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List of works by Alexander Eggel

A novel bispecific DARPin targeting FcγRIIB and FcεRI-bound IgE inhibits allergic responses.

scientific article

A revival of parabiosis in biomedical research

scientific article

A time-resolved fluorescence resonance energy transfer assay suitable for high-throughput screening for inhibitors of immunoglobulin E-receptor interactions.

scientific article

Accelerated disassembly of IgE–receptor complexes by a disruptive macromolecular inhibitor

scientific article

Accuracy of serological testing for SARS-CoV-2 antibodies: first results of a large mixed-method evaluation study

scientific article published on 30 September 2020

An Engineered Disulfide Bond Reversibly Traps the IgE-Fc3-4 in a Closed, Nonreceptor Binding Conformation

scientific article

DARPins against a functional IgE epitope ⬇️

scientific article published on July 29, 2010

DARPins as bispecific receptor antagonists analyzed for immunoglobulin E receptor blockage.

scientific article

Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age

scientific article published on 06 July 2020

Exposure to avian coronavirus vaccines is associated with increased levels of SARS‐CoV ‐2‐cross‐reactive antibodies

IL-3 but not monomeric IgE regulates FcεRI levels and cell survival in primary human basophils.

scientific article

IgE-associated allergic disorders: recent advances in etiology, diagnosis, and treatment

scientific article

Improved FcγRIIb targeting functionally translates into enhanced inhibition of basophil activation

scientific article published on 14 February 2014

Inhibition of ongoing allergic reactions using a novel anti-IgE DARPin-Fc fusion protein.

scientific article

NADPH oxidase-independent formation of extracellular DNA traps by basophils

scientific article

Past, present and future of anti-IgE biologicals

scientific article published on 06 April 2020

Serological testing for SARS-CoV-2 antibodies in clinical practice: A comparative diagnostic accuracy study

Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange.

scientific article published on 19 May 2016

The ageing systemic milieu negatively regulates neurogenesis and cognitive function.

scientific article

The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab

scientific article published on 08 January 2020

β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis

scientific article

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