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List of works by Alexander Ishchenko

7,8-Dihydro-8-oxoadenine, a highly mutagenic adduct, is repaired by Escherichia coli and human mismatch-specific uracil/thymine-DNA glycosylases

scientific article published on 2 December 2012

A molecular beacon assay for measuring base excision repair activities.

scientific article published on June 2004

Aberrant repair initiated by mismatch-specific thymine-DNA glycosylases provides a mechanism for the mutational bias observed in CpG islands.

scientific article

African swine fever virus AP endonuclease is a redox-sensitive enzyme that repairs alkylating and oxidative damage to DNA.

scientific article

Age-associated changes in oxidative damage and the activity of antioxidant enzymes in rats with inherited overgeneration of free radicals.

scientific article published on January 2006

An interplay of the base excision repair and mismatch repair pathways in active DNA demethylation

scientific article

Apurinic/apyrimidinic endonuclease Apn1 from Saccharomyces cerevisiae is recruited to the nucleotide incision repair pathway: Kinetic and structural features

scientific article published on 26 June 2018

Biochemical and structural characterization of the glycosylase domain of MBD4 bound to thymine and 5-hydroxymethyuracil-containing DNA

scientific article

Characterization of Caenorhabditis elegans exonuclease-3 and evidence that a Mg2+-dependent variant exhibits a distinct mode of action on damaged DNA.

scientific article

Characterization of DNA ADP-ribosyltransferase activities of PARP2 and PARP3: new insights into DNA ADP-ribosylation.

scientific article

Characterization of DNA substrate specificities of apurinic/apyrimidinic endonucleases from Mycobacterium tuberculosis

scientific article published on 22 May 2015

Characterization of biochemical properties of an apurinic/apyrimidinic endonuclease from Helicobacter pylori

scientific article published in PLoS ONE

Conformational Dynamics of DNA Repair by Escherichia coli Endonuclease III

scientific article published on 13 April 2015

Coupling of the nucleotide incision and 3'-->5' exonuclease activities in Escherichia coli endonuclease IV: Structural and genetic evidences.

scientific article published on 12 September 2009

Dna is a New Target of Parp3.

scientific article published on 8 March 2018

Endogenous DNA damage clusters in human hematopoietic stem and progenitor cells.

scientific article

Enzymology of repair of etheno-adducts.

scientific article published on October 2003

Excision of 8-oxoguanine from methylated CpG dinucleotides by human 8-oxoguanine DNA glycosylase.

scientific article published on 13 August 2013

Functional characterization of the Caenorhabditis elegans DNA repair enzyme APN-1.

scientific article published on 20 July 2012

Functional variants of human APE1 rescue the DNA repair defects of the yeast AP endonuclease/3'-diesterase-deficient strain

scientific article published on 09 August 2014

Genetic and biochemical characterization of human AP endonuclease 1 mutants deficient in nucleotide incision repair activity

scientific article

High resolution characterization of formamidopyrimidine-DNA glycosylase interaction with its substrate by chemical cross-linking and mass spectrometry using substrate analogs.

scientific article published on 22 August 2006

Highly mutagenic exocyclic DNA adducts are substrates for the human nucleotide incision repair pathway

scientific article

Initiation of 8-oxoguanine base excision repair within trinucleotide tandem repeats.

scientific article

Insight into mechanisms of 3'-5' exonuclease activity and removal of bulky 8,5'-cyclopurine adducts by apurinic/apyrimidinic endonucleases

scientific article

Kinetic mechanism of human apurinic/apyrimidinic endonuclease action in nucleotide incision repair

scientific article published on 01 February 2011

Lys98 Substitution in Human AP Endonuclease 1 Affects the Kinetic Mechanism of Enzyme Action in Base Excision and Nucleotide Incision Repair Pathways ⬇️

scientific article published on January 1, 2011

Major oxidative products of cytosine are substrates for the nucleotide incision repair pathway.

scientific article

New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways.

scientific article

Poly(ADP-ribose) polymerases covalently modify strand break termini in DNA fragments in vitro.

scientific article published on 28 July 2016

Pre-steady-state fluorescence analysis of damaged DNA transfer from human DNA glycosylases to AP endonuclease APE1.

scientific article published on 31 July 2014

Pre-steady-state kinetic analysis of damage recognition by human single-strand selective monofunctional uracil-DNA glycosylase SMUG1.

scientific article

Presence of base excision repair enzymes in the wheat aleurone and their activation in cells undergoing programmed cell death

scientific article published on 5 August 2011

Recognition of damaged DNA by Escherichia coli Fpg protein: insights from structural and kinetic data

scientific article

Single-stranded oligodeoxyribonucleotides are substrates of Fpg protein from Escherichia coli

scientific article published on 01 December 1999

Step-by-step mechanism of DNA damage recognition by human 8-oxoguanine DNA glycosylase.

scientific article

Structural comparison of AP endonucleases from the exonuclease III family reveals new amino acid residues in human AP endonuclease 1 that are involved in incision of damaged DNA

scientific article

Substrate specificity of homogeneous monkeypox virus uracil-DNA glycosylase.

scientific article published on 2 October 2007

TET2-mediated 5-hydroxymethylcytosine induces genetic instability and mutagenesis.

scientific article published on 24 May 2016

The 3'->5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae.

scientific article

The hMsh2-hMsh6 complex acts in concert with monoubiquitinated PCNA and Pol η in response to oxidative DNA damage in human cells

scientific article

The major Arabidopsis thaliana apurinic/apyrimidinic endonuclease, ARP is involved in the plant nucleotide incision repair pathway

scientific article published on 29 October 2016

The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway.

scientific article published on 2 January 2004

The mechanism of human tyrosyl-DNA phosphodiesterase 1 in the cleavage of AP site and its synthetic analogs.

scientific article published on 31 October 2013

The role of His-83 of yeast apurinic/apyrimidinic endonuclease Apn1 in catalytic incision of abasic sites in DNA.

scientific article published on 10 March 2015

The role of the N-terminal domain of human apurinic/apyrimidinic endonuclease 1, APE1, in DNA glycosylase stimulation

scientific article published on 11 February 2018

Thermodynamic, kinetic and structural basis for recognition and repair of abasic sites in DNA by apurinic/apyrimidinic endonuclease from human placenta.

scientific article

Thermodynamic, kinetic, and structural basis for recognition and repair of 8-oxoguanine in DNA by Fpg protein from Escherichia coli.

scientific article

Uncoupling of the base excision and nucleotide incision repair pathways reveals their respective biological roles.

scholarly article

Uracil in duplex DNA is a substrate for the nucleotide incision repair pathway in human cells

scientific article

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