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List of works by Mauro Giacca

A Candidate Approach Implicates the Secreted Salmonella Effector Protein SpvB in P-Body Disassembly ⬇️

scientific article published on March 1, 2011

A human DNA replication origin: localization and transcriptional characterization

scientific article published on January 1, 1992

A human binding site for transcription factor USF/MLTF mimics the negative regulatory element of human immunodeficiency virus type 1.

scientific article

A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration

scientific article published on 10 August 2021

A mouse model for adult cardiac-specific gene deletion with CRISPR/Cas9

scientific article

A new dual-promoter system for cardiomyocyte-specific conditional induction of apoptosis

scientific article published on 31 January 2013

A new locus for arrhythmogenic right ventricular dysplasia on the long arm of chromosome 14.

scientific article

A novel animal model to study non-spontaneous bisphosphonates osteonecrosis of jaw.

scientific article published on 28 February 2010

A novel myogenic cell line with phenotypic properties of muscle progenitors

scientific article published on 24 October 2007

A novel procedure for quantitative polymerase chain reaction by coamplification of competitive templates

scientific article published on 01 December 1992

A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent

scientific article published on 01 May 2018

AAV vector encoding human VEGF165-transduced pectineus muscular flaps increase the formation of new tissue through induction of angiogenesis in an in vivo chamber for tissue engineering: A technique to enhance tissue and vessels in microsurgically e

scientific article published on January 2015

AAV-mediated gene transfer of tissue inhibitor of metalloproteinases-1 inhibits vascular tumor growth and angiogenesis in vivo

scientific article published on January 2004

AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia

scientific article published on 11 June 2015

AAV9-mediated Rbm24 overexpression induces fibrosis in the mouse heart

scientific article published in Scientific Reports

AAV9-mediated functional screening for cardioprotective cytokines in Coxsackievirus-B3-induced myocarditis

scientific article published in 2022

ADVANCES IN MOLECULAR GENETICS OF DILATED CARDIOMYOPATHY

article

Acetylation by GCN5 regulates CDC6 phosphorylation in the S phase of the cell cycle.

scientific article published on 3 April 2009

Acetylation of HIV-1 integrase by p300 regulates viral integration

scientific article

Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription

scientific article

Acylated ghrelin treatment normalizes skeletal muscle mitochondrial oxidative capacity and AKT phosphorylation in rat chronic heart failure

scientific article published on 3 November 2017

Adeno-associated virus vectors as therapeutic and investigational tools in the cardiovascular system

scientific article (publication date: 23 May 2014)

Adeno-associated virus vectors: versatile tools for in vivo gene transfer.

scientific article published on January 2008

Adeno-associated virus-mediated CTLA4Ig gene transfer protects MHC-mismatched renal allografts from chronic rejection

scientific article published on 26 April 2006

Adeno-associated virus-mediated transduction of VEGF165 improves cardiac tissue viability and functional recovery after permanent coronary occlusion in conscious dogs.

scientific article

Adipokines, ghrelin and obesity-associated insulin resistance in nondiabetic patients with acute coronary syndrome

scientific article published on 04 May 2012

Amino acid modification in the HIV-1 Tat basic domain: insights from molecular dynamics and in vivo functional studies.

scientific article published in May 2002

An Animal Model to Study Bisphosphonates Associated Osteonecrosis of the Jaw ⬇️

scholarly article

An integrative translational approach to study heart failure with preserved ejection fraction: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology

scientific article published on 16 November 2017

Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression

scientific article published on 01 June 2008

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

scientific article published in 2022

Anti-Fungal Drug Anidulafungin Inhibits SARS-CoV-2 Spike-Induced Syncytia Formation by Targeting ACE2-Spike Protein Interaction

scientific article published on 25 March 2022

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

scientific article

Anti-idiotypic response in mice expressing human autoantibodies.

scientific article published on 8 November 2007

Arteriogenic therapy based on simultaneous delivery of VEGF-A and FGF4 genes improves the recovery from acute limb ischemia

scientific article

Association between mutation status and left ventricular reverse remodelling in dilated cardiomyopathy.

scientific article published on 17 April 2017

Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis in mice.

scientific article published on June 2008

Bone marrow mononuclear cells are recruited to the sites of VEGF-induced neovascularization but are not incorporated into the newly formed vessels.

scientific article published on 3 January 2006

Boosting anti-idiotype immune response with recombinant AAV enhances tumour protection induced by gene gun vaccination.

scientific article published on 12 May 2008

Brain delivery of AAV9 expressing an anti-PrP monovalent antibody delays prion disease in mice.

scientific article

C-C chemokines released by lipopolysaccharide (LPS)-stimulated human macrophages suppress HIV-1 infection in both macrophages and T cells.

scientific article published on March 1997

CRISPR-Csy4-Mediated Editing of Rotavirus Double-Stranded RNA Genome

scientific article published on 01 September 2020

Capsid protein expression and adeno-associated virus like particles assembly in Saccharomyces cerevisiae ⬇️

scientific article published on September 11, 2012

Carbon nanotubes instruct physiological growth and functionally mature syncytia: nongenetic engineering of cardiac myocytes

scientific article

Carbon nanotubes promote growth and spontaneous electrical activity in cultured cardiac myocytes

scientific article published on 28 March 2012

Cardiac Regeneration After Myocardial Infarction: an Approachable Goal

scientific article published on 10 August 2020

Cardiac dysfunction in cancer patients: beyond direct cardiomyocyte damage of anticancer drugs. Novel cardio-oncology insights from the joint 2019 meeting of the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart

scientific article published on 19 July 2020

Cardiac regeneration and remodelling of the cardiomyocyte cytoarchitecture

scientific article published on 06 December 2019

Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction.

scientific article published on 17 December 2009

Cardiomyocytes stimulate angiogenesis after ischemic injury in a ZEB2-dependent manner

scientific article published on 04 January 2021

Cell cycle modulation of protein-DNA interactions at a human replication origin ⬇️

scientific article published on May 15, 1998

Cell surface-associated Tat modulates HIV-1 infection and spreading through a specific interaction with gp120 viral envelope protein

scientific article

Cellular TRIM33 restrains HIV-1 infection by targeting viral integrase for proteasomal degradation

article

Changes in thymic function in HIV-positive patients treated with highly active antiretroviral therapy and interleukin-2

scientific article published on 01 September 2001

Chapter 20: Gene therapy perspectives for nerve repair

scientific article published on January 2009

Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material

scientific article

Cluster analysis of antibiotic susceptibility patterns of clinical isolates as a tool in nosocomial infection surveillance.

scientific article

Coherent Dynamics of Photoexcited Green Fluorescent Proteins

scientific article published in Physical Review Letters

Common Regulatory Pathways Mediate Activity of MicroRNAs Inducing Cardiomyocyte Proliferation.

scientific article

Competitive PCR for precise nucleic acid quantification.

scientific article published in January 2007

Concerted action of cellular JNK and Pin1 restricts HIV-1 genome integration to activated CD4+ T lymphocytes.

scientific article published on 21 February 2010

Coupling AAV-mediated promoterless gene targeting to SaCas9 nuclease to efficiently correct liver metabolic diseases

scientific article published on 18 June 2019

Crucial role of nuclear factor-kappaB in neointimal hyperplasia of the mouse carotid artery after interruption of blood flow.

scientific article published in February 2003

DNA loop anchorage region colocalizes with the replication origin located downstream to the human gene encoding lamin B2

scientific article published on 01 April 1998

DNA-protein interaction dynamics at the Lamin B2 replication origin

scientific article

Deferoxamine mesylate improves splicing and GAA activity of the common c.-32-13T>G allele in late-onset PD patient fibroblasts

scientific article published on 20 November 2020

Detection of c-erbB-2 amplification in transitional cell bladder carcinoma using competitive PCR technique

scientific article published on 01 December 1996

Detection of human immunodeficiency virus type 1 genomic RNA in plasma samples by reverse-transcription polymerase chain reaction ⬇️

scientific article published on June 1, 1991

Development of antibody fragments for immunotherapy of prion diseases

scientific article published in March 2009

Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat.

scientific article published in January 2002

Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia

scientific article

Dynamics of Provirus Load and Lymphocyte Subsets after Interleukin 2 Treatment in HIV-Infected Patients

article

Dynamics of hypervariable region 1 variation in hepatitis C virus infection and correlation with clinical and virological features of liver disease.

scientific article published on June 1998

E2F Family Members Are Differentially Regulated by Reversible Acetylation

scientific article published in Journal of Biological Chemistry

Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression

scientific article

Effect of class IV laser therapy on chemotherapy-induced oral mucositis: a clinical and experimental study.

scientific article

Effect of recombinant adeno-associated virus vector-mediated vascular endothelial growth factor gene transfer on wound healing after burn injury

scientific article published in April 2003

Effect of vascular endothelial growth factor gene therapy on post-traumatic peripheral nerve regeneration and denervation-related muscle atrophy ⬇️

scientific article published on May 30, 2013

Endothelial cell-cardiomyocyte crosstalk in heart development and disease

scientific article published on 28 February 2019

Engineered Green Fluorescence Proteins for Proteomics and Biomolecular Electronic Applications

Enhanced athletic performance on multisite AAV-IGF1 gene transfer coincides with massive modification of the muscle proteome

scientific article published on 26 January 2012

Enhanced caveolae-mediated endocytosis by diagnostic ultrasound in vitro

scientific article

Enhancement of expression of vascular endothelial growth factor after adeno-associated virus gene transfer is associated with improvement of brain ischemia injury in the gerbil.

scientific article published in September 2003

Epigenetic modification at Notch responsive promoters blunts efficacy of inducing notch pathway reactivation after myocardial infarction.

scientific article published on 11 August 2014

Epigenetic silencing of miR-296 and miR-512 ensures hTERT dependent apoptosis protection and telomere maintenance in basal-type breast cancer cells.

scientific article published on 23 September 2017

Evaluation of nutritional status in head and neck radio-treated patients affected by oral mucositis: efficacy of class IV laser therapy.

scientific article

Expression of BCL-2 via adeno-associated virus vectors rescues thalamic neurons after visual cortex lesion in the adult rat.

scientific article

Expression profiling of angiogenic genes for the characterisation of colorectal carcinoma.

scientific article published on 23 July 2008

Extra- and intracellular factors regulating cardiomyocyte proliferation in postnatal life.

scientific article published on 12 March 2014

Extracellular HIV-1 Tat protein differentially activates the JNK and ERK/MAPK pathways in CD4 T cells

article

Familial dilated cardiomyopathy

scientific article published on 01 July 1999

Fine mapping of a replication origin of human DNA.

scientific article published on July 1994

Fruit-specific expression of the human immunodeficiency virus type 1 tat gene in tomato plants and its immunogenic potential in mice.

scientific article

Functional high-throughput screening identifies the miR-15 microRNA family as cellular restriction factors for Salmonella infection

scientific article published on 22 August 2014

Functional properties of the separate subunits of human DNA helicase II/Ku autoantigen

scientific article published on 01 November 1997

Functional screening identifies miRNAs inducing cardiac regeneration.

scientific article

Functional screenings reveal different requirements for host microRNAs in Salmonella and Shigella infection

scientific article published on 02 December 2019

Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease

article

Fusion of the human immunodeficiency virus type 1 tat protein transduction domain to thymidine kinase increases bystander effect and induces enhanced tumor killing in vivo

scientific article

GCN5-dependent acetylation of HIV-1 integrase enhances viral integration

scientific article published on 12 March 2010

GCN5-dependent acetylation of HIV-1 integrase enhances viral integration.

scientific article published on 24 September 2009

Gene Therapy With Angiotensin-(1-9) Preserves Left Ventricular Systolic Function After Myocardial Infarction

scientific article published on December 2016

Gene Therapy for the Heart Lessons Learned and Future Perspectives

scientific article published on 07 May 2020

Gene looping between the viral LTRs is a hallmark of transcriptionally active HIV-1 and Mo-MLV proviral DNA

article

Gene therapy to induce cellular resistance to HIV-1 infection: lessons from clinical trials.

scientific article published on January 2008

Gene transfer of IkappaBalpha limits infarct size in a mouse model of myocardial ischemia-reperfusion injury.

scientific article published in August 2003

Genetic lineage tracing reveals poor angiogenic potential of cardiac endothelial cells

scientific article published on 30 January 2020

Genetic polymorphisms of the renin-angiotensin-aldosterone system and renal insufficiency in essential hypertension

scientific article published in February 2005

Genome-wide RNAi screening identifies host restriction factors critical for in vivo AAV transduction

scientific article

Genome-wide mapping of human DNA-replication origins: levels of transcription at ORC1 sites regulate origin selection and replication timing.

scientific article published on 27 November 2012

Ground control to Major Tom: "prepare for HIV landing".

scientific article published on 12 November 2014

HIV Tat, its TARgets and the control of viral gene expression

scientific article

HIV-1 Tat Binding to PCAF Bromodomain: Structural Determinants from Computational Methods

scientific article

HIV-1 Tat, apoptosis and the mitochondria: a tubulin link?

scientific article

HIV-1 acetylated integrase is targeted by KAP1 (TRIM28) to inhibit viral integration.

scientific article published on 24 September 2009

HIV-1 integrase binding to its cellular partners: a perspective from computational biology

scientific article published on January 2014

HPV-16 virions can remain infectious for 2 weeks on senescent cells but require cell cycle re-activation to allow virus entry

scientific article published on 16 January 2018

Harnessing the microRNA pathway for cardiac regeneration.

scientific article published on 29 September 2015

Heartening results: the CUPID gene therapy trial for heart failure.

scientific article published on July 2011

High-content screen in human pluripotent cells identifies miRNA-regulated pathways controlling pluripotency and differentiation

scientific article published on 08 July 2019

High-throughput screening discovers antifibrotic properties of haloperidol by hindering myofibroblast activation

scientific article published on 18 April 2019

Human chorionic gonadotropin in the treatment of HIV-related Kaposi's sarcoma

scientific article published on 01 September 1998

Human origins of DNA replication selected from a library of nascent DNA.

scientific article published in August 2005

Human synaptobrevin-like 1 gene basal transcription is regulated through the interaction of selenocysteine tRNA gene transcription activating factor-zinc finger 143 factors with evolutionary conserved cis-elements

scientific article (publication date: 27 February 2004)

Id genes are essential for early heart formation

scientific article published on 9 August 2017

Identification of HSP90 inhibitors as a novel class of senolytics.

scientific article published on 4 September 2017

Idiopathic dilated cardiomyopathy and persistent viral infection: lack of association in a controlled study using a quantitative assay.

scientific article

Imaging HIV-1 nuclear pre-integration complexes

scientific article published on January 2014

Immobilized HIV-1 Tat protein promotes gene transfer via a transactivation-independent mechanism which requires binding of Tat to viral particles

scientific article

Improved survival of ischemic cutaneous and musculocutaneous flaps after vascular endothelial growth factor gene transfer using adeno-associated virus vectors

scientific article

Improved survival of rat ischemic cutaneous and musculocutaneous flaps after VEGF gene transfer.

scientific article published in January 2007

In Vivo Functional Selection Identifies Cardiotrophin-1 as a Cardiac Engraftment Factor for Mesenchymal Stromal Cells

scientific article

In vitro selection of HIV-1 TAR variants by the Tat protein ⬇️

scientific article published on April 15, 1998

In vivo activation of a conserved microRNA program induces mammalian heart regeneration

scientific article published on 6 November 2014

In vivo imaging shows abnormal function of vascular endothelial growth factor-induced vasculature

scientific article published in June 2007

In vivo selection of novel biotherapeutics

scientific article published on 22 August 2015

In vivo therapeutic potential of mesenchymal stromal cells depends on the source and the isolation procedure.

scientific article

In vivo transfer and expression of genes coding for short interfering RNAs.

scientific article published in August 2004

Inducible adeno-associated virus vectors promote functional angiogenesis in adult organisms via regulated vascular endothelial growth factor expression.

scientific article published on 14 May 2009

Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors.

scientific article published in April 2003

Inhibition of Non Canonical HIV-1 Tat Secretion Through the Cellular Na+,K+-ATPase Blocks HIV-1 Infection

scientific article published on 13 June 2017

Inhibition of choroidal and corneal pathologic neovascularization by Plgf1-de gene transfer.

scientific article

Insights on HIV-1 Tat:P/CAF bromodomain molecular recognition from in vivo experiments and molecular dynamics simulations.

scientific article

Insulin downregulates SIRT1 and AMPK activation and is associated with changes in liver fat, but not in inflammation and mitochondrial oxidative capacity, in streptozotocin-diabetic rat

scientific article published on 24 November 2010

Integration site selection by retroviruses

scientific article published on January 2004

Interaction of HIV-1 Tat protein with heparin. Role of the backbone structure, sulfation, and size

scientific article (publication date: 25 April 1997)

Interaction of the retinoblastoma protein with Orc1 and its recruitment to human origins of DNA replication

scientific article

Intracoronary Cytoprotective Gene Therapy: A Study of VEGF-B167 in a Pre-Clinical Animal Model of Dilated Cardiomyopathy

scientific article published in July 2015

Intracoronary Gene Delivery of the Cytoprotective Factor Vascular Endothelial Growth Factor-B in Canine Patients with Dilated Cardiomyopathy: A Short-Term Feasibility Study

article

Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy

scientific article published on 29 April 2010

Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling

scientific journal article

Involvement of cellular double-stranded DNA break binding proteins in processing of the recombinant adeno-associated virus genome.

scientific article

Knockdown of cyclin-dependent kinase inhibitors induces cardiomyocyte re-entry in the cell cycle

scientific article

Lack of detectable human T-cell lymphotropic virus type I sequences in samples from multiple sclerosis patients

scientific article published on March 1, 1992

Laser Therapy Inhibits Tumor Growth in Mice by Promoting Immune Surveillance and Vessel Normalization.

scientific article

Lemur tyrosine kinase 2 (LMTK2) is a determinant of cell sensitivity to apoptosis by regulating the levels of the BCL2 family members

scientific article published on 28 December 2016

Local delivery of the Neuregulin1 receptor ecto-domain (ecto-ErbB4) has a positive effect on regenerated nerve fiber maturation

scientific article published on 4 May 2015

Low frequency of detection by nested polymerase chain reaction of enterovirus ribonucleic acid in endomyocardial tissue of patients with idiopathic dilated cardiomyopathy

scientific article published on 01 October 1994

MIB2 variants altering NOTCH signalling result in left ventricle hypertrabeculation/non-compaction and are associated with Ménétrier-like gastropathy

scientific article published on 23 December 2016

Macrophage microRNA-155 promotes cardiac hypertrophy and failure.

scientific article published on 16 August 2013

Manufacturing and characterization of a recombinant adeno-associated virus type 8 reference standard material.

scientific article

Mapping Replication Origins by Quantifying Relative Abundance of Nascent DNA Strands Using Competitive Polymerase Chain Reaction ⬇️

scientific article published on November 1, 1997

Meeting highlights from the 2013 European Society of Cardiology Heart Failure Association Winter Meeting on Translational Heart Failure Research

scientific article published on 14 December 2013

MiR-16 regulates the pro-tumorigenic potential of lung fibroblasts through the inhibition of HGF production in an FGFR-1- and MEK1-dependent manner

scientific article published on 20 March 2018

MiR-320a as a Potential Novel Circulating Biomarker of Arrhythmogenic CardioMyopathy.

scientific article

MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors

scientific article

MicroRNA hsa-miR-29a-3p is a plasma biomarker for the differential diagnosis and monitoring of tuberculosis

scientific article published on 06 December 2018

MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs

scientific article published on 08 May 2019

Microsurgical arterovenous loops and biological templates: a novel in vivo chamber for tissue engineering.

scientific article

Modular structure of the human lamin B2 replicator

scientific article published on April 2004

Molecular regulation of protein catabolism in trauma patients

scientific article published on 01 April 1999

Multi-Investigator Letter on Reproducibility of Neonatal Heart Regeneration following Apical Resection

Multi-investigator letter on reproducibility of neonatal heart regeneration following apical resection

scientific article

Multiple interactions of HIV-I Tat protein with size-defined heparin oligosaccharides

scientific article (publication date: October 1999)

Multivariate analysis of antibiograms for typing Pseudomonas aeruginosa.

scientific article published in October 1987

NEUROD1 Instructs Neuronal Conversion in Non-Reactive Astrocytes

scientific article

Nanoparticles from lipid-based liquid crystals: emulsifier influence on morphology and cytotoxicity.

scientific article

Naturally C-Terminally truncated STAT5 (STAT5Δ): a novel negative controller of HIV-1 transcription and expression

article

Naturally occurring C-terminally truncated STAT5 is a negative regulator of HIV-1 expression

scientific article published on March 2007

Negative regulation of HIV-1 transcription by a heterodimeric NF-κB1/p50 and C-terminally truncated STAT5 complex

scientific article published in July 2011

Nerve growth factor gene therapy using adeno-associated viral vectors prevents cardiomyopathy in type 1 diabetic mice

scientific article published on January 2012

Neuronal hemoglobin affects dopaminergic cells' response to stress

scientific article published on 05 January 2017

Neuropilin-1 identifies a subset of bone marrow Gr1- monocytes that can induce tumor vessel normalization and inhibit tumor growth

scientific article published on 7 December 2012

Non-coding RNA therapeutics for cardiac regeneration

scientific article published on 26 March 2020

Non-coding RNAs - Update on mechanisms and therapeutic targets from the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart

scientific article published on 08 July 2020

Non-redundant functions of the protein isoforms arising from alternative splicing of the VEGF-A pre-mRNA ⬇️

scientific article published on August 3, 2010

Notch pathway activation enhances cardiosphere in vitro expansion

scholarly article by Ilaria Secco et al published November 2018 in Journal of Cellular and Molecular Medicine

Notch1 activity in the olfactory bulb is odour-dependent and contributes to olfactory behaviour.

scientific article published on 19 September 2014

Notch1 signaling stimulates proliferation of immature cardiomyocytes

scientific journal article

Novel and unexpected cellular partners for HIV-1 integrase and Tat

article

Novel human-derived cell-penetrating peptides for specific subcellular delivery of therapeutic biomolecules

scientific article

Nuclear architecture dictates HIV-1 integration site selection.

scientific article

Nuclear organization and the control of HIV-1 transcription

scientific article published on February 2004

Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction.

scientific article published on 26 June 2018

Pathways for salvage and protection of the heart under stress: novel routes for cardiac rejuvenation.

scientific article

Pentraxin 3 inhibits fibroblast growth factor 2-dependent activation of smooth muscle cells in vitro and neointima formation in vivo

scientific article published on 14 July 2005

Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology

scientific article published on 30 October 2020

Persistence of viral RNA, widespread thrombosis and abnormal cellular syncytia are hallmarks of COVID-19 lung pathology

scientific article published on 26 June 2020

Persistent <scp>SARS‐CoV</scp>‐2 infection in patients seemingly recovered from <scp>COVID</scp>‐19

scientific article published in 2023

Postnatal Cardiac Gene-Editing Using CRISPR/Cas9 with AAV9-Mediated Delivery of Short Guide RNAs Results in Mosaic Gene Disruption.

scientific article

Potent inhibition of arterial intimal hyperplasia by TIMP1 gene transfer using AAV vectors

scientific article published in June 2004

Presence of transcription signals in two putative DNA replication origins of human cells

scientific article published on 01 December 1988

Preserved Skeletal Muscle Mitochondrial Function, Redox State, Inflammation and Mass in Obese Mice with Chronic Heart Failure

scientific article published on 04 November 2020

Processing of recombinant AAV genomes occurs in specific nuclear structures that overlap with foci of DNA-damage-response proteins.

scientific article published on February 2008

Proliferation of Multiple Cell Types in the Skeletal Muscle Tissue Elicited by Acute p21 Suppression

scientific article published on 11 February 2015

Proximity to PML nuclear bodies regulates HIV-1 latency in CD4+ T cells.

scientific article published in June 2013

Quantitative analysis of hepatitis C virus RNA in liver biopsies by competitive reverse transcription and polymerase chain reaction.

scientific article published on October 1995

RNA mimics as therapeutics for cardiac regeneration: a paradigm shift

scientific article published on June 2015

Reactivating endogenous mechanisms of cardiac regeneration via paracrine boosting using the human amniotic fluid stem cell secretome

scientific article published on 04 April 2019

Recombinant AAV vector encoding human VEGF165 enhances wound healing.

scientific article

Recruitment of human cyclin T1 to nuclear bodies through direct interaction with the PML protein

scientific article

Regenerative potential of epicardium-derived extracellular vesicles mediated by conserved miRNA transfer

scientific article published on 01 January 2022

Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter

scientific article

Regulation of HIV-1 latency by chromatin structure and nuclear architecture.

scientific article

Regulation of adeno-associated virus DNA replication by the cellular TAF-I/set complex

scientific article published on July 2006

Repeated AAV-mediated gene transfer by serotype switching enables long-lasting therapeutic levels of hUgt1a1 enzyme in a mouse model of Crigler-Najjar Syndrome Type I.

scientific article published on 14 August 2017

Rescue of bilirubin‐induced neonatal lethality in a mouse model of Crigler‐Najjar syndrome type I by AAV9‐mediated gene transfer ⬇️

scientific article published on November 17, 2011

Reversible Notch1 acetylation tunes proliferative signalling in cardiomyocytes

scientific article published on 24 November 2017

Reversible acetylation regulates vascular endothelial growth factor receptor-2 activity

scientific article

Ribozyme-mediated inhibition of survivin expression increases spontaneous and drug-induced apoptosis and decreases the tumorigenic potential of human prostate cancer cells

scientific article published on January 2004

SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care

scientific article published on 07 June 2021

Searching for replication origins in mammalian DNA.

scientific article

Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models

scientific article published on 05 October 2009

Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice

scientific article published on 9 April 2012

Sequence-specific DNA binding protein(s) that bind(s) to a putative human DNA replication origin

scientific article published on 01 May 1988

Short term effects of doxycycline on matrix metalloproteinases 2 and 9.

scientific article published on 4 December 2008

Single-Dose Intracardiac Injection of Pro-Regenerative MicroRNAs Improves Cardiac Function After Myocardial Infarction

scientific article published on 11 January 2017

Spatial juxtaposition of HIV-1 provirus with PML and KAKA bodies as revealed by 3D Immuno DNA FISH

article

Subnuclear distribution of the largest subunit of the human origin recognition complex during the cell cycle.

scientific article

Supporting data on in vitro cardioprotective and proliferative paracrine effects by the human amniotic fluid stem cell secretome

scientific article published on 30 July 2019

Sustained Expression of Vascular Endothelial Growth Factor and Angiopoietin-1 Improves Blood–Spinal Cord Barrier Integrity and Functional Recovery after Spinal Cord Injury ⬇️

scientific article published on October 28, 2010

Systemic Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Delivery Shows Antiatherosclerotic Activity in Apolipoprotein E–Null Diabetic Mice

scientific article published on 25 September 2006

TBL1Y: a new gene involved in syndromic hearing loss

article

Targeted uptake-1 carrier to rescue the failing heart

scientific article published in October 2005

Terminal differentiation of cardiac and skeletal myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteins

scientific journal article

The Basic Domain in HIV-1 Tat Protein as a Target for Polysulfonated Heparin-mimicking Extracellular Tat Antagonists ⬇️

scientific article published on June 26, 1998

The HIV-1 Tat protein: a multifaceted target for novel therapeutic opportunities

scientific article

The TRIM family protein KAP1 inhibits HIV-1 integration.

scientific article published on June 2011

The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets

scholarly article by Thomas P. Peacock published in April 2021

The furin cleavage site of SARS-CoV-2 spike protein is a key determinant for transmission due to enhanced replication in airway cells

scientific article

The global role of biotechnology for non communicable disorders

scientific article published on 02 August 2018

The histone chaperone protein Nucleosome Assembly Protein-1 (hNAP-1) binds HIV-1 Tat and promotes viral transcription

scientific article

The innate immune system in chronic cardiomyopathy: a European Society of Cardiology (ESC) scientific statement from the Working Group on Myocardial Function of the ESC.

scientific article published on 15 January 2018

The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response

scientific article

The renaissance of competitive PCR as an accurate tool for precise nucleic acid quantification

scientific article published on 01 January 2010

The transcriptional co-activator PCAF regulates cdk2 activity

scientific journal article

The transcriptional transactivator Tat selectively regulates viral splicing.

scientific article

Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure

scientific article published on 17 November 2018

Toward standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function

scientific article published on 04 May 2020

Transcellular protein transduction using the Tat protein of HIV-1.

scientific article

Transcellular transfer of active HSV-1 thymidine kinase mediated by an 11-amino-acid peptide from HIV-1 Tat.

scientific article

Transcription and polyadenylation in a short human intergenic region.

scientific article published on June 1997

Transcription-dependent gene looping of the HIV-1 provirus is dictated by recognition of pre-mRNA processing signals

scientific article

Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter.

scientific article published on March 1998

Transgene detection by digital droplet PCR

scientific article

Unacylated Ghrelin Enhances Satellite Cell Function and Relieves the Dystrophic Phenotype in Duchenne Muscular Dystrophy mdx Model.

scientific article published on 24 April 2017

Unacylated Ghrelin Reduces Skeletal Muscle Reactive Oxygen Species Generation and Inflammation and Prevents High-Fat Diet-Induced Hyperglycemia and Whole-Body Insulin Resistance in Rodents.

scientific article published on 28 January 2016

Unacylated ghrelin normalizes skeletal muscle oxidative stress and prevents muscle catabolism by enhancing tissue mitophagy in experimental chronic kidney disease

scientific article

VEGF gene therapy: therapeutic angiogenesis in the clinic and beyond

scientific article

VEGF-B Gene Therapy for the Heart: Proceed with Caution

scientific article published on 22 June 2020

VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9.

scientific article published on 11 July 2018

Vascular endothelial growth factor stimulates skeletal muscle regeneration in vivo

scientific article published in November 2004

Vascular endothelial growth factor-B gene transfer exacerbates retinal and choroidal neovascularization and vasopermeability without promoting inflammation.

scientific article

Virus-mediated gene delivery for human gene therapy

scientific article published on 10 April 2012

Virus-mediated gene transfer to induce therapeutic angiogenesis: where do we stand?

scientific article

miR-200 family members reduce senescence and restore idiopathic pulmonary fibrosis type II alveolar epithelial cell transdifferentiation

scientific article published on 01 October 2019

miR-378a influences vascularization in skeletal muscles

scientific article published on 28 August 2019

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