List of works by Christopher J Silva

A General Mass Spectrometry-Based Method of Quantitating Prion Polymorphisms from Heterozygous Chronic Wasting Disease-Infected Cervids

scientific article published on 23 December 2019

An Improved Method for the Sensitive Detection of Shiga Toxin 2 in Human Serum

scientific article published on 31 January 2018

Applying the tools of chemistry (mass spectrometry and covalent modification by small molecule reagents) to the detection of prions and the study of their structure.

scientific article published in January 2014

Assessing the role of oxidized methionine at position 213 in the formation of prions in hamsters.

scientific article published in March 2010

Available pathways database (APD): an essential resource for combinatorial biology.

scientific article

Behavioral abnormalities in prion protein knockout mice and the potential relevance of PrP(C) for the cytoskeleton

scientific article published on January 2014

Biosynthetic studies of marine lipids 36. The origin of common sterol side chains in eleven sponges using [3-3H]-squalene

scientific article published on 01 January 1992

Biosynthetic studies of marine lipids. 35. The demonstration of de novo sterol biosynthesis in sponges using radiolabeled isoprenoid precursors

scientific article published on 01 January 1991

Bovine spongiform encephalopathy

scientific article published on 01 January 2009

Covalent Surface Modification of Prions: A Mass Spectrometry-Based Means of Detecting Distinctive Structural Features of Prion Strains.

scientific article published on 19 January 2016

Determining the Relative Susceptibility of Four Prion Protein Genotypes to Atypical Scrapie

scientific article

Food Forensics: Using Mass Spectrometry To Detect Foodborne Protein Contaminants, as Exemplified by Shiga Toxin Variants and Prion Strains

scientific article published on 13 June 2018

Heterologous production of daptomycin in Streptomyces lividans.

scientific article published in November 2005

Identification of new molecular alterations in fatal familial insomnia

scientific article published on 7 April 2016

Loss of prion protein leads to age-dependent behavioral abnormalities and changes in cytoskeletal protein expression.

scientific article published on 7 March 2014

Mass Spectrometry-Based Method of Detecting and Distinguishing Type 1 and Type 2 Shiga-Like Toxins in Human Serum

scientific article

Mass spectrometric detection of attomole amounts of the prion protein by nanoLC/MS/MS.

scientific article

PK-sensitive PrP is infectious and shares basic structural features with PK-resistant PrP

scientific article

Proteinase K and the structure of PrPSc: The good, the bad and the ugly

scientific article published on 24 March 2015

Quantitating PrP Polymorphisms Present in Prions from Heterozygous Scrapie-Infected Sheep.

scientific article

Recombinant PrPSc shares structural features with brain-derived PrPSc: Insights from limited proteolysis.

scientific article published on 31 January 2018

Safe and effective means of detecting and quantitating Shiga-like toxins in attomole amounts

scientific article published on 2 May 2014

Sensitive, preclinical detection of prions in brain by nanospray liquid chromatography/tandem mass spectrometry.

scientific article published in January 2007

Squalene synthase-deficient mutant of Chinese hamster ovary cells ⬇️

scientific article published on September 15, 1992

Structural organization of mammalian prions as probed by limited proteolysis

scientific article

Using Nanospray Liquid Chromatography and Mass Spectrometry to Quantitate Shiga Toxin Production in Environmental Escherichia coli Recovered from a Major Produce Production Region in California

scientific article published on 21 December 2018

Using small molecule reagents to selectively modify epitopes based on their conformation.

scientific article

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