List of works - Yasushi Sako

A RasGTP-induced conformational change in C-RAF is essential for accurate molecular recognition

scientific article published in September 2009

A Role for the Anti-Viral Host Defense Mechanism in the Phylogenetic Divergence in Baculovirus Evolution

scientific article published on 31 May 2016

A bipolar functionality of Q/N-rich proteins: Lsm4 amyloid causes clearance of yeast prions.

scientific article published on 20 March 2013

A novel sphingomyelin/cholesterol domain-specific probe reveals the dynamics of the membrane domains during virus release and in Niemann-Pick type C

scientific article

Assembly of protein complexes restricts diffusion of Wnt3a proteins

scientific article published on 10 October 2018

Cell surface organization by the membrane skeleton.

scientific article published on August 1996

Characterization of the triplet state of hybridization-sensitive DNA probe by using fluorescence correlation spectroscopy

scientific article published on 21 December 2012

Comparison of two-photon excitation laser scanning microscopy with UV-confocal laser scanning microscopy in three-dimensional calcium imaging using the fluorescence indicator Indo-1.

scientific article published on January 1997

Conversion of graded phosphorylation into switch-like nuclear translocation via autoregulatory mechanisms in ERK signalling.

scientific article published on 20 January 2016

Cortical Polarity of the RING Protein PAR-2 Is Maintained by Exchange Rate Kinetics at the Cortical-Cytoplasmic Boundary.

scientific article published on 10 August 2016

Cortical Polarity of the RING Protein PAR-2 Is Maintained by Exchange Rate Kinetics at the Cortical-Cytoplasmic Boundary.

scientific article published in September 2016

Covalent immobilization of epidermal growth factor molecules for single-molecule imaging analysis of intracellular signaling

scientific article published on 24 February 2006

Cytoplasmic regulation of the movement of E-cadherin on the free cell surface as studied by optical tweezers and single particle tracking: corralling and tethering by the membrane skeleton.

scientific article published on March 1998

Dynamic and unique nucleolar microenvironment revealed by fluorescence correlation spectroscopy.

scientific article published on 17 November 2014

Dynamically varying interactions between heregulin and ErbB proteins detected by single-molecule analysis in living cells

scientific article

EGF signalling amplification induced by dynamic clustering of EGFR.

scientific article

Engagement of CD44 promotes Rac activation and CD44 cleavage during tumor cell migration.

scientific article

Enhanced transcriptional heterogeneity mediated by NF-κB super-enhancers

scientific article published on 01 June 2022

Epidermal growth factor-regulated activation of Rac GTPase enhances CD44 cleavage by metalloproteinase disintegrin ADAM10.

scientific article published on April 2006

Formation of signal transduction complexes during immobile phase of NGFR movements

scientific article published on 03 February 2006

Imaging single molecules in living cells for systems biology

scientific article

Interaction of a novel fluorescent GTP analogue with the small G-protein K-Ras.

scientific article published on 15 July 2015

Local nucleosome dynamics facilitate chromatin accessibility in living mammalian cells.

scientific article published on 13 December 2012

Multiple mechanisms for accumulation of myosin II filaments at the equator during cytokinesis.

scientific article published on 25 September 2008

Multiple-state reactions between the epidermal growth factor receptor and Grb2 as observed by using single-molecule analysis.

scientific article

Non-Markovian properties and multiscale hidden Markovian network buried in single molecule time series.

scientific article published in December 2013

Optical bioimaging: from living tissue to a single molecule: single-molecule visualization of cell signaling processes of epidermal growth factor receptor.

scientific article published on November 2003

Optimality conditions for cell-fate heterogeneity that maximize the effects of growth factors in PC12 cells

scientific article

Origin of the low thermal isomerization rate of rhodopsin chromophore

scientific article published on 10 June 2015

Photosystem II antenna phosphorylation-dependent protein diffusion determined by fluorescence correlation spectroscopy

scientific article published on 03 October 2013

Positive feedback within a kinase signaling complex functions as a switch mechanism for NF-κB activation

scientific article published on May 2014

Power law relationship between cell cycle duration and cell volume in the early embryonic development of Caenorhabditis elegans

scientific article

Quantitative live-cell imaging reveals spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome

scientific article published on 6 March 2014

Raman spectral dynamics of single cells in the early stages of growth factor stimulation

scientific article published on May 2015

Reduction-triggered fluorescent amplification probe for the detection of endogenous RNAs in living human cells.

scientific article published in May 2009

Regulation mechanism of the lateral diffusion of band 3 in erythrocyte membranes by the membrane skeleton.

scientific article published on August 1998

Rolling circle amplification in a prokaryotic translation system using small circular RNA.

scientific article

SEIBUTSU BUTSURI, the official Japanese journal of the Biophysical Society of Japan

scientific article published on 29 January 2020

Single- and multiple-molecule dynamics of the signaling from H-Ras to cRaf-1 visualized on the plasma membrane of living cells.

scientific article published in July 2003

Single-molecule analysis of chemotactic signaling in Dictyostelium cells.

scientific article

Single-molecule analysis of epidermal growth factor binding on the surface of living cells.

scientific article

Single-molecule diffusion-based estimation of ligand effects on G protein-coupled receptors

scientific article published on 18 September 2018

Single-molecule fluorescence-based analysis of protein conformation, interaction, and oligomerization in cellular systems

scientific article

Single-molecule observation of the ligand-induced population shift of rhodopsin, a G-protein-coupled receptor.

scientific article published on February 2014

State transition analysis of spontaneous branch migration of the Holliday junction by photon-based single-molecule fluorescence resonance energy transfer

scientific article published on 2 December 2015

Total internal reflection fluorescence microscopy for single-molecule imaging in living cells.

scientific article

Trafficking of a ligand-receptor complex on the growth cones as an essential step for the uptake of nerve growth factor at the distal end of the axon: a single-molecule analysis

scientific article published on 01 March 2005

Universal caging group for the in-cell detection of glutathione transferase applied to 19F NMR and bioluminogenic probes.

scientific article published on 11 June 2012

Variational Bayes analysis of a photon-based hidden Markov model for single-molecule FRET trajectories

scientific article

Visualizing specific protein glycoforms by transmembrane fluorescence resonance energy transfer

scientific article published on 19 June 2012

[PSI(+)] aggregate enlargement in rnq1 nonprion domain mutants, leading to a loss of prion in yeast.

scientific article published in April 2011

List of works by Yasushi Sako

A RasGTP-induced conformational change in C-RAF is essential for accurate molecular recognition

A Role for the Anti-Viral Host Defense Mechanism in the Phylogenetic Divergence in Baculovirus Evolution

A bipolar functionality of Q/N-rich proteins: Lsm4 amyloid causes clearance of yeast prions.

A novel sphingomyelin/cholesterol domain-specific probe reveals the dynamics of the membrane domains during virus release and in Niemann-Pick type C

Assembly of protein complexes restricts diffusion of Wnt3a proteins

Cell surface organization by the membrane skeleton.

Characterization of the triplet state of hybridization-sensitive DNA probe by using fluorescence correlation spectroscopy

Comparison of two-photon excitation laser scanning microscopy with UV-confocal laser scanning microscopy in three-dimensional calcium imaging using the fluorescence indicator Indo-1.

Conversion of graded phosphorylation into switch-like nuclear translocation via autoregulatory mechanisms in ERK signalling.

Cortical Polarity of the RING Protein PAR-2 Is Maintained by Exchange Rate Kinetics at the Cortical-Cytoplasmic Boundary.

Cortical Polarity of the RING Protein PAR-2 Is Maintained by Exchange Rate Kinetics at the Cortical-Cytoplasmic Boundary.

Covalent immobilization of epidermal growth factor molecules for single-molecule imaging analysis of intracellular signaling

Cytoplasmic regulation of the movement of E-cadherin on the free cell surface as studied by optical tweezers and single particle tracking: corralling and tethering by the membrane skeleton.

Dynamic and unique nucleolar microenvironment revealed by fluorescence correlation spectroscopy.

Dynamically varying interactions between heregulin and ErbB proteins detected by single-molecule analysis in living cells

EGF signalling amplification induced by dynamic clustering of EGFR.

Engagement of CD44 promotes Rac activation and CD44 cleavage during tumor cell migration.

Enhanced transcriptional heterogeneity mediated by NF-κB super-enhancers

Epidermal growth factor-regulated activation of Rac GTPase enhances CD44 cleavage by metalloproteinase disintegrin ADAM10.

Formation of signal transduction complexes during immobile phase of NGFR movements

Imaging single molecules in living cells for systems biology

Interaction of a novel fluorescent GTP analogue with the small G-protein K-Ras.

Local nucleosome dynamics facilitate chromatin accessibility in living mammalian cells.

Multiple mechanisms for accumulation of myosin II filaments at the equator during cytokinesis.

Multiple-state reactions between the epidermal growth factor receptor and Grb2 as observed by using single-molecule analysis.

Non-Markovian properties and multiscale hidden Markovian network buried in single molecule time series.

Optical bioimaging: from living tissue to a single molecule: single-molecule visualization of cell signaling processes of epidermal growth factor receptor.

Optimality conditions for cell-fate heterogeneity that maximize the effects of growth factors in PC12 cells

Origin of the low thermal isomerization rate of rhodopsin chromophore

Photosystem II antenna phosphorylation-dependent protein diffusion determined by fluorescence correlation spectroscopy

Positive feedback within a kinase signaling complex functions as a switch mechanism for NF-κB activation

Power law relationship between cell cycle duration and cell volume in the early embryonic development of Caenorhabditis elegans

Quantitative live-cell imaging reveals spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome

Raman spectral dynamics of single cells in the early stages of growth factor stimulation

Reduction-triggered fluorescent amplification probe for the detection of endogenous RNAs in living human cells.

Regulation mechanism of the lateral diffusion of band 3 in erythrocyte membranes by the membrane skeleton.

Rolling circle amplification in a prokaryotic translation system using small circular RNA.

SEIBUTSU BUTSURI, the official Japanese journal of the Biophysical Society of Japan

Single- and multiple-molecule dynamics of the signaling from H-Ras to cRaf-1 visualized on the plasma membrane of living cells.

Single-molecule analysis of chemotactic signaling in Dictyostelium cells.

Single-molecule analysis of epidermal growth factor binding on the surface of living cells.

Single-molecule diffusion-based estimation of ligand effects on G protein-coupled receptors

Single-molecule fluorescence-based analysis of protein conformation, interaction, and oligomerization in cellular systems

Single-molecule observation of the ligand-induced population shift of rhodopsin, a G-protein-coupled receptor.

State transition analysis of spontaneous branch migration of the Holliday junction by photon-based single-molecule fluorescence resonance energy transfer

Total internal reflection fluorescence microscopy for single-molecule imaging in living cells.

Trafficking of a ligand-receptor complex on the growth cones as an essential step for the uptake of nerve growth factor at the distal end of the axon: a single-molecule analysis

Universal caging group for the in-cell detection of glutathione transferase applied to 19F NMR and bioluminogenic probes.

Variational Bayes analysis of a photon-based hidden Markov model for single-molecule FRET trajectories

Visualizing specific protein glycoforms by transmembrane fluorescence resonance energy transfer

[PSI(+)] aggregate enlargement in rnq1 nonprion domain mutants, leading to a loss of prion in yeast.