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List of works by Samuel K Lai

A minimal physiologically based pharmacokinetic model that predicts anti-PEG IgG-mediated clearance of PEGylated drugs in human and mouse

scientific article published on 05 June 2018

Antibody-Mediated Immobilization of Virions in Mucus

scientific article published on 29 August 2019

Antibody-mediated trapping in biological hydrogels is governed by sugar-sugar hydrogen bonds

scientific article published on 05 March 2020

Biodegradable Nanoparticles Composed Entirely of Safe Materials that Rapidly Penetrate Human Mucus ⬇️

scientific article published on February 18, 2011

Common Gene Therapy Viral Vectors Do Not Efficiently Penetrate Sputum from Cystic Fibrosis Patients ⬇️

scientific article published on May 27, 2011

Diffusion of Immunoglobulin G in Shed Vaginal Epithelial Cells and in Cell-Free Regions of Human Cervicovaginal Mucus

scientific article

Efficient and Highly Specific Gene Transfer Using Mutated Lentiviral Vectors Redirected with Bispecific Antibodies

scientific article published on 21 January 2020

Engineering Polymer-Binding Bispecific Antibodies for Enhanced Pretargeted Delivery of Nanoparticles to Mucus-Covered Epithelium

scientific article published on 21 March 2019

Enhanced Trapping of HIV-1 by Human Cervicovaginal Mucus Is Associated with Lactobacillus crispatus-Dominant Microbiota

scientific article

Enhancement of airway gene transfer by DNA nanoparticles using a pH-responsive block copolymer of polyethylene glycol and poly-l-lysine ⬇️

scientific article published on December 17, 2011

Experimental Data and PBPK Modeling Quantify Antibody Interference in PEGylated Drug Carrier Delivery

scientific article published in 2021

Minimizing biases associated with tracking analysis of submicron particles in heterogeneous biological fluids

scientific article

Modeling Barrier Properties of Intestinal Mucus Reinforced with IgG and Secretory IgA against Motile Bacteria

scientific article published on 03 July 2019

Mucoadhesive Nanoparticles May Disrupt the Protective Human Mucus Barrier by Altering Its Microstructure ⬇️

scientific article published on June 29, 2011

Non-degradative intracellular trafficking of highly compacted polymeric DNA nanoparticles ⬇️

scientific article published on October 30, 2011

Pretargeting with bispecific fusion proteins facilitates delivery of nanoparticles to tumor cells with distinct surface antigens

scientific article published on 28 March 2017

Rapid Transport of Muco-Inert Nanoparticles in Cystic Fibrosis Sputum Treated with N -Acetyl Cysteine ⬇️

scientific article published on February 1, 2011

Real-time multiple particle tracking of gene nanocarriers in complex biological environments.

scientific article

Robust antigen-specific tuning of the nanoscale barrier properties of biogels using matrix-associating IgG and IgM antibodies

scientific article published on 14 March 2019

The Cervicovaginal Microbiota-Host Interaction Modulates Chlamydia trachomatis Infection

scientific article published on 13 August 2019

The cervicovaginal mucus barrier to HIV-1 is diminished in bacterial vaginosis

scientific article published on 23 January 2020

Transport of metal oxide nanoparticles and single-walled carbon nanotubes in human mucus ⬇️

scientific article published on July 29, 2011

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