucagon-like peptide-1 receptor signaling

scientific article

Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity

scientific article published in May 2009

Does genetic variation in the leptin receptor influence the sympathetic tone in obesity?

scientific article published on 01 June 2008

ER Stress Inhibits Liver Fatty Acid Oxidation while Unmitigated Stress Leads to Anorexia-Induced Lipolysis and Both Liver and Kidney Steatosis.

scientific article published in May 2017

Ectopic expression of human BBS4 can rescue Bardet-Biedl syndrome phenotypes in Bbs4 null mice

scientific article

Editorial focus: A fat contribution to RAS activation and blood pressure control: evidence from angiotensinogen conditional null mice. Focus on: "Adipocyte-specific deficiency of angiotensinogen decreases plasma angiotensinogen concentration and sys

scientific article published on 09 November 2011

Effect of selective expression of dominant-negative PPARγ in pro-opiomelanocortin neurons on the control of energy balance

scientific article published on 13 May 2016

Effects of brain mineralocorticoid receptor blockade on blood pressure and renal functions in DOCA-salt hypertension

scientific article published in February 2002

Effects of leptin on sympathetic nerve activity in conscious mice

scientific article

Endothelial effects of leptin: implications in health and diseases

scientific article

Enhanced leptin-stimulated Pi3k activation in the CNS promotes white adipose tissue transdifferentiation

scientific article published on December 2007

Estradiol regulates brown adipose tissue thermogenesis via hypothalamic AMPK

scientific article

FGF19, FGF21, and an FGFR1/β-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia

scientific article published on 5 October 2017

FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver

scientific article published on 22 December 2015

FGF21 acts centrally to induce sympathetic nerve activity, energy expenditure, and weight loss.

scientific article

Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation.

scientific article published in November 2018

Glucose depletion in the airway surface liquid is essential for sterility of the airways

scientific article (publication date: 2011)

Hypertension-Causing Mutation in Peroxisome Proliferator-Activated Receptor γ Impairs Nuclear Export of Nuclear Factor-κB p65 in Vascular Smooth Muscle.

scientific article published on 15 May 2017

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

scientific article

Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance.

scientific article

Hypothalamic ERK mediates the anorectic and thermogenic sympathetic effects of leptin

scientific article published on 09 December 2008

Hypothalamic PI3K and MAPK differentially mediate regional sympathetic activation to insulin

scientific article published on September 2004

Hypothalamic arcuate nucleus mediates the sympathetic and arterial pressure responses to leptin

scientific article

Hypothalamic mTORC1 signaling controls sympathetic nerve activity and arterial pressure and mediates leptin effects

scientific article published on April 2013

Id3, E47, and SREBP-1c: fat factors controlling adiponectin expression

scientific article published in September 2008

Inactivation of Bardet-Biedl syndrome genes causes kidney defects

scientific article

Inflaming hypothalamic neurons raises blood pressure

scientific article published on July 2011

Influence of sodium intake on the cardiovascular and renal effects of brain mineralocorticoid receptor blockade in normotensive rats

scientific article published in September 2002

Interference with peroxisome proliferator-activated receptor-γ in vascular smooth muscle causes baroreflex impairment and autonomic dysfunction.

scientific article

Intracellular mechanisms involved in leptin regulation of sympathetic outflow

scientific article published on 16 December 2002

Intracranial Pressure Is a Determinant of Sympathetic Activity.

scientific article published on 8 February 2018

Involvement of brain mineralocorticoid receptor in salt-enhanced hypertension in spontaneously hypertensive rats

scientific article published in October 2001

Involvement of hypothalamic AMP-activated protein kinase in leptin-induced sympathetic nerve activation

scientific article

K(ATP)-channel-dependent regulation of catecholaminergic neurons controls BAT sympathetic nerve activity and energy homeostasis

scientific article published in September 2013

Lack of dilator effect of leptin in the hindlimb vascular bed of conscious rats

scientific article published in August 2005

Leptin Signaling in the Central Nervous System

Leptin and the cardiovascular system

scientific article published on January 2004

Leptin and the central neural mechanisms of obesity hypertension

article by Kamal Rahmouni & W.G. Haynes published 2002 in Medicamentos de actualidad. Drugs of today

Leptin as a Mediator of Obesity-Induced Hypertension.

scientific article published on 24 September 2016

Leptin receptor signaling in the hypothalamus regulates hepatic autonomic nerve activity via phosphatidylinositol 3-kinase and AMP-activated protein kinase

scientific article

Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome

scientific journal article

Leptin signaling in the nucleus tractus solitarii increases sympathetic nerve activity to the kidney

scientific article published on 22 December 2008

Leptin signaling pathways in the central nervous system: interactions between neuropeptide Y and melanocortins ⬇️

scientific article published on December 1, 2001

Leptin-Induced Sympathetic Nerve Activation: Signaling Mechanisms and Cardiovascular Consequences in Obesity ⬇️

scientific article published on May 1, 2010

Liver Derived FGF21 Maintains Core Body Temperature During Acute Cold Exposure

scientific article published in Scientific Reports

Liver sympathetic denervation reverses obesity-induced hepatic steatosis

scientific article published on 26 July 2019

Loss of leptin actions in obesity: two concepts with cardiovascular implications

scientific article

MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity, and Glucose Intolerance

scientific article published on 16 September 2019

Mechanisms mediating renal sympathetic activation to leptin in obesity

scientific article published on 24 September 2008

Mechanistic Target of Rapamycin Complex 1 Signaling Modulates Vascular Endothelial Function Through Reactive Oxygen Species

scientific article published on 01 May 2019

Metabolic control by S6 kinases depends on dietary lipids

scientific article (publication date: 2012)

Metabolic effects of a mitochondrial-targeted coenzyme Q analog in high fat fed obese mice

scientific article published on 10 March 2017

Metabolic rate regulation by the renin-angiotensin system: brain vs. body

scientific article published on 12 April 2012

Mkks-null mice have a phenotype resembling Bardet-Biedl syndrome

scientific journal article

Molecular basis of the obesity associated with Bardet-Biedl syndrome

scientific article

Neonatal growth restriction-related leptin deficiency enhances leptin-triggered sympathetic activation and central angiotensin II receptor-dependent stress-evoked hypertension

scientific article published on 06 April 2016

Neonatal leptin deficiency reduces frontal cortex volumes and programs adult hyperactivity in mice

scientific article published on 25 January 2014

Nervous System Expression of PPARγ and Mutant PPARγ Has Profound Effects on Metabolic Regulation and Brain Development

scientific article published on 30 August 2016

Neuroanatomical determinants of the sympathetic nerve responses evoked by leptin

scientific article published on 20 June 2012

Neuronal modulation of brown adipose activity through perturbation of white adipocyte lipogenesis

scientific article published on 27 June 2018

Neuronal receptor activity-modifying protein 1 promotes energy expenditure in mice

scientific article

Obesity, sympathetic overdrive, and hypertension: the leptin connection

scientific article published on March 2010

Obesity-associated hypertension: new insights into mechanisms.

scientific article

Obesity-associated hypertension: recent progress in deciphering the pathogenesis

scientific article

Optogenetics and pharmacogenetics: principles and applications

scientific article published on 9 August 2017

Oxidative and inflammatory signals in obesity-associated vascular abnormalities

scientific article published on 30 June 2017

PI3K signaling: A key pathway in the control of sympathetic traffic and arterial pressure by leptin

scientific article published on 23 March 2013

Prolonged treatment with angiotensin 1-7 improves endothelial function in diet-induced obesity

scientific article

Reduced renal sympathetic nerve activity contributes to elevated glycosuria and improved glucose tolerance in hypothalamus-specific Pomc knockout mice

scientific article published on 17 July 2017

Regulation of Insulin Receptor Trafficking by Bardet Biedl Syndrome Proteins

scientific article published on 23 June 2015

Regulation of glucose tolerance and sympathetic activity by MC4R signaling in the lateral hypothalamus

scientific article published on 20 January 2015

Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

scientific article

Role of leptin in the cardiovascular and endocrine complications of metabolic syndrome.

scientific article published on November 2006

Role of selective leptin resistance in diet-induced obesity hypertension.

scientific article

SF1-Specific AMPKα1 Deletion Protects Against Diet-Induced Obesity

scientific article published on 13 August 2018

SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity

scientific journal article

Selective Deletion of Renin-b in the Brain Alters Drinking and Metabolism

scientific article published on 5 September 2017

Selective Deletion of the Brain-Specific Isoform of Renin Causes Neurogenic Hypertension

scientific article

Selective leptin resistance: a new concept in leptin physiology with cardiovascular implications.

scientific article

Selective resistance to central neural administration of leptin in agouti obese mice

scientific article published in February 2002

Suppression of Resting Metabolism by the Angiotensin AT2 Receptor

scientific article published on 27 July 2016

Sympathetic inhibition after bariatric surgery

scientific article published on August 2014

Sympathetic tone in the young: the mother weighs in.

scientific article

The -20 and -217 promoter variants dominate differential angiotensinogen haplotype regulation in angiotensinogen-expressing cells

scientific article published on 2 January 2007

The Adipose/Circulating Renin-Angiotensin System Cross-Talk Enters a New Dimension ⬇️

scientific article published on October 29, 2012

The BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane

scientific article

The BBSome in POMC and AgRP Neurons Is Necessary for Body Weight Regulation and Sorting of Metabolic Receptors

scientific article published on 24 May 2019

The Bardet-Biedl syndrome protein complex regulates cell migration and tissue repair through a Cullin-3/RhoA pathway

scientific article published on 19 June 2019

The brain Renin-angiotensin system controls divergent efferent mechanisms to regulate fluid and energy balance

scientific article

The brain and brown fat

scientific article

The cellular and molecular bases of leptin and ghrelin resistance in obesity

scientific article

The central melanocortin system directly controls peripheral lipid metabolism

scientific article

The concept of selective leptin resistance: evidence from agouti yellow obese mice

scientific article published on 01 February 2002

The ion channel ASIC2 is required for baroreceptor and autonomic control of the circulation.

scientific article

The role of hypothalamic mTORC1 signaling in insulin regulation of food intake, body weight, and sympathetic nerve activity in male mice

scientific article

Three months of high-fructose feeding fails to induce excessive weight gain or leptin resistance in mice

scientific article

Traveling from the hypothalamus to the adipose tissue: The thermogenic pathway

scientific article

cAMP-inducible coactivator CRTC3 attenuates brown adipose tissue thermogenesis

scientific article published on 21 May 2018

mTORC1 Signaling Contributes to Drinking But Not Blood Pressure Responses to Brain Angiotensin II.

scientific article published on 2 June 2016

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