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List of works by Serena Zacchigna

A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis

scientific article published on 11 August 2021

A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration

scientific article published on 10 August 2021

A novel myogenic cell line with phenotypic properties of muscle progenitors

scientific article published on 24 October 2007

AAV-mediated gene transfer of tissue inhibitor of metalloproteinases-1 inhibits vascular tumor growth and angiogenesis in vivo

scientific article published on January 2004

AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia

scientific article published on 11 June 2015

Adeno-associated virus vectors as therapeutic and investigational tools in the cardiovascular system

scientific article (publication date: 23 May 2014)

Adeno-associated virus-mediated transduction of VEGF165 improves cardiac tissue viability and functional recovery after permanent coronary occlusion in conscious dogs.

scientific article

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

scientific article published in 2022

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

scientific article

Authors' reply

scientific article published on 01 April 2014

Blue laser light inhibits biofilm formation in vitro and in vivo by inducing oxidative stress

scientific article published on 09 October 2019

Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis in mice.

scientific article published on June 2008

Bone marrow mononuclear cells are recruited to the sites of VEGF-induced neovascularization but are not incorporated into the newly formed vessels.

scientific article published on 3 January 2006

Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction.

scientific article published on 17 December 2009

Chapter 20: Gene therapy perspectives for nerve repair

scientific article published on January 2009

Class IV laser therapy as treatment for chemotherapy-induced oral mucositis in onco-haematological paediatric patients: a prospective study

scientific article

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

scientific article

Effect of class IV laser therapy on chemotherapy-induced oral mucositis: a clinical and experimental study.

scientific article

Effect of vascular endothelial growth factor gene therapy on post-traumatic peripheral nerve regeneration and denervation-related muscle atrophy

scientific article published on May 30, 2013

Endothelial cell-cardiomyocyte crosstalk in heart development and disease

scientific article published on 28 February 2019

Enhanced athletic performance on multisite AAV-IGF1 gene transfer coincides with massive modification of the muscle proteome

scientific article published on 26 January 2012

Epigenetic modification at Notch responsive promoters blunts efficacy of inducing notch pathway reactivation after myocardial infarction.

scientific article published on 11 August 2014

Evaluation of nutritional status in head and neck radio-treated patients affected by oral mucositis: efficacy of class IV laser therapy.

scientific article

Evidence for a proangiogenic activity of TNF-related apoptosis-inducing ligand

scientific article

Expression profiling of angiogenic genes for the characterisation of colorectal carcinoma.

scientific article published on 23 July 2008

Extra- and intracellular factors regulating cardiomyocyte proliferation in postnatal life.

scientific article published on 12 March 2014

Functional screening identifies miRNAs inducing cardiac regeneration.

scientific article

Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease

article

Genome-wide RNAi screening identifies host restriction factors critical for in vivo AAV transduction

scientific article

Harnessing the microRNA pathway for cardiac regeneration.

scientific article published on 29 September 2015

Impaired Autonomic Regulation of Resistance Arteries in Mice With Low Vascular Endothelial Growth Factor or Upon Vascular Endothelial Growth Factor Trap Delivery

scientific article published on 06 July 2010

Improved survival of ischemic cutaneous and musculocutaneous flaps after vascular endothelial growth factor gene transfer using adeno-associated virus vectors

scientific article

Improved survival of rat ischemic cutaneous and musculocutaneous flaps after VEGF gene transfer.

scientific article published in January 2007

Improving human interferon-beta production in mammalian cell lines by insertion of an intronic sequence within its naturally uninterrupted gene.

scientific article

In Vivo Functional Selection Identifies Cardiotrophin-1 as a Cardiac Engraftment Factor for Mesenchymal Stromal Cells

scientific article

In vivo activation of a conserved microRNA program induces mammalian heart regeneration

scientific article published on 6 November 2014

In vivo therapeutic potential of mesenchymal stromal cells depends on the source and the isolation procedure.

scientific article

Inducible adeno-associated virus vectors promote functional angiogenesis in adult organisms via regulated vascular endothelial growth factor expression.

scientific article published on 14 May 2009

Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors.

scientific article published in April 2003

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties

scientific article

Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy

scientific article published on 29 April 2010

Intraoperative Margin Control in Transoral Approach for Oral and Oropharyngeal Cancer

scientific article published on 04 October 2018

Is early detection of late-onset Pompe disease a pneumologist's affair? A lesson from an Italian screening study

article

Laser Therapy Inhibits Tumor Growth in Mice by Promoting Immune Surveillance and Vessel Normalization.

scientific article

Loss of the cholesterol-binding protein prominin-1/CD133 causes disk dysmorphogenesis and photoreceptor degeneration

scientific journal article

Lovastatin dose-dependently potentiates the pro-inflammatory activity of lipopolysaccharide both in vitro and in vivo

scientific article published on December 2013

Macrophage microRNA-155 promotes cardiac hypertrophy and failure.

scientific article published on 16 August 2013

Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1

scientific article published on 01 November 2010

MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs

scientific article published on 08 May 2019

Modification of kidney barrier function by the urokinase receptor

scientific article published on 16 December 2007

Modulation of Redox Signaling in Chronic Diseases and Regenerative Medicine

scientific article published on 23 April 2019

Mouse mesenchymal stem cells inhibit high endothelial cell activation and lymphocyte homing to lymph nodes by releasing TIMP-1.

scientific article

Neurovascular signalling defects in neurodegeneration

scientific article published on March 2008

Open questions and novel concepts in oral cancer surgery.

scientific article published on 24 May 2015

Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction.

scientific article published on 26 June 2018

Pentraxin 3 inhibits fibroblast growth factor 2-dependent activation of smooth muscle cells in vitro and neointima formation in vivo

scientific article published on 14 July 2005

Photobiomodulation at Multiple Wavelengths Differentially Modulates Oxidative Stress and

scientific article published on 11 November 2018

SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence

scientific article published in 2023

Same strategy for pitfalls of radiotherapy in different anatomical districts

scientific article published on 21 January 2016

Self-Assembled Nanomicelles as Curcumin Drug Delivery Vehicles: Impact on Solitary Fibrous Tumor Cell Protein Expression and Viability

scientific article published on 17 September 2018

Short term effects of doxycycline on matrix metalloproteinases 2 and 9.

scientific article published on 4 December 2008

Single-Dose Intracardiac Injection of Pro-Regenerative MicroRNAs Improves Cardiac Function After Myocardial Infarction

scientific article published on 11 January 2017

Systemic Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Delivery Shows Antiatherosclerotic Activity in Apolipoprotein E–Null Diabetic Mice

scientific article published on 25 September 2006

Systemic and neuronal inflammatory markers in a mouse model of mevalonate kinase deficiency: a strain-comparative study

scientific article

TIM4 expression by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responses

scientific article published on 14 April 2021

TRAIL shows potential cardioprotective activity

Taming the Notch Transcriptional Regulator for Cancer Therapy.

scientific article published on 15 February 2018

Terminal differentiation of cardiac and skeletal myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteins

scientific journal article

The diagnostic performance parameters of Narrow Band Imaging: A preclinical and clinical study.

scientific article published on 2 August 2016

The global role of biotechnology for non communicable disorders

scientific article published on 02 August 2018

The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response

scientific article

Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure

scientific article published on 17 November 2018

Transgene detection by digital droplet PCR

scientific article

VEGF gene therapy: therapeutic angiogenesis in the clinic and beyond

scientific article

VEGF121 and VEGF165 differentially promote vessel maturation and tumor growth in mice and humans

scientific article published on April 2016

VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9.

scientific article published on 11 July 2018

Vascular endothelial growth factor-B gene transfer exacerbates retinal and choroidal neovascularization and vasopermeability without promoting inflammation.

scientific article

Virus-mediated gene delivery for human gene therapy

scientific article published on 10 April 2012

Wet-dry-wet drug screen leads to the synthesis of TS1, a novel compound reversing lung fibrosis through inhibition of myofibroblast differentiation

scientific article published on 17 December 2021

Will the mininvasive approach challenge the old paradigms in oral cancer surgery?

scientific article