List of works - Zhinan Xu

A CRISPR-Cas12a-Derived Biosensor Enabling Portable Personal Glucose Meter Readout for Quantitative Detection of SARS-CoV-2

scientific article published on 06 January 2021

A Single Cas9-VPR Nuclease for Simultaneous Gene Activation, Repression, and Editing in Saccharomyces cerevisiae

scientific article published on 28 August 2020

A high-throughput method for screening of rapamycin-producing strains of Streptomyces hygroscopicus by cultivation in 96-well microtiter plates.

scientific article published in August 2005

Application of inkjet printing technique for biological material delivery and antimicrobial assays.

scientific article published on 14 January 2011

Bio-Inspired Aquaporinz Containing Double-Skinned Forward Osmosis Membrane Synthesized through Layer-by-Layer Assembly.

scientific article published on 10 August 2015

CRISPR-Cas12a-Assisted Multicolor Biosensor for Semiquantitative Point-of-Use Testing of the Nopaline Synthase Terminator in Genetically Modified Crops by Unaided Eyes

scientific article published on 13 October 2020

Cell-Free Expression of Unnatural Amino Acid Incorporated Aquaporin SS9 with Improved Separation Performance in Biomimetic Membranes

scientific article published on 27 September 2018

Characterization of NocL involved in thiopeptide nocathiacin I biosynthesis: a [4Fe-4S] cluster and the catalysis of a radical S-adenosylmethionine enzyme.

scientific article

Cloning and expression of human beta-defensin-2 gene in Escherichia coli

scientific article published on 01 February 2002

Cloning and expression of the HIV protein in Escherichia coli cell-free system.

scientific article published on 26 September 2007

Coagulative biomarkers on admission to the ICU predict acute kidney injury and mortality in patients with septic shock caused by intra-abdominal infection

scientific article published on 04 September 2019

Combined genome editing and transcriptional repression for metabolic pathway engineering in Corynebacterium glutamicum using a catalytically active Cas12a

scientific article published on 03 October 2019

Effects of cultivation conditions on the production of natamycin with Streptomyces gilvosporeus LK-196 ⬇️

scientific article published on September 4, 2007

Effects of medium composition on the production of plasmid DNA vector potentially for human gene therapy.

scientific article published on May 2005

Efficient Production of Hydroxylated Human-Like Collagen Via the Co-Expression of Three Key Genes in Escherichia coli Origami (DE3).

scientific article published on 29 December 2015

Efficient biotransformation of vitamin D3 to 25-hydroxyvitamin D3 by a newly isolated Bacillus cereus strain

scientific article published on 27 November 2019

Efficient chemoenzymatic synthesis of uridine 5'-diphosphate N-acetylglucosamine and uridine 5'-diphosphate N-trifluoacetyl glucosamine with three recombinant enzymes

scientific article published on 24 May 2016

Efficient expression and primary purification of 6-his tagged human Fas ligand in Dictyostelium discoideum.

scientific article published on 10 March 2007

Efficient expression of aquaporin Z in Escherichia coli cell-free system using different fusion vectors.

scientific article published in February 2010

Efficient expression, purification, and characterization of a novel FAD-dependent glucose dehydrogenase from Aspergillus terreus in Pichia pastoris

scientific article published on 01 November 2014

Efficient poly(β-L-malic acid) production from cassava hydrolysate by cell recycle of Aureobasidium pullulans

scientific article published in 2022

Efficient production of S-adenosyl-l-methionine from dl-methionine in metabolic engineered Saccharomyces cerevisiae

scientific article published on 18 September 2019

Elimination of the mycotoxin citrinin production in the industrial important strain Monascus purpureus SM001.

scientific article published on 21 August 2009

Engineered production of iso-migrastatin in heterologous Streptomyces hosts

scientific article

Engineering of global regulator cAMP receptor protein (CRP) in Escherichia coli for improved lycopene production.

scientific article published on 14 February 2015

Enhanced butyric acid tolerance and bioproduction by Clostridium tyrobutyricum immobilized in a fibrous bed bioreactor

scientific article published on 01 January 2011

Enhanced fed-batch production of pyrroloquinoline quinine in Methylobacillus sp. CCTCC M2016079 with a two-stage pH control strategy.

scientific article published on 3 April 2017

Enhanced functional expression of aquaporin Z via fusion of in situ cleavable leader peptides in Escherichia coli cell-free system

scientific article

Enhanced production of 5-hydroxytryptophan through the regulation of L-tryptophan biosynthetic pathway

scientific article published on 31 January 2020

Expression, characterization and mutagenesis of an FAD-dependent glucose dehydrogenase from Aspergillus terreus.

scientific article

FK506 maturation involves a cytochrome p450 protein-catalyzed four-electron C-9 oxidation in parallel with a C-31 O-methylation.

scientific article published on 22 February 2013

Functional Expression of Eukaryotic Cytochrome P450s in Yeast

scientific article published on 18 November 2020

Generation of high rapamycin producing strain via rational metabolic pathway-based mutagenesis and further titer improvement with fed-batch bioprocess optimization.

scientific article published in October 2010

High-level expression of a soluble functional antimicrobial peptide, human beta-defensin 2, in Escherichia coli.

scientific article published in March 2006

High-level expression of human beta-defensin-2 gene with rare codons in E. coli cell-free system.

scientific article published in January 2006

High-level expression of soluble subunit b of F1F0 ATP synthase in Escherichia coli cell-free system.

scientific article

High-level production of poly (β-l-malic acid) with a new isolated Aureobasidium pullulans strain ⬇️

scientific article published on June 8, 2011

High-level soluble expression of one model olfactory receptor (ODR-10) in Escherichia coli cell-free system

scientific article published on 4 October 2013

Identification and characterization of a new erythromycin biosynthetic gene cluster in Actinopolyspora erythraea YIM90600, a novel erythronolide-producing halophilic actinomycete isolated from salt field

scientific article

Improving the productivity of S-adenosyl-l-methionine by metabolic engineering in an industrial Saccharomyces cerevisiae strain

scientific article published on 7 August 2016

Iso-migrastatin Titer Improvement in the Engineered Streptomyces lividans SB11002 Strain by Optimization of Fermentation Conditions. ⬇️

scientific article published on August 2010

Long-term production of soluble human Fas ligand through immobilization of Dictyostelium discoideum in a fibrous bed bioreactor.

scientific article published on 18 November 2008

Medium optimization for pyrroloquinoline quinone (PQQ) production by Methylobacillus sp. zju323 using response surface methodology and artificial neural network-genetic algorithm

scientific article published on 27 April 2017

Metabolic engineering of Lactococcus lactis for high level accumulation of glutathione and S-adenosyl-L-methionine

scientific article published on 14 November 2019

Metabolic pathway engineering for high-level production of 5-hydroxytryptophan in Escherichia coli

scientific article published on 19 June 2018

Organic chemicals from bioprocesses in China.

scientific article published on January 2010

Phosphoenolpyruvate-dependent phosphorylation of sucrose by Clostridium tyrobutyricum ZJU 8235: evidence for the phosphotransferase transport system

scientific article published in September 2009

Production of bioactive human beta-defensin-3 in Escherichia coli by soluble fusion expression.

scientific article

Recent advances in inkjet dispensing technologies: applications in drug discovery ⬇️

scientific article published on June 24, 2012

Reconstitution of the peptidoglycan cytoplasmic precursor biosynthetic pathway in cell-free system and rapid screening of antisense oligonucleotides for Mur enzymes

scientific article published on 07 January 2014

Tandem repeat mhBD2 gene enhance the soluble fusion expression of hBD2 in Escherichia coli.

scientific article published on 2 December 2005

The Improvement of SAM Accumulation by Integrating the Endogenous Methionine Adenosyltransferase Gene SAM2 in Genome of the Industrial Saccharomyces cerevisiae Strain

scientific article published on 4 January 2016

The main byproducts and metabolic flux profiling of γ-PGA-producing strain B. subtilis ZJU-7 under different pH values.

scientific article

Titer improvement of iso-migrastatin in selected heterologous Streptomyces hosts and related analysis of mRNA expression by quantitative RT–PCR ⬇️

scientific article published on December 4, 2010

List of works by Zhinan Xu

A CRISPR-Cas12a-Derived Biosensor Enabling Portable Personal Glucose Meter Readout for Quantitative Detection of SARS-CoV-2

A Single Cas9-VPR Nuclease for Simultaneous Gene Activation, Repression, and Editing in Saccharomyces cerevisiae

A high-throughput method for screening of rapamycin-producing strains of Streptomyces hygroscopicus by cultivation in 96-well microtiter plates.

Application of inkjet printing technique for biological material delivery and antimicrobial assays.

Bio-Inspired Aquaporinz Containing Double-Skinned Forward Osmosis Membrane Synthesized through Layer-by-Layer Assembly.

CRISPR-Cas12a-Assisted Multicolor Biosensor for Semiquantitative Point-of-Use Testing of the Nopaline Synthase Terminator in Genetically Modified Crops by Unaided Eyes

Cell-Free Expression of Unnatural Amino Acid Incorporated Aquaporin SS9 with Improved Separation Performance in Biomimetic Membranes

Characterization of NocL involved in thiopeptide nocathiacin I biosynthesis: a [4Fe-4S] cluster and the catalysis of a radical S-adenosylmethionine enzyme.

Cloning and expression of human beta-defensin-2 gene in Escherichia coli

Cloning and expression of the HIV protein in Escherichia coli cell-free system.

Coagulative biomarkers on admission to the ICU predict acute kidney injury and mortality in patients with septic shock caused by intra-abdominal infection

Combined genome editing and transcriptional repression for metabolic pathway engineering in Corynebacterium glutamicum using a catalytically active Cas12a

Effects of cultivation conditions on the production of natamycin with Streptomyces gilvosporeus LK-196 ⬇️

Effects of medium composition on the production of plasmid DNA vector potentially for human gene therapy.

Efficient Production of Hydroxylated Human-Like Collagen Via the Co-Expression of Three Key Genes in Escherichia coli Origami (DE3).

Efficient biotransformation of vitamin D3 to 25-hydroxyvitamin D3 by a newly isolated Bacillus cereus strain

Efficient chemoenzymatic synthesis of uridine 5'-diphosphate N-acetylglucosamine and uridine 5'-diphosphate N-trifluoacetyl glucosamine with three recombinant enzymes

Efficient expression and primary purification of 6-his tagged human Fas ligand in Dictyostelium discoideum.

Efficient expression of aquaporin Z in Escherichia coli cell-free system using different fusion vectors.

Efficient expression, purification, and characterization of a novel FAD-dependent glucose dehydrogenase from Aspergillus terreus in Pichia pastoris

Efficient poly(β-L-malic acid) production from cassava hydrolysate by cell recycle of Aureobasidium pullulans

Efficient production of S-adenosyl-l-methionine from dl-methionine in metabolic engineered Saccharomyces cerevisiae

Elimination of the mycotoxin citrinin production in the industrial important strain Monascus purpureus SM001.

Engineered production of iso-migrastatin in heterologous Streptomyces hosts

Engineering of global regulator cAMP receptor protein (CRP) in Escherichia coli for improved lycopene production.

Enhanced butyric acid tolerance and bioproduction by Clostridium tyrobutyricum immobilized in a fibrous bed bioreactor

Enhanced fed-batch production of pyrroloquinoline quinine in Methylobacillus sp. CCTCC M2016079 with a two-stage pH control strategy.

Enhanced functional expression of aquaporin Z via fusion of in situ cleavable leader peptides in Escherichia coli cell-free system

Enhanced production of 5-hydroxytryptophan through the regulation of L-tryptophan biosynthetic pathway

Expression, characterization and mutagenesis of an FAD-dependent glucose dehydrogenase from Aspergillus terreus.

FK506 maturation involves a cytochrome p450 protein-catalyzed four-electron C-9 oxidation in parallel with a C-31 O-methylation.

Functional Expression of Eukaryotic Cytochrome P450s in Yeast

Generation of high rapamycin producing strain via rational metabolic pathway-based mutagenesis and further titer improvement with fed-batch bioprocess optimization.

High-level expression of a soluble functional antimicrobial peptide, human beta-defensin 2, in Escherichia coli.

High-level expression of human beta-defensin-2 gene with rare codons in E. coli cell-free system.

High-level expression of soluble subunit b of F1F0 ATP synthase in Escherichia coli cell-free system.

High-level production of poly (β-l-malic acid) with a new isolated Aureobasidium pullulans strain ⬇️

High-level soluble expression of one model olfactory receptor (ODR-10) in Escherichia coli cell-free system

Identification and characterization of a new erythromycin biosynthetic gene cluster in Actinopolyspora erythraea YIM90600, a novel erythronolide-producing halophilic actinomycete isolated from salt field

Improving the productivity of S-adenosyl-l-methionine by metabolic engineering in an industrial Saccharomyces cerevisiae strain

Iso-migrastatin Titer Improvement in the Engineered Streptomyces lividans SB11002 Strain by Optimization of Fermentation Conditions. ⬇️

Long-term production of soluble human Fas ligand through immobilization of Dictyostelium discoideum in a fibrous bed bioreactor.

Medium optimization for pyrroloquinoline quinone (PQQ) production by Methylobacillus sp. zju323 using response surface methodology and artificial neural network-genetic algorithm

Metabolic engineering of Lactococcus lactis for high level accumulation of glutathione and S-adenosyl-L-methionine

Metabolic pathway engineering for high-level production of 5-hydroxytryptophan in Escherichia coli

Organic chemicals from bioprocesses in China.

Phosphoenolpyruvate-dependent phosphorylation of sucrose by Clostridium tyrobutyricum ZJU 8235: evidence for the phosphotransferase transport system

Production of bioactive human beta-defensin-3 in Escherichia coli by soluble fusion expression.

Recent advances in inkjet dispensing technologies: applications in drug discovery ⬇️

Reconstitution of the peptidoglycan cytoplasmic precursor biosynthetic pathway in cell-free system and rapid screening of antisense oligonucleotides for Mur enzymes

Tandem repeat mhBD2 gene enhance the soluble fusion expression of hBD2 in Escherichia coli.

The Improvement of SAM Accumulation by Integrating the Endogenous Methionine Adenosyltransferase Gene SAM2 in Genome of the Industrial Saccharomyces cerevisiae Strain

The main byproducts and metabolic flux profiling of γ-PGA-producing strain B. subtilis ZJU-7 under different pH values.

Titer improvement of iso-migrastatin in selected heterologous Streptomyces hosts and related analysis of mRNA expression by quantitative RT–PCR ⬇️